The invention provides a method for combating biofilm, said method comprising contacting a biofilm with a composition comprising an effective amount of antimicrobial peptide biofilm enzyme combinations, preferably in the form of a fusion protein. The biofilm may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides a composition for use in the treatment or prevention of a biofilm in a subject, particularly in the oral cavity.

The invention provides a method for combating biofilm, said method comprising contacting a biofilm with a composition comprising an effective amount of antimicrobial peptide biofilm enzyme combinations, preferably in the form of a fusion protein. The biofilm may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides a composition for use in the treatment or prevention of a biofilm in a subject, particularly in the oral cavity.

Provided is a method of reducing senescence in a cell or subject, or treating or preventing a symptom or disease associated therewith, by administering a BRAF inhibitor to the cell or subject.

Provided are biocompatible topical compositions including a novel combination of an inflammatory management agent, a vascular repair agent, a neurogenic agent, a sebum suppression agent and an exfoliating agent. Also provided are methods for treating, preventing or ameliorating rosacea, a symptom thereof or a condition related thereto by administering the biocompatible topical compositions describe herein.

Provided are biocompatible topical compositions including a novel combination of an inflammatory management agent, a vascular repair agent, a neurogenic agent, a sebum suppression agent and an exfoliating agent. Also provided are methods for treating, preventing or ameliorating rosacea, a symptom thereof or a condition related thereto by administering the biocompatible topical compositions describe herein.

The present invention relates to a method for preparing a protein cage which comprises: a 1.sup.st step of preparing an amphiphilic polymer comprising a 1.sup.st hydrophobic polymer and a 1.sup.st hydrophilic functional group; a 2.sup.nd step of preparing a hydrophilic protein comprising a 2.sup.nd functional group binding to the 1.sup.st functional group; a 3.sup.rd step of forming an amphiphilic polymer-protein hybrid by the binding of the 1.sup.st functional group and the 2.sup.nd functional group, and forming core-shell structured particles comprising a protein shell and an amphiphilic polymer core by the self-assembly of the amphiphilic polymer in a hydrophilic solvent; and a fourth step of removing some or all of the hydrophobic polymer of the core part from the core-shell structured particles.

The present invention relates to a method for preparing a protein cage which comprises: a 1.sup.st step of preparing an amphiphilic polymer comprising a 1.sup.st hydrophobic polymer and a 1.sup.st hydrophilic functional group; a 2.sup.nd step of preparing a hydrophilic protein comprising a 2.sup.nd functional group binding to the 1.sup.st functional group; a 3.sup.rd step of forming an amphiphilic polymer-protein hybrid by the binding of the 1.sup.st functional group and the 2.sup.nd functional group, and forming core-shell structured particles comprising a protein shell and an amphiphilic polymer core by the self-assembly of the amphiphilic polymer in a hydrophilic solvent; and a fourth step of removing some or all of the hydrophobic polymer of the core part from the core-shell structured particles.

Provided is a dry cosmetic sheet including: a dry support formed of a mesh, the mesh being made of a woven silver yarn; and a dry membrane laminated on the support, the dry membrane being capable of being attached to a users skin, and the dry membrane being formed of a fiber web, the fiber web being formed of accumulated electrospun fibers, each of the electrospun fibers being formed of a single homogeneous mixture containing a water-soluble polymer, a water-insoluble polymer, and a functional material for skin care in a dry state, the functional material being capable of releasing from the fiber by dissolution of the water-soluble polymer when the dry cosmetic sheet is moisturized. Each of the electrospun fibers has a homogenous distribution of the water-soluble polymer, the water-insoluble polymer, and the functional material.

A composition for enhancing protein strength according to the present invention contains an aminosilane compound capable of covalent binding with a protein of hair, scalp, skin, nails, leather, or textile, so that the protein and the amino silane compound form a covalent bond, and thus the composition can improve the protein strength enhancement effect and maximize the semi-permanent protein strength enhancement effect.

A composition for enhancing protein strength according to the present invention contains an aminosilane compound capable of covalent binding with a protein of hair, scalp, skin, nails, leather, or textile, so that the protein and the amino silane compound form a covalent bond, and thus the composition can improve the protein strength enhancement effect and maximize the semi-permanent protein strength enhancement effect.