Disclosed are personal care compositions, e.g., skin care compositions, comprising an acyl glutamate, e.g., sodium cocoyl glutamate, in an amount of from 1% to 10% by weight of the composition and at least one topically active compound, wherein the at least one topically active compound comprises a vitamin, as well as to methods of using these compositions.

In some aspects, the techniques described herein relate to a topical dermatologic acne treatment method using a cream. The treatment method uses two steps, first providing a bactericidal component and second providing a skin revitalizing complex. The bactericidal component clears the acne causing bacteria. The subsequent skin revitalizing complex revitalizes and conditions the skin and aids in return of natural skin flora and microbiome to prevent subsequent outbreaks. The skin revitalizing complex can include a variety of components such as: niacinamide, retinol, bakuchiol, green coffee bean extract, green tea extract, epilobium fleischeri extract, citric acid, dimethicone, and pentaerythrityl tetracaprylate. The skin revitalizing complex restores natural elasticity and oil production of the skin, decrease sebum production, and provide necessary conditioning of the skin to provide for the natural skin flora and microbiome to repopulate and flourish on a surface of the skin.

[Problem to be Solved]

Provided is a delivery carrier into the cell having high antioxidant activity, intracellular absorbability, intracellular disintegration property, stability and safety, which have high delivery property of the active ingredient to cell and living tissues.

[Solution]

The delivery carrier into cells includes a vitamin derivative with co-activation of both autophagy-related genes and protease synthesis genes, a polymer molecule containing stimulatory reactivity, an emulsion stabilizer, an active ingredient, and a lipid, thereby providing a delivery carrier into cells with high delivery properties of the active ingredient to cells and living tissues.

Disclosed is a method of treating a fine line or wrinkle in a person's skin, the method comprising topically applying to the fine line or wrinkle a composition comprising an effective amount of Commiphora mukul resin or an extract thereof that includes oleo gum resin, glycerin, water, and hyaluronic acid or a salt form thereof, wherein topical application of the composition to the fine line or wrinkle reduces the appearance of the fine line or wrinkle.

A hydrogel-fabric composite for cosmetic and therapeutic applications. This application allows the shape retaining solidified gel structure or multi gel composite of a desired hydrogel or blend of hydrogels to disperse the active solutes within the gel more evenly while maintaining activity and then resulting in a set gel shape that conforms with an underlying fabric substrate. Specifically, having the active solutes dispersed within the gel provides an even concentration of active solutes and penetrates the skin over a set amount of time due to the concentration gradient. Further, the temperature constraints of active solute ingredients while still suspending them within the hydrogel for cosmetic use allow for adequate suspension and dissolution of active ingredients throughout the final gel product. Shape retaining Hydrogels, when used with specific active solutes, will remain translucent inferring the purity of the product. Preferred hydrogels to be used in cosmetic facemasks include agar, agarose, carrageenan, carbomers, carboxymethyl cellulose, ethyl cellulose, gelatin, hydroxyethyl cellulose, hydroxypropyl cellulose, magnesium aluminum silicate (veegum), methylcellulose, poloxamers, polyvinyl alcohol, sodium alginate, tragacanth gum, and xanthan hum. Use of a specific hydrogel from this list will depend on which active ingredients are desired to be included in the final product. The process described herein allows for increased dissolution of active ingredients into the final product.

Methods and compositions for improving the appearance of skin are provided. The methods and compositions are especially suited for improving sallow-looking skin by enhancing bilirubin degradation in skin. The methods and compositions herein utilize one or more sucrose esters, which demonstrate a surprising ability to reduce bilirubin levels. The method involves applying a skin care composition containing an effective amount of a sucrose ester to a target portion of skin where a reduction in bilirubin level is desired.

The present disclosure provides esters of a retinoid and an alcohol selected from the group consisting of tocopherols and tert-butylhydroquinone, such as esters of Formula (I). The present disclosure also provides compositions and kits comprising the esters, methods of producing the esters, and methods of using the esters (e.g., for treating or preventing a skin disease, slowing the ageing of the skin, improving the appearance of the skin, or modulating a retinoid receptor).

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The present invention relates to methods of increasing one or more of collagen, elastin, fibronectin, and hyaluronic acid gene expression in the skin of a subject comprising topically administering to the subject a hyaluronic acid compound and a retinoid in one or more compositions. The methods improve the look, feel and/or appearance of the skin, hydrate the skin, plump the skin, improve skin elasticity, improve the appearance of fine lines and wrinkles, reduce the depth, length, or width of fine lines and wrinkles, and smooth the skin. The present invention also relates to cosmetic compositions comprising a hyaluronic acid compound wherein the composition is anhydrous.

The present invention relates to a composition, notably a cosmetic composition, in particular for making up and/or caring for keratin materials, comprising at least retinol, di-t-butyl pentaerythrityl tetrahydroxycinnamate and an ethylenediaminedisuccinic acid salt.

A frozen serum and applicator thereof is disclosed, including a mold having a first half releasably engaged with a second half. When engaged, the first half and the second half form a reservoir therebetween to accept a volume of a serum. The serum is frozen within the mold to produce a frozen serum having at least one receiver molded thereon to releasable engage with an applicator configured to permit the frozen serum to be rolled. An opening is provided on the mold to permit the serum to be disposed within the reservoir.