Pouches, for example pouches that contain one or more oral care active agents, and more particularly pouches employing a water-soluble fibrous wall material, pouches employing a fibrous wall material that ruptures during use, pouches employing an apertured film wall material and methods for making same, are provided.

A composition comprising: (i) an antidandruff agent; (ii) a wax or a wax-like substance in which said antidandruff agent is soluble or dispersible, where melting point of said wax and said substance is 30° C. to 105° C. and where said substance is not a UV absorbing sunscreen; and, (iii) a cationic polymer having weight average molecular weight of 103 Da to 107 Da, where said composition is in the form of particles of particle size 0.1 to 1000 μm and where said wax-like substance is a C13 to 35 fatty alcohol; where said wax is at least one of beeswax, Chinese wax, lanolin, shellac wax, spermaceti, bayberry wax, candelilla wax, carnauba wax, castor wax, esparto wax, Japan wax, ouricury wax, rice bran wax, soy wax, tallow tree wax, ceresin wax, montan wax, ozocerite or peat wax.

The invention provides a fluorinated chitosan derivative as a drug carrier, which has the following structure: a fluorine-containing compound covalently attached to the backbone of chitosan. The chitosan has a molecular weight in the range of 1000-5000000, a degree of deacetylation of not less than 55%, and a viscosity in the range of 25-1000 cps. The fluorine-containing compound is a fluorine-containing aliphatic chain shown by the following chemical formula (I)

##STR00001##

or an aromatic ring with functional groups shown by the following formula (II)

##STR00002##

wherein R.sub.1 is halogen (fluorine, chlorine, bromine, iodine), or a halogen-substituted alkane, cycloalkane, aldehyde group, carboxyl group, alkenyl group, alkynyl group, hydroxyl group, sulfonyl chloride, sulfonic acid bond or mercapto group, for interacting with a primary amino group. The compounds of the present invention can be universally bound to a variety of drugs to promote drug absorption and bioavailability, and reduce toxicity.

Embodiments herein are directed to moisturizing compositions comprising interpenetrating polymer networks, methods of making moisturizing compositions and methods of using moisturizing compositions.

The invention provides a hydrogen sulfide releasing polymer compound having a polysaccharide backbone, wherein the compound has at least two substructures, and wherein said substructures are capable of releasing hydrogen sulfide by thiol activation as well as uses thereof. Additionally, a method of treatment and prevention of a skin condition, an ocular disease or osteoarthritis is provided.

Core-shell microcapsules comprising a hydrophobic core surrounded by a shell comprising a thermosetting resin comprising moieties derived from polyisocyanates, substantially unprotonated chitosan and another amine different from chitosan, characterized in that the substantially unprotonated chitosan is delivered in the solid, powder form to the locus of the encapsulation reaction. The core-shell microcapsules are provided in the form of a slurry comprising 10 to 50 wt % of microcapsules, based on the total weight of the slurry, and the shell of the microcapsules comprises from 0.1 to 20 wt % of moieties derived from chitosan, based on the total weight of the shell.

The present invention relates to liquid compositions as well as the use of liquid compositions for differentially promoting the growth of the microbiome. The liquid composition forms a membrane of the invention when applied to the skin of a subject. The liquid composition as well as the membrane comprise chitosan or a salt thereof with a degree of acetylation of 20% or less and at least one further agent. The present invention further relates to pharmaceutical compositions for the treatment of dysbiosis.

The present invention relates to a cosmetic composition for molding, comprising a calcined layered double hydroxide and a polymer and, more specifically, to a cosmetic composition for molding and a preparation method therefor, the cosmetic composition comprising an active ingredient, a calcined layered double hydroxide, a polymer, and a solvent

Described herein, an anhydrous cosmetic composition includes one or more water-absorbing components; a malodour-controlling component; a cosmetically acceptable carrier; wherein the anhydrous cosmetic composition has a burst resistance pressure greater than about 137.9 mBar (2 psi); wherein the anhydrous cosmetic composition has a water vapor sorption per 100 g of the composition from about 2.0 g to about 15 g; and wherein the anhydrous cosmetic composition is essentially free of aluminium-based antiperspirant actives.

A cosmetic composition for treating acne includes at least one acne treatment active that includes at least one beta hydroxy acid and an aqueous carrier comprising at least one cationic polymer. In some embodiments the cosmetic composition is a cleanser that comprises at least one surfactant. When the composition is applied to a keratinous tissue it demonstrates deposition and retention of the beta hydroxy acid on the keratinous tissue after rinsing with water in an amount representing about at least 60% and up to about 250% greater as compared with an amount deposited using a composition that lacks the at least one cationic polymer.