Patent classifications
A61K8/738
METHOD FOR PREPARING A STABLE CONTROLLED-RELEASE PROPOLIS COLLOIDAL DISPERSION SYSTEM FOR VARIOUS USES
Method for preparing a stable controlled-release propolis colloidal dispersion system, wherein propolis is micronized and then dispersed in the solvent system, which is under stirring and consists of deionized water and either natural 1,3-propanediol or glycerol, in which deionized water hydroxypropyl--cyclodextrin or -cyclodextrin has been predissolved, and as the propolis/cyclodextrin/solvents system is under intense stirring for 30-45 min, a liposomal suspension is added thereto, and stirring is performed for 1 to 4 hours under continuous measurement of the total content in polyphenols and of the encapsulation efficiency %, until the specific parameters reach the desired values so that the stirring process is ended and the colloidal system is filtrated through suitable filters, its pH is adjusted and the size of dispersed particles as well as the release rate of the polyphenols of propolis in a buffer solution at pH 7.2 and 37 C. are measured and the colloidal system is stored.
METHOD FOR PRODUCING FLAVONOID INCLUSION COMPOUND
A method for producing a flavonoid inclusion compound, including a cleaving step including treating a sparingly soluble flavonoid having a rhamnoside structure with an enzyme having a rhamnosidase activity in the presence of a cyclodextrin to cleave a rhamnose. According to the production method of the present invention, a flavonoid inclusion compound and a composition of flavonoid glycosides having excellent solubility in water can be efficiently produced, so that the compound and composition can be suitably utilized in the fields of medicaments, foodstuff, health foods, foods for specified health use, cosmetics, and the like.
Antiperspirant and deodorant compositions
The present application relates to antiperspirant compositions comprising perfumes and sulfur-based perfume raw materials, and methods for making and using the antiperspirant compositions.
Anhydrous soft solid composition based on particles encapsulating a beneficial agent
Disclosed is an anhydrous composition comprising particles having a core containing a beneficial agent and an envelope surrounding the core. The envelope comprises a hydrophobically modified polysaccharide and a water-soluble carbohydrate and/or water-soluble polyol. The particles have a poured powder density from 300.0 g/l to 600.0 g/l and an absolute density of greater than 1.0. The composition also comprises a fatty phase comprising a solid fatty substance and an oil. The composition has a hardness measured at 32 C. at a humidity of 40% from 15 kPa to 150 kPa. Also disclosed are uses of the composition for caring for and/or for the hygiene of and/or for conditioning and/or for fragrancing and/or for making up a keratin material. The composition can be used for treating body odor wherein the composition comprises a deodorant active agent and/or antiperspirant active agent in free form and/or in encapsulated form.
Formulation and Process for Modulating Wound Healing
Methods and compounds are disclosed for wound healing by modulating autophagy. A formulation for modulating autophagy comprises a first modulating compound (FAM) selected from compounds having the general structure (I):
##STR00001## wherein: L represents a linker selected from CC, (a tolan), CHCH (a stilbene, preferably trans); or CR.sub.aCR.sub.b a stilbene derivative; where R.sub.a and R.sub.b are independently H or phenyl optionally substituted with (R.sup.3).sub.p or (R.sup.4).sub.q; R.sup.1 to R.sup.4 are independent substituents at any available position of the phenyl rings, preferably at 3, 3, 4, 4, and/or 5, 5; and m, n, p, and q are independently 0, 1, 2, or 3 representing the number of substituents of the rings, respectively, but at least one of m or n must be 1. Each R.sup.1 to R.sup.2 is independently selected from substituents described herein, including but not limited to hydroxyl, alkoxy, halo, halomethyl and glycosides. The formulation may also include an auxiliary autophagy modulating compound (AAM) as described herein. The formulation may include a hydrogel formed by the compounds themselves or otherwise and may include salts and/or complexes.
Grafting of cyclodextrin by amide bonds to an ether cross-linked hyaluronic acid and uses thereof
A hyaluronic acid product including a cross-linked hyaluronic acid and one or more cyclodextrin molecules. The hyaluronic acid is cross-linked by ether bonds, and the one or more cyclodextrin molecules are grafted onto the cross-linked hyaluronic acid by amide bonds, preferably using a triazine-based coupling reagent. A process of preparing a hyaluronic acid product including a cross-linked hyaluronic acid and one or more cyclodextrin molecules.
PERSONAL CARE COMPOSITIONS AND METHODS
Methods of making personal care compositions including microcapsules and methods of enhancing the efficacy of the microcapsules in said personal care compositions.
Method for producing flavonoid inclusion compound
A method for producing a flavonoid inclusion compound, including a cleaving step including treating a sparingly soluble flavonoid having a rhamnoside structure with an enzyme having a rhamnosidase activity in the presence of a cyclodextrin to cleave a rhamnose. According to the production method of the present invention, a flavonoid inclusion compound and a composition of flavonoid glycosides having excellent solubility in water can be efficiently produced, so that the compound and composition can be suitably utilized in the fields of medicaments, foodstuff, health foods, foods for specified health use, cosmetics, and the like.
Deodorant composition comprising a mixture of alpha, beta, and gamma cyclodextrin
This invention relates to an odour-absorbing composition comprising a mixture of -, -, and -cyclodextrins, wherein the amount of one of said -, -, and -cyclodextrins is equal to or higher than the total amount of the other two cyclodextrins.
Saponin-containing compositions for use in textile wipes and methods of use and preparation
The invention includes saponin-containing compositions, wipes impregnated with these compositions, and related methods. Specifically, the invention includes a cleansing and deodorizing composition that includes a saponin; a deodorizer; cyclodextrin and a solvent. The saponin may be derived from botanical sources, such as, for example, Sapindus mukorossi or trifoliatus. Also included are textiles that are impregnated with the composition of the invention. Such textiles may be, for example, made of biodegradable materials. The invention also includes related methods of use and treatment.