Disclosed herein are heart valves made from a polymeric material, such as silicone. Specifically exemplified are heart valve embodiments made from a one or two-pieces of material, or which have low thrombogenic potential. Also disclosed are methods of fabricating such valves. Furthermore, also disclosed are systems for testing performance of heart valves.

A valve body arrangement for a hydraulic or pneumatic valve comprises two elements between which a valve body is retained. The two elements are welded together in a first region, preferably by the laser transmission method, and clamp the valve body in a second region with a force.

Positive displacement using a connector with dual diaphragms is provided. For example, the connector includes a single fluid flow path, an air chamber and a valve. The single fluid flow path is configured for delivering fluid to a person and configured for receiving fluid from a person. The air chamber configured for expelling air from the air chamber when an actuator is inserted into the connector and for receiving air into the chamber when the actuator is removed from the connector. The valve plug comprises two diaphragms that separate the air chamber from the single fluid flow path. The valve plug is configured for creating positive displacement by returning the valve plug to its uncompressed state when the actuator is removed from the connector.

A heart valve prosthesis and delivery systems are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame includes a portion having a crimp that provides additional flexibility to the self-expanding frame in the collapsed configuration.

In some implementations, an apparatus includes a container having an exterior surface, having an interior surface and having a defect, a gasket positioned over the defect in the container, the gasket having a length, a width and a depth, a rigid patch positioned over the gasket, a plurality of pairs of studs and nuts positioned near the outer perimeter of the rigid patch, the studs being friction welded to the exterior of the container.

This invention relates to a combined ring rolling method for spherical valve body, which has the following procedures: 1) design for ring blank by computing ring blank volume and selecting reasonable rolling ratio according to the dimensions of forged ring; 2) design for rolling gap which includes the shapes and dimensions of working surfaces of main roll, mandrel and passive rolls according to the dimensions of ring blank and forged ring, the stable deformation condition of combined ring rolling and structure requirement of rolling equipment; 3) rolling forming with three stages of surface cross rolling, ring rolling and shaping by controlling of feeding speed of main roll and working positions of passive rolls. This invention has the technical economical advantages of low consumptions of energy and materials, high productivity and low production cost.

A prosthetic heart valve includes a base and a plurality of polymeric leaflets. Each leaflet has a root portion coupled to the base, and each leaflet has an edge portion substantially opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets. Each leaflet includes) at least two polymers along at least one portion of the leaflet, and each leaflet has a composition gradient of each of the at least two polymers along at least one portion of the leaflet.

An apparatus, system, and method are disclosed for optimizing a valve orifice shape. According to one representative embodiment, a method includes determining a specified relationship between a valve position and an output characteristic, and determining an orifice profile. The method also includes determining a relationship of an orifice area to the output characteristic. Further, the method includes shaping an orifice in a valve based on the orifice profile and the specified relationship between the valve position and the output characteristic. According to the method, the valve should approximately exhibit the specified relationship.

A bi-directional valve assembly, including valves for use in closed-ended catheters or other elongate tubular devices, is disclosed. In one embodiment, a catheter assembly for insertion into a body of a patient is disclosed and comprises an elongate catheter tube including an outer wall that at least partially defines at least one lumen that extends between a proximal end and a closed distal end thereof. The catheter tube includes a valve assembly that in turn includes a linear slit valve defined through the outer wall of a distal segment of the catheter tube, and a deformation region. The deformation region includes a compliant segment disposed in the outer wall of the catheter tube and a thinned portion of the outer wall. The compliant segment and thinned portion of the deformation region cooperate to preferentially deform the outer wall and open the slit valve during aspiration through the catheter tube.

A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.