A cosmetic ingredient, that consists of a solution of at least one extract of karanja oil including pongamol (CAS 484-33-3) and karanjin (CAS 521-88-0) in at least one solvent selected from the group of the diesters having the following formula (I), or mixtures thereof: ##STR00001## In which: n is from 0 to 19; R and R, which may be identical or different, are alkyls derived from an esterification by a linear or branched alcohol of molecular formula C.sub.xH.sub.2x+2O, x being from 1 to 30, from 1 to 20, and from 1 to 10. R is either a hydrogen atom or a C.sub.1-C.sub.3 alkyl group, which also relates to a process of selective precipitation, to a cosmetic formulation and also to the uses thereof.

The present invention provides a phenylpropanoid compound and a preparation method and use thereof. The phenylpropanoid compound has a structural formula shown as formula (I), and the pharmaceutically acceptable salt has a structural formula shown as formula (II), formula (III), formula (IV), or formula (V). The phenylpropanoid compound and the pharmaceutically acceptable salt thereof have an effect on inhibiting a content of an inflammatory cytokine NO and an expression of an inflammatory cytokine TNF-, have an effect on inhibiting a hydroxyl radical (OH), thereby have anti-inflammatory and antioxidant activities, and has a good application prospect in preparing of a medicine for treating an inflammatory disease related to the above factors, such as cervicitis, endometritis, pelvic inflammatory disease, mastitis, sphagitis and/or arthritis.

##STR00001##

The present invention provides a phenylpropanoid compound and a preparation method and use thereof. The phenylpropanoid compound has a structural formula shown as formula (I), and the pharmaceutically acceptable salt has a structural formula shown as formula (II), formula (III), formula (IV), or formula (V). The phenylpropanoid compound and the pharmaceutically acceptable salt thereof have an effect on inhibiting a content of an inflammatory cytokine NO and an expression of an inflammatory cytokine TNF-, have an effect on inhibiting a hydroxyl radical (OH), thereby have anti-inflammatory and antioxidant activities, and has a good application prospect in preparing of a medicine for treating an inflammatory disease related to the above factors, such as cervicitis, endometritis, pelvic inflammatory disease, mastitis, sphagitis and/or arthritis.

##STR00001##

A formulation comprising a variety of Chinese herbs is disclosed for the treatment of cancer and side effects associated with the treatment of cancer.

A formulation comprising a variety of Chinese herbs is disclosed for the treatment of cancer and side effects associated with the treatment of cancer.

A cosmetic ingredient, that consists of a solution of at least one extract of karanja oil including pongamol (CAS 484-33-3) and karanjin (CAS 521-88-0) in at least one solvent selected from the group of the diesters having the following formula (I), or mixtures thereof:

##STR00001##

In which: n is from 0 to 19; R and R, which may be identical or different, are alkyls derived from an esterification by a linear or branched alcohol of molecular formula C.sub.xH.sub.2x+2O, x being from 1 to 30, from 1 to 20, and from 1 to 10. R is either a hydrogen atom or a C.sub.1-C.sub.3 alkyl group, which also relates to a process of selective precipitation, to a cosmetic formulation and also to the uses thereof.

The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compoundsFree-B-ring flavonoids and flavansfor use in the prevention and treatment of diseases and conditions mediated by the COX-2 and 5-LO pathways. The present invention further provides a novel method for simultaneously inhibiting the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) enzymes, and reducing cox-2 mRNA production. Finally, the present invention includes a method for weight loss and blood glucose control. The methods of this invention are comprised of administering to a host in need thereof an effective amount of the composition of this invention together with a pharmaceutically acceptable carrier. This invention relates generally to the prevention and treatment of diseases and conditions mediated by the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) pathways, including but not limited to the relief joint discomfort and pain associated with conditions such as osteoarthritis, rheumatoid arthritis, and other injuries that result from overuse.

The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compoundsFree-B-ring flavonoids and flavansfor use in the prevention and treatment of diseases and conditions mediated by the COX-2 and 5-LO pathways. The present invention further provides a novel method for simultaneously inhibiting the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) enzymes, and reducing cox-2 mRNA production. Finally, the present invention includes a method for weight loss and blood glucose control. The methods of this invention are comprised of administering to a host in need thereof an effective amount of the composition of this invention together with a pharmaceutically acceptable carrier. This invention relates generally to the prevention and treatment of diseases and conditions mediated by the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) pathways, including but not limited to the relief joint discomfort and pain associated with conditions such as osteoarthritis, rheumatoid arthritis, and other injuries that result from overuse.

The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compoundsFree-B-ring flavonoids and flavansfor use in the prevention and treatment of diseases and conditions mediated by the COX-2 and 5-LO pathways. The present invention further provides a novel method for simultaneously inhibiting the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) enzymes, and reducing cox-2 mRNA production. Finally, the present invention includes a method for weight loss and blood glucose control. The methods of this invention are comprised of administering to a host in need thereof an effective amount of the composition of this invention together with a pharmaceutically acceptable carrier. This invention relates generally to the prevention and treatment of diseases and conditions mediated by the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) pathways, including but not limited to the relief joint discomfort and pain associated with conditions such as osteoarthritis, rheumatoid arthritis, and other injuries that result from overuse.

The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compoundsFree-B-ring flavonoids and flavansfor use in the prevention and treatment of diseases and conditions mediated by the COX-2 and 5-LO pathways. The present invention further provides a novel method for simultaneously inhibiting the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) enzymes, and reducing cox-2 mRNA production. Finally, the present invention includes a method for weight loss and blood glucose control. The methods of this invention are comprised of administering to a host in need thereof an effective amount of the composition of this invention together with a pharmaceutically acceptable carrier. This invention relates generally to the prevention and treatment of diseases and conditions mediated by the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) pathways, including but not limited to the relief joint discomfort and pain associated with conditions such as osteoarthritis, rheumatoid arthritis, and other injuries that result from overuse.