A61K2800/434

HOMOGENEOUS PERSISTENT LUMINESCENCE NANOCRYSTALS AND METHODS OF PREPARATION AND APPLICATION THEREOF
20180244992 · 2018-08-30 ·

This invention provides a groundbreaking approach to PLNPs and their preparation. In particular, the synthetic methodology disclosed herein fundamentally differs from the traditional solid-state annealing reactions that require extreme and harsh reaction conditions. In one unique aspect of the invention, a simple, one-step mesoporous template method utilizing mesoporous silica nanoparticles (MSNs) is disclosed that affords in vivo rechargeable NIR-emitting mesoporous PLNPs with uniform size and morphology. In another unique aspect of the invention, the novel synthetic approach is based on aqueous-phase chemical reactions conducted in mild conditions, resulting in uniform and homogeneous PLNPs with desired size control (e.g., sub-10 nm).

Non-Mutagenic Photochromic Dye
20180221262 · 2018-08-09 ·

A method of solubilizing a composition, such as an organic manufactured photochromic dye that is free of carcinogens, non-mutagenic, non-toxic to human skin in any concentration, and suitable for application to, and absorbable by, human skin. The photochromic dye is suitable to be applied directly to human skin, and which dye is configured to indicate exposure to UV rays. The composition is configured to change color upon exposure to UVA, UVB and/or UVC rays. The composition can be used with other compositions, such as sunscreen, and be applied to human skin prior to application of the sunscreen, or, formulated with the sunscreen such that when the active ingredients of the sunscreen diminish, the photochromic dye will change color to generate a visual indicator of this condition.

TEETH WHITENING COMPOSITIONS AND METHODS
20180221261 · 2018-08-09 ·

Disclosed herein are teeth whitening compositions generally including an oxidizing agent (e.g., a peroxide), and an activating agent that has an emission wavelength between about 400 nm and about 570 nm (e.g., Eosin B). Methods of employing these compositions to whiten teeth, methods of making these compositions and kits that include some or part of the composition ingredients, are also described.

Method of stabilizing riboflavin

A method of stabilizing riboflavin by affixing the riboflavin to at least one substrate for the riboflavin by covalent bonding, hydrogen bonding, Van der Waals forces, or a combination thereof, to form an optically-activated complex, is provided. When activated by absorption of light in the ultraviolet (UV) to visible region of the electromagnetic spectrum the riboflavin in the complex re-emits light of longer wavelength in the blue-green-yellow region of the electromagnetic spectrum.

Whitening Dentifrice Compositions with Zinc Core Shell Silica Particles

A whitening dentifrice composition, free from peroxide whitening agents, includes a blue coloring agent, a zinc core shell silica (Zn-CSS) particle, and an orally acceptable vehicle including a non-aqueous solvent and water. The blue coloring agent includes at least one of a blue pigment and a blue dye and has a blue to blue-violet color with a hue angle in the CIELAB system ranging from 200 degrees to 320 degrees. The Zn-CSS particle includes a silica core, and a surface of the silica core etched with a metal silicate, which is a silicate of zinc ion and optionally a monovalent metal ion.

ASSEMBLY AND PROCESS FOR MAKING UP A KERATIN MATERIAL
20180140519 · 2018-05-24 · ·

The present invention relates to an assembly for making up a keratin material, in particular the nails, the lips, the eyelids, the eyelashes, the eyebrows or the contour of the eyes, comprising at least: a first composition intended to be applied to the keratin material, the first composition being a composition that is capable of forming a reflective coat, a second composition intended to be applied onto the first composition, said second composition being a translucent and coloured composition. The present invention also relates to a makeup process.

Method for evaluating state of horny layer and method for evaluating horny layer improvement effect of cosmetic preparation
09970848 · 2018-05-15 · ·

The invention relates to providing a method for more conveniently evaluating stratum corneum condition. A stratum corneum sheet is contacted with a solution of a water-soluble dye, and the staining intensity or fluorescence intensity is measured to allow convenient evaluation of the stratum corneum condition. There is further provided a method for evaluating the ameliorating effect of a cosmetic or cosmetic treatment on the stratum corneum, by implementing the method for evaluating stratum corneum condition using a water-soluble dye according to the invention.

TEETH WHITENING COMPOSITIONS AND METHODS
20180125770 · 2018-05-10 ·

Disclosed herein are teeth whitening compositions generally including an oxidizing agent (e.g., a peroxide), and an activating agent that has an emission wavelength between about 400 nm and about 570 nm (e.g., Eosin B). Methods of employing these compositions to whiten teeth, methods of making these compositions and kits that include some or part of the composition ingredients, are also described.

EMISSIVE POLYMERIC MATRICES

The present disclosure relates to emissive polymeric matrices and methods of using them. The emissive polymeric matrices comprise a monomer such as, for example, 2-hydroxyehtyl methacrylate (HEMA) and at least one chromophore.

Optically-activated system for reducing the appearance of skin imperfections

Optically-activated systems and methods for reducing the appearance of dark under eye circles are provided. The systems comprise a complex of a fluorescent compound and a substrate for the fluorescent compound which are affixed to one another by covalent bonding, hydrogen bonding, Van der Waals forces, or a combination thereof. After absorption of ambient light, the fluorescent compound in the complex re-emits visible light of longer wavelength. The re-emitted light provides an illuminating radiant effect and is particularly useful in improving the appearance of skin imperfections.