Described herein is a method of treating the hair. The method includes applying to the hair a hair treatment composition including one or more fluorescent compounds and rinsing the hair with water. The one or more fluorescent compounds each include a fluorophore, one or two permanent cations, and one to four incipient cations. The incipient cations are pendant to the core structure and are neutral. The one or more fluorescent compounds enter the hair shaft after the hair treatment composition is applied to the hair. The hair treatment composition has a pH of from about 7 to about 11. The pH of the hair after rinsing is from about 3.5 to about 6. The rinsing of the hair causes one or more of the one to four incipient cations to change from neutral to positively charged inside of the hair shaft.

The invention relates to process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid water-insoluble particulate matter with a cationic additive in an aqueous medium to obtain a dispersion of said particulate matter having a positive zeta potential; (b) coating the solid water-insoluble particulate matter by precipitation of a metal oxide salt onto the surface of the particulate matter, forming a metal oxide layer thereon; and (c) aging said coating layer. The invention further relates to coated particulate matter obtained by the process and to compositions comprising solid, water-insoluble particulate matter, coated by a metal oxide layer, the particulate matter being a dermatological active agent or a pesticide. The invention additionally relates to methods of treating a surface condition in a subject using compositions comprising solid, water insoluble dermatologically active agent, coated by a metal oxide layer.

The disclosure relates to a composition that is designed to be administered to a subject intradermally for treating pigmentless skin or creating a temporary tattoo. The composition comprises particles having a polymeric shell and a core that includes a coloring agent. The particles are in a carrier solution at a concentration that is cosmetically effective to delay the bioabsorbance and/or biodegradation of coloring agent in a subject's skin. Bioabsorbance and/or biodegradation of the particles fades the tattoo until it is no longer visible.

A method of solubilizing a composition, such as an organic manufactured photochromic dye that is free of carcinogens, non-mutagenic, non-toxic to human skin in any concentration, and suitable for application to, and absorbable by, human skin. The photochromic dye is suitable to be applied directly to human skin, and which dye is configured to indicate exposure to UV rays. The composition is configured to change color upon exposure to UVA, UVB and/or UVC rays. The composition can be used with other compositions, such as sunscreen, and be applied to human skin prior to application of the sunscreen, or, formulated with the sunscreen such that when the active ingredients of the sunscreen diminish, the photochromic dye will change color to generate a visual indicator of this condition.

The present disclosure provides silicone-based biophotonic compositions and methods useful in phototherapy. In particular, the silicone-based biophotonic compositions of the present disclosure include a silicone phase and a surfactant phase, wherein the surfactant phase comprises at least one chromophore solubilized in a surfactant. The silicone-based biophotonic compositions and the methods of the present disclosure are useful for promoting wound healing and scarring, as well as various other skin disorders.

The present disclosure provides biophotonic compositions containing halogen ions and/or halogen salts and methods useful in phototherapy. In particular, the biophotonic compositions comprising halogen of the present disclosure include at least one chromophore; and halogens and/or halogen salts such KI, or KCl, or KBr, or CsBr, or MgBr.sub.2, or ZnBr.sub.2, or NaF, or NaCl, or NaBr, or I.sub.2, or I.sub.3.sup., or Br.sub.2, or Cl.sub.2. The biophotonic compositions and the methods of the present disclosure are useful for promoting tissue repair, wound healing, bone regeneration and skin rejuvenation, as well as treating oral diseases, microbial and viral infections, acne and various other skin disorders and various orphan diseases.

An object of the present disclosure is to investigate fluorescent substance being safe and having a high color developing property, and obtain an inorganic red fluorescent substance consisting of an element which exerts no bad influence upon human bodies.

A cosmetic containing inorganic particles consisting of a compound represented by a general formula:

Mg.sub.xTi.sub.yO.sub.(x+2y+2z):Mn.sup.4+.sub.z

wherein 1.5<x<2.5, 0.5<y1.5, and 0.0001<z<0.1.

A method of solubilizing a composition, such as an organic manufactured photochromic dye that is free of carcinogens, non-mutagenic, non-toxic to human skin in any concentration, and suitable for application to, and absorbable by, human skin. The photochromic dye is suitable to be applied directly to human skin, and which dye is configured to indicate exposure to UV rays. The composition is configured to change color upon exposure to UVA, UVB and/or UVC rays. The composition can be used with other compositions, such as sunscreen, and be applied to human skin prior to application of the sunscreen, or, formulated with the sunscreen such that when the active ingredients of the sunscreen diminish, the photochromic dye will change color to generate a visual indicator of this condition.

The invention generally relates to fluorescent particles and more specifically to silica-based fluorescent nanoporous particles with physically encapsulated organic dyes. In one aspect of the invention, the nanoporous architecture provides a significant enhancement in fluorescence of the particles brightness compared to free dye. A particular chemical control of the silica matrix prevents the dye molecules from leaking the particles.

The present disclosure provides biophotonic materials and methods useful in phototherapy. In particular, the biophotonic materials of the present disclosure include a cohesive matrix, and at least one chromophore, wherein the at least one chromophore can absorb and emit light from within the biophotonic material. The biophotonic materials and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various skin disorders.