A method, system, and apparatus for providing sterilization, decontamination, and therapeutic treatment may be provided. These may include a misting, vaporizing, spraying, foaming or other dispensing apparatus to cover a person, a surface, and enclosure, a room or other structure with an antimicrobial solution. Radiation sources, such as lights, may be utilized to expose the antimicrobial solution to a certain wavelength of radiation. The combination of the antimicrobial solution and the certain wavelength of radiation may create a synergistic reaction that causes an effect greater than the radiation or solution separately. A container or passageway including an apparatus dispensing a solution so that an object or person is saturated with an antimicrobial solution. The person or object is then exposed to a certain wavelength of radiation that creates a synergistic reaction between the solution and the radiation.

A portion of a treatment device for treating bacteria may be coupled with the bacteria through direct or indirect contact. Mechanical stress energy and electromagnetic energy are generated with the treatment device, and are transmitted from the treatment device to the bacteria during the coupling. The bacteria are treated with both the mechanical stress energy and the electromagnetic energy to produce a killing effect on the bacteria. A treatment device may include a mechanical stress energy emitting portion, an electromagnetic energy emitting portion, and a contacting portion for coupling into direct or indirect contact with the bacteria and transmitting mechanical stress energy to the bacteria during the coupling. The mechanical stress energy emitting portion and the electromagnetic energy emitting portion are operable to treat the bacteria with a combination of mechanical stress energy and electromagnetic energy to produce a killing effect on the bacteria.

Disclosed are compounds of general formula (I):

##STR00001##

and pharmaceutically acceptable salts thereof, formulations, methods and uses in, for example, the treatment of disease.

A method and device are presented for providing patient safe light to a wound. The device includes a radiation source producing flora lethal radiation wavelengths, a radiation conduit detachably optically coupled to the radiation source, and a patch remotely located from the radiation source configured to at least partially conform to a surface contour of the wound. The patch includes a flexible panel formed of a radiation transmitting material able to withstand sterilization, including at least one surface with a disturbed surface area configured to emit radiation upon the wound.

An extracorporeal blood disinfection system (10) includes an input tube (12) forming a flowpath (22) for infected blood from a mammalian patient (11); a disinfection unit (14) including a microbicidal light emitting device (24) emitting a plurality of light emissions, each light emission having a wavelength in a range between about 380 to about 800 nm; a treatment flowpath (22) in communication with the input tube (12) that is substantially transparent to emitted light of the microbicidal light emitting device (24) for receiving at least a portion of the infected blood flow therethrough, wherein the microbicidal light emitting device (24) effectuates a dose of light emissions to the infected blood in the treatment flowpath (22) to disinfect the blood; and an output tube (16) fluidly and physically connected wherein material can flow within the treatment flowpath forming a flowpath the disinfected blood flow from the disinfection unit to the patient.

Disclosed are compounds of general formula (I): ##STR00001##
and pharmaceutically acceptable salts thereof, formulations, methods and uses in, for example, the treatment of disease.

An ultraviolet light-emitting phosphor having excellent degradation resistance and emission intensity is provided. The ultraviolet light-emitting phosphor is a phosphor comprising yttrium element, scandium element, aluminum element and oxygen element, which is excited by irradiation of vacuum ultraviolet rays or electron beams to emit ultraviolet rays.

A skin microbiota modulation device that includes a cold plasma assembly configured to generate a cold plasma stimulus including a partially ionized gas mixture and to interrogate a biological surface with the cold plasma stimulus; and a microbiota seeding assembly including one or more target species of micobiota, the microbiota seeding assembly configured to deliver the one or more target species of micobiota to the biological surface.

The device (3) comprises a first duct (14) having a proximal end, associated with a hand-piece (5), and an open distal end (14A). The first duct (14) is in fluid communication with an inlet port (18) for a liquid containing scattering particles. The device (3) furthermore comprises a light guide (7) so arranged and configured as to convey a laser radiation coming from a laser source (11) near the open distal end (14A) of the first duct (14).

A method for the antifungal treatment of a turf includes a step of applying blue light on said turf.