A method for generating, within a conduit, discrete volumes of one or more fluids that are immiscible with a second fluid. The discrete volumes can be used for biochemical or molecular biology procedures involving small volumes, for example, microliter-sized volumes, nanoliter-sized volumes, or smaller. The discrete volumes are separated from one another by a liquid that is immiscible with the fluid(s) of the discrete volumes, for example, aqueous immiscible-fluid-discrete volumes separated by an oil.

Embodiments of a tie plate sorter are disclosed wherein the tie plates are sorted and fed to an output device for further feeding to a tie plate distribution system. The tie plates may be oriented as needed. Exemplary methods are also provided.

A pumping system comprising a pump comprising a door for access within a housing of the pump, a pump segment configured for conveying a fluid based on compression of the pump segment, a pump segment frame for preventing said pump segment from stretching, a visual placement indicator configured for facilitating in a proper placement of the pump segment frame in the housing, and a non-pinching valve configured to be disposed in the housing and to control a flow of the fluid without requiring pinching of a tube.

A supply system with a plurality of consumers, which can be supplied with a minimum volumetric flow by the supply system to ensure their operational function, wherein the supply system exhibits a network of lines with a plurality of lines, which are each hooked up to the consumers, and a pump connected to the lines for generating a volumetric flow of supply fluid in the lines, wherein the supply system incorporates a network of lines in which consumers are fluidically connected in parallel in relation to the pump arrangement, and wherein each consumer has allocated to it at least one flow control valve functionally placed upstream from the respective consumer in the cooling circulation as viewed from the position of the pump in the direction of flow.

A variable-capacity compressor that includes a housing having an inlet for receipt of refrigerant and an outlet for return of refrigerant, and a plurality of compressing elements contained in the housing between the inlet and the outlet. The variable capacity compressor includes a valve having an electrical control. The valve is dedicated to fewer than all of the compressing elements. The valve is movable between a first state which communicates refrigerant flow to the compressing elements, and a second state that reduces or stops flow to the compressing elements. In an embodiment of the invention, an unloading controller has an operational modulation mode that includes cycling the valve between on and off states to provide a portion of compressor capacity. The unloading controller is further programmed to provide a minimum delay time between transitions between the first and second states, but no maximum dwell time between transitions.

A pumping system comprising a pump comprising a door for access within a housing of the pump, a pump segment configured for conveying a fluid based on compression of the pump segment, a pump segment frame for preventing said pump segment from stretching, a visual placement indicator configured for facilitating in a proper placement of the pump segment frame in the housing, and a non-pinching valve configured to be disposed in the housing and to control a flow of the fluid without requiring pinching of a tube.

A solvent delivery system for a liquid chromatography system may include a first gradient proportioning valve in fluidic communication with a first plurality of sources of solvent and producing therefrom a first low-pressure gradient stream. The solvent delivery system may further include a second gradient proportioning valve in direct fluidic communication with an inlet of the first gradient proportioning valve and with a second plurality of sources of solvent, the second gradient proportioning valve producing a second low-pressure gradient stream from the second plurality of sources of solvent, wherein one solvent source of the first plurality of sources of solvent used by the first gradient proportioning valve to produce the first low-pressure gradient stream comprises the second low-pressure gradient stream. The solvent delivery system may also include a first pump in direct fluidic communication with the first gradient proportioning valve to receive and pressurize the first low-pressure gradient stream.

A water tempering system comprising a mixing tank located downstream from the main hot water storage tank, the mixing tank receiving a supply of hot water at a first temperature and a supply of cold water, the hot water and cold water supplies mixing within the mixing tank to provide a source of tempered hot water at a reduced, second temperature that is discharged from the mixing tank for distribution and use within an overall system. The amount of cold water directed to the mixing tank is controlled by a variable frequency drive pump which can adjust depending on system demands to ensure that sufficient cold water is directed to the mixing tank to ensure adequate mixing occurs to bring the temperature of the hot water to the second reduced temperature even during periods of low demand.

A disposable device for the sterile transfer of fluids, such as liquids or gases, includes a body, a bore formed through at least a portion of the interior of the body, and a linearly moveable plunger contained within the bore. The body is formed from a rotating section and a stationary section. Partial rotation of the rotating section around a portion of the stationary section and the plunger drives the plunger linearly within the bore, opening and closing the device. The plunger includes at least a first and a second opening, and a fluid channel in the interior of the plunger connecting the first and second openings forming a fluid pathway to downstream components when the device is open. A termination component at one end of the plunger connects to a downstream component. A flange at one end of the body attaches to an upstream component. When the device is closed, the upstream end of the plunger is in alignment with the upstream flange of the body, forming a steamable sterilized in place face and a sterile barrier.

A liquid chromatography system includes a gradient proportioning valve in fluidic communication with sources of solvent. From the solvent sources, the gradient proportioning valve produces a low-pressure gradient stream. A first pump is in fluidic communication with the gradient proportioning valve to receive, pressurize, and move the pressurized low-pressure gradient stream to a flow-combining device. A second pump operates in parallel with the first pump and moves a pressurized solvent stream to the flow-combining device where the pressurized solvent stream combines with the low-pressure gradient stream to produce a high-pressure gradient stream. A second gradient proportioning valve can produce, from a second plurality of sources of solvent, a second low-pressure gradient stream, wherein the solvent stream moved by the second pump to the flow-combining device and combined with the other low-pressure gradient stream comprises the second low-pressure gradient stream.