A system for creating an arteriovenous (AV) fistula comprises a vessel access sheath having a hollow interior and an exit port, a side access needle catheter configured to fit within the hollow interior of the sheath, a needle configured to be inserted into a blood vessel through the side access needle catheter, a toggle delivery catheter configured to fit within the hollow interior of the sheath, and a toggle apparatus configured to be delivered into a vessel through the toggle delivery catheter. The toggle apparatus comprises a shaft and a toggle member pivotably attached to a distal end of the shaft. A source of RF energy or resistive heat energy may be provided for application to the toggle member and/or to a heater insert in the toggle delivery catheter, for the purpose of creating the fistula.

A method of inducing retrograde blood flow may include extending a sheath through opposite walls of one of an artery and a vein of a subject and through a wall of the other of the artery and the vein such that a distal end of the sheath may be positioned within one of the artery and the vein. The method may include inducing retrograde blood flow in the artery and delivering the induced retrograde blood flow into the vein of the subject via the sheath.

A delivery system for delivering an implant to a first space within a body of a patient including an elongate delivery member having a proximal portion, a distal portion, a lumen and a receiving area, the receiving area dimensioned for receipt of the implant. A deforming member is movable with respect to the delivery member from a first position to a second position to apply a force to the implant to deform the implant positioned in the receiving area of the delivery member.

A vein cover that can reduce or prevent intimal thickening by delivering blood to the downstream veins while gradually buffering the blood pressure, pulse pressure, and blood flow rate of the blood flowing through the lumen is provided.

A cylindrical vein cover (10) is to be placed outside a vein (4) that is anastomosed to an artery (3) or to an artificial vessel (5), and has a portion (A) that has a 10% elastic index of 25 N or less when the inner diameter of the vein cover (10) is expanded by 10% from its natural state.

An implantable perfusion device (2) comprises a tubular transmission line (4) with an inlet end (6), an outlet end (8) and a flow restriction element (10) located therebetween, whereby an inlet section (12) of the transmission line is defined between the inlet end and the flow restriction element and whereby an outlet section (14) of the transmission line is defined between the flow restriction element and the outlet end. Moreover, the device comprises a perfusion chamber (16) containing a load of biologically active cells and is provided with a fluid entrance (18), a fluid exit (20) and a chamber volume (22) formed therebetween. The fluid entrance comprises at least one first microchannel platelet (24) and the fluid exit comprises at least one second microchannel platelet (26), each one of the microchannel platelets comprising at least one array of microchannels (28) defining a fluid passage between respective external and internal platelet faces, the microchannels having an opening of 0.2 to 10 μm. The fluid entrance (18) of the perfusion chamber is in fluid communication with the inlet section (12) of the transmission line; and the flow restriction element (10) is configured to establish a predetermined pressure excess in the inlet section (12) versus the outlet section (14).

In examples described herein, a system includes an elongate member configured to be introduced into vasculature of a patient. The elongate member includes a pressure sensor configured to generate a pressure signal indicative of pressure in the vasculature adjacent the needle. The system includes processing circuitry configured to receive the pressure signal from the pressure sensor, detect, based on the pressure signal, dislodgment of the elongate member from the vasculature, and generate an output in response to detecting the dislodgment of the elongate member from the vasculature.

Various implementations include an arteriovenous graft device. The device includes an outer conduit and an inner conduit. The outer conduit has a first outer conduit end and a second outer conduit end opposite the first outer conduit end. The first outer conduit end defines an outer conduit opening extending from the first outer conduit end to the second outer conduit end. The first outer conduit end is configured to be in fluid communication with an artery and the second outer conduit end is configured to be in fluid communication with a vein. The inner conduit defines an inner conduit opening. The inner conduit is sized to be disposed within the outer conduit opening. The inner conduit is movable between a collapsed position and an expandable position.

A protection cover (1) for an anastomotic part in which a first blood vessel is joined to a second blood vessel, having a tubular portion (2) that is configured to cover an outside of the first blood vessel, and a planar portion (4) that is configured to cover an outside of the second blood vessel, the protection cover (1) comprising a knitted fabric which is formed from continuous yarn extending from the tubular portion (2) to the planar portion (4).

A system for preventing thrombosis in an implantable medical device includes an implantable medical device sized for implantation at least partially within a patient's body. The device includes an at least partially electrically conductive portion that is disposed within a patient's body upon implantation, an electrode coupled to the electrically conductive portion of the device; and a power source coupled to the electrode. The power source provides a negative electric charge to the at least partially electrically conductive portion for an indefinite period of time. The device may be configured to resist thrombosis, infection, and/or undesired tissue growth via the charged conductive portion once implanted. Exemplary embodiments of the implantable medical device include a hemodialysis vasculature graft, a dialysis catheter, a coronary artery, and a heart valve.

A fistula bandage comprising a bandage and an adjustment device for adjusting a tension of the bandage, where the adjustment device comprises: a first engagement portion connected to a first end of the bandage; and a second engagement portion connected to a second end of the bandage; wherein the second engagement portion comprises: a base having a first sliding slot and connected to the second end of the bandage; a moving member slidingly engaged with the base and connected to the first engagement portion; a driving mechanism supported on the base and driving the moving member to slide in a first direction relative to the base; and a stopping mechanism connected to the driving mechanism. The driving mechanism drives the first engagement portion to move relative to the second engagement portion, thereby achieving the purpose of adjusting the tension of the bandage.