A pump having two pistons which are parallel and in opposition and are disposed in two, cylindrical, cavities in a pump body, including at least one inlet port and at least one outlet port connected to a rotational port-switching device which can move axially along its rotational axis and is held in abutment in the pump body by a restoring member, in the form of a spring.

Ambulatory infusion pumps, medicament reservoirs, and medicament sealing assemblies, including a variety of trocar seal assemblies and fill plug seal assemblies, plus related components, as well as component combinations and related methods.

A pump suitable for use in a wearable medical device, such as a patch pump, comprises an axially translatable chamber with an inlet and an outlet, a piston or a diaphragm rotatably received in the chamber, a first valve between the inlet and the chamber, a second valve between the outlet and the chamber, a cam affixed to the chamber, a follower affixed to the piston and in contact with the cam for axially translating the chamber, and a biasing means acting on the chamber for applying a force on the chamber in an axial direction of the chamber to maintain such contact.

A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula.

A fluid dispensing device includes a container coupled between a bottle and a discharge tube for forcing the fluid to flow through the discharge tube without gravity, a base member is disposed in the container, a housing is engaged in the container and movable toward and away from the base member, a spring biased plug controls the fluid to flow out of the housing, a cap and a casing are attached to the container, a spring biased valve piece is engaged in the casing for engaging with the cap and for controlling the fluid to flow through the cap, a magnetic member is attached to the casing, and a coil is attached to the container to act with and to move the magnetic member in the container.

Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.

An injection apparatus for sequentially injecting a patient with at least two medicaments may include a hand-held unit comprising a grip for being held by an operator, a single needle, a base unit coupled to the hand-held unit via at least one connecting tube, at least two containers for holding medicaments removably coupled to the base unit, and at least one pump. The at least one connecting tube can be flexible enough to enable easy maneuvering of the hand-held unit and rigid enough to prevent widening of the tube due to inner pressure when medicaments pass from the containers to the hand-held unit. The injection apparatus can be used to administer the at least two medicaments sequentially at different injection points.

A device (100) for delivering a medicament into a patient's body by injection into or through the patient's skin, including: a main body having a bottom enclosure (104) that has a top surface including a button guide latch (268); a reservoir (160) disposed within the main body for containing the medicament; an injection needle (152) for penetrating the skin of the patient, the needle (152) having a lumen and communicating with the reservoir (160) when the device (100) is activated; a pressurizing system (140, 144) for pressurizing the reservoir (160) when the device (100) is activated; and an activator button (128) movably disposed on the main body and movable from a pre-activated position to an activated position. The activator button (128) includes an activation arm (228). When the activator button (128) moves from the pre-activated position to the activated position, an end of the activation arm (228) engages with the button guide latch (268) and prevents return movement of the activator button (128).

A system for delivering to a patient a slurry which includes a fluid and a material that is non-dissolvable or immiscible in the fluid. The system includes a container adapted to contain the slurry and a supernate of the slurry, a syringe adapted to contain the slurry after dilation with the supermate, a fluid path between the syringe and the contents of the container, the fluid path including a needle at least partially disposed within the contents of the container, a plunger disposed in the syringe and adapted to create pressure in the syringe to cause a dilated slurry to flow into the syringe through the fluid path, and a fluidizing systen associated with the container and comprising a holder adapted to move the needle within the container to affect dilation of the slurry with a portion of the supernate.

Apparatus and methods of dispensing fluid intravenously to a subject, and of flushing a line of an intravenous fluid administration apparatus, are provided. The apparatus may include a reservoir pump configured to operate in fluid communication with an upstream source of a first fluid and a downstream pressure-operated valve. The reservoir pump may also be configured to, during operation, automatically refill itself with the first fluid from the first upstream source. The downstream pressure-operated valve may be configured to operate in fluid communication with the reservoir pump and a second fluid source upstream of the pressure-operated valve, and to, during operation, dispense the first fluid to tubing downstream of the pressure-operated valve based on a pressure condition within the pressure-operated valve exceeding a threshold pressure.