An intradermal fluid delivery device that uses a processor controlled electromechanical delivery mechanism is provided. An air pump pushes fluid containing medication or saline from a fluid compartment through a microneedle array into a person's skin. The processor repeatedly turns the air pump on or off, for the fluid to gradually be injected into the person's skin. The processor may be configured to control the total fluid delivery time as well as the granularity of the fluid delivery. The total fluid delivery time may be set to T, and the time period T may be divided into smaller periods t.sub.1 to t.sub.n, where the fluid may be administered in a period t1, the fluid delivery may then be stopped for a period t2, followed by another fluid delivery period, etc. The periods t1 to tn may be the same or of different lengths.

A method of testing the rotor engagement of a peristaltic pump rotor. The method comprising steps of providing a pump system comprising a peristaltic pump rotor; a tube; a valve; a pressure sensor; a comparator; and a processor. The pressure sensor is configured to monitor the pressure in a fluid in the tube downstream of the peristaltic pump rotor and upstream of the valve. The comparator is configured to continuously monitor the pressure sensor and compare the measured fluid pressure data with a predetermined parameter. The processor is configured to receive a signal from the comparator and generate an alert signal when the measured pressure data falls outside the predetermined parameters.

The present invention relates to a disposable delivery assembly for a drug delivery device to dispense a liquid medicament, the delivery assembly comprising: a disposable injector comprising an injection needle, a flexible tube and an injector fluid coupling, wherein the injection needle is in fluid communication with the fluid coupling via the flexible tube, a disposable cartridge comprising a reservoir at least partially filled with the liquid medicament and comprising a cartridge fluid coupling in fluid communication with the reservoir, wherein the injector and the cartridge are mechanically interconnected in an undeployed configuration, in which the injector fluid coupling and the cartridge fluid coupling are disconnected, and wherein the cartridge is displaceable relative to the injector into a deployed configuration, in which the injector fluid coupling and the cartridge fluid coupling are in fluid communication.

The present disclosure provides a drug discharge assembly including a drive piece linearly reciprocated along one direction, a rotating unit being in contact with an end of the drive piece and rotating in one direction according to a linear reciprocating motion of the drive piece, a flexible tube disposed adjacent to the rotating unit and having a curved section at least partially extending in a circumferential direction, and a pressing unit mounted on the rotating unit and rotating while pressing the tube according to a rotation of the rotating unit, and a drug injection device comprising the same.

A peristaltic pump has an arcuate raceway with a partially concave inner surface extending through an arc of at least one hundred eighty degrees (180°). The arc defines a midpoint, and a rotor faces the inner surface of the raceway and is both rotatable relative to the raceway and translationally movable relative to the raceway between a pump position, wherein the rotor is spaced from the midpoint a first distance, and a tube load position, wherein the rotor is spaced from the midpoint a second distance greater than the first distance. A motor is coupled to the rotor to rotate the rotor plural are rollers arranged on the rotor to contact tubing disposed between the rotor and the raceway when the rotor is in the pump position. The motor is prevented from stopping at a predetermined angular position to facilitate loading and unloading tubing.

A dispenser includes a container with an endwall and a cap covering the endwall. The cap has an aperture and a first film covering the aperture. A hood over the cap has a barrel defining a bore which is coaxially aligned with the aperture, a second film sealing the bore, and a gasket compressed behind the second film. A spike is carried for movement in the barrel between retracted and advanced positions. The dispenser has first and second conditions. In the first condition, the first and second films are against each other and seal the aperture and barrel, and in the second condition, the first and second films are away, unsealing the aperture and the barrel. When the dispenser is in the second condition and the spike moves from the retracted position to the advanced position, the spike pierces the endwall.

Embodiments are provided for dynamic management of charge. A method involves obtaining an estimated readiness time for an energy storage element, obtaining a target state of charge for the energy storage element, calculating an estimated charging time based at least in part on a difference between the target state of charge and a current state of charge, using a first charging rate to charge the energy storage element to an intermediate state of charge responsive to determining a time difference between the estimated readiness time and a first time is greater than the estimated charging time, maintaining the energy storage element at the intermediate state of charge, and responsive to determining a time difference between the estimated readiness time and a second time is less than the estimated charging time, using a second charging rate to charge the energy storage element to the target state of charge.

A peristaltic pump actuator includes a rotor element supporting rollers, the rotor element being configured to rotate about a rotor axis and the rollers each being configured to rotate about a roller axis that is parallel to the rotor axis. The rotor element and each of the rollers is constrained such that the rotor element and rollers are able to rotate only about their respective axes. A shoe having a displacement axis perpendicular to the rotor axis is forced against the rollers by an urging element without rotation in any axis. A tube may be placed between the shoe and the rollers.

A waste-reducing pumping system and method for delivering a liquid to a patient according to a predetermined therapy protocol is characterized by a stored flush mode routine executable by a processor after an end-of-therapy stoppage of a pumping mechanism, whereby the pumping mechanism is operated to deliver residual liquid remaining in downstream tubing of an administration set to the patient to prevent the residual liquid from being wasted or manually administered at an unsafe rate.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.