The present invention discloses a path-type liquid medicine delivery electro-osmosis pump that can be applied to a wearable medicine device. An electro osmosis pump according to the present invention includes: a connector provided with a liquid medicine inlet and a liquid medicine outlet; a check valve assembly combined to one side of the connector; and a driver that is connected to the other side of the connector and moves the liquid medicine toward the liquid medicine outlet by applying pressure to the liquid medicine while being separated from the liquid medicine, which passes through the check valve assembly.

A device for delivering pressurized fluid includes a handle having a lumen configured to receive a container of pressurized fluid, a cap to close the lumen and an indicator to move from a first position to a second position. The first position indicates disconnection of the container from a fluid path, and the second position indicates connection of the container to the fluid path.

The present invention provides devices and methods for controlled and continuous delivery of drugs into the brain by bypassing the blood brain barrier, without the need for any surgical manipulation of the brain. The respiratory mucosa in the maxillary sinus or in the nasal region is surgically accessed from the oral or maxillofacial region through a window made on the bone overlying the mucosa. The device is used to deliver drugs in a continuous and controlled manner either beneath or above the respiratory mucosa depending on the clinical requirements, drug formulation and the volume of drug used. The drug distributes into the brain from the delivery site by bypassing the blood brain barrier without causing any significant increase of the drug in the peripheral circulation. The device can be used for continuous and controlled drug delivery into the brain by bypassing the blood brain barrier for a number of medical conditions.

Delivery pumps for providing a bolus or blenderized diet to enterally fed mammals are provided. A delivery pump according to the present disclosure is manually operated, and does not require mechanically powered operation. A delivery pump according to the present disclosure also has a size sufficient to contain an entire bolus or blenderized diet feeding, and is shaped to allow filling of the reservoir with a bolus or blenderized diet by a user. The present disclosure also includes a method of providing a bolus or blenderized diet to a mammal.

A composition includes a salt; a polymer; and an antioxidant. A dispenser includes a flexible container having a closed end and an opposed open end; an osmotically-effective solute composition encapsulating at least a portion of the container, the solute composition including antioxidant in an amount of at least 0.5 wt %, based on weight of the solute composition; a semipermeable membrane encapsulating the osmotically-effective solute composition; a cap having a sealing surface adapted for sealing engagement with the open end of the container; and a port extending from an interior of the container and through the cap. Also disclosed are methods of making and using the composition and osmotic pumps.

A substance delivery device is disclosed. The substance delivery device includes a lever that includes a drive arm that is rotatable about a pivot. The substance delivery device also includes a pump that has a deformable chamber. The deformable chamber is configured to rotate the drive arm about the pivot towards a container so as to deform the container to drive a fluid substance from the container.

Embodiments of the invention include a medicament device configured to provide stepwise instructions for using the device to a user in a particular sequence is provided. The device includes a device housing configured to receive a container, the housing including a control interface, the control interface including at least one responsive member reactive to a user input, an actuation mechanism configured to interact with the container, a signal output component associated with the device housing, and circuitry associated with the device housing configured to control a provision of the stepwise instructions to the user in the particular sequence. The container includes a first housing for containing a medicament, a second housing, and an injection member, wherein the first and second housings are movable relative to one another. The container further includes an injection member which is retractable within the second housing to prevent an unintentional contact with the injection member.

The present invention relates to a container adapted to dispense its content under pressure. The container of the present invention consists of two separate compartments separated from one another by a slidable piston. The container of the present invention contains a haemostatic paste.

The invention features a drug delivery device held in the mouth and continuously administering either a fluid comprising drug dissolved and/or dispersed in water or in a non-toxic liquid, or a drug in solid form.

The present invention is directed to treatment methods for a disease or condition, in a subject in need of such treatment, that provide alternatives to treatment by injection that give, relative to treatment by injection, improved treatment outcomes, 100% treatment compliance, reduced side effects, and rapid establishment and/or termination of substantial steady-state drug delivery. The method typically includes providing continuous delivery of a drug from an implanted osmotic delivery device, wherein substantial steady-state delivery of the drug at therapeutic concentrations is typically achieved within about 7 days or less after implantation of the osmotic delivery device in the subject and the substantial steady-state delivery of the drug from the osmotic delivery device is continuous over a period of at least about 3 months. In one embodiment, the present invention is directed to treatment of type 2 diabetes mellitus using incretin mimetics.