A drip chamber insert may include an elongate body portion comprising an upper surface, and a base portion positioned downstream of the elongate body portion for coupling to a drip chamber. The base portion may have an upper surface and a lower surface defining an outlet orifice of the drip chamber insert. The drip chamber insert may further include a first chamber and a second chamber. The first chamber may be disposed in the elongate body portion and fluidly coupled to the upper surface via an inlet orifice and to the outlet orifice via the base portion. An anti-run-dry membrane may be disposed on the upper surface of the elongate body portion extending over the inlet orifice. The second chamber may be disposed in the elongate body portion extending from the upper surface to the base portion. A low flowrate orifice may extend from a base of the second chamber into the base portion for fluidly coupling the second chamber with the outlet orifice.

A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes in a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

A roller clamp assembly for adjusting the fluid flow rate in a connector tube of an infusion set is provided. The roller clamp assembly includes a housing to receive the connector tube, a plate slideably engaged with the housing and configured to rapidly compress the connector tube to provide a coarse fluid flow adjustment, and a roller wheel moveable engaged with the housing and configured to provide a gradual fluid flow adjustment. The plate may be a slide plate received by grooves in an exterior wall of the housing and that moves orthogonally to the connector tube, or the plate may be a shim plate that moves along an interior wall of the housing in parallel to the connector tube. Infusion sets and methods of adjusting fluid flow rates are also provided.

Disclosed herein a real time multipurpose infusion monitoring and controlling unit comprising power source, monitor, micro controller and drop rate sensors, wherein said unit is performing employing horizontal screw mechanism adapted to monitor and control the drip by locking the airdrop in the saline tube to make the drip mechanism more accurately and efficiently.

The infusion pump for stem cells includes a liquor storage device and an infusion pipe. The inner wall of the liquor storage sac of the liquor storage device and inner walls of the infusion pipe are provided with an anionic protective film to prevent stem cells from adhering to the infusion pump by mutual repulsion between anions. The infusion method includes checking an infusion pump for integrity, losing a liquor stop clamp, injecting a mixed liquor of stem cells and medicine, covering a protective cap, opening the liquor stop clamp, closing the liquor stop clamp for use, connecting an external cone joint with a venous cannula, and then opening the liquor stop clamp. The method also includes steadily placing the liquor storage sac on a horizontal plane using an auxiliary placing device, and after infusion ends, closing the liquor stop clamp, and disconnecting the external cone joint.

The present disclosure is generally directed to a delivery device housed within an outer cartridge and useful for delivering a fluid to the IO space of a subject at a relatively constant volumetric flow rate over an extended period of time. The delivery device may be fluidly coupled to an existing IO access device or IV line positioned in the IO space of the subject or may be coupled to an IO access device disposed within the outer cartridge.

Modular intravenous (IV) assemblies are provided. The modular IV assembly includes a drip chamber having a body and an inlet connector, a base housing coupled directly to a base portion of the drip chamber, the base housing having an inlet port in fluid connection with the drip chamber and a flow path cavity in fluid connection with the inlet port and a flow control assembly coupled directly to a first portion of the base housing. Any of a filter assembly, an anti-run dry member, a check valve and an air vent assembly may be included in the modular IV assembly. IV sets and methods of use are also provided.

Tissue access devices and methods of using the same are disclosed. The devices can have a sensor configured to occlude a flow path by deflecting a membrane into the flow path when the devices become dislodged from tissue. The sensor can be configured to partially or fully occlude the flow path. The sensor can have a spring. The spring can be biased to move the sensor from a sensor first configuration to a sensor second configuration when a force applied by the sensor first surface against a non-sensor surface changes from a first force to a second force less than the first force. The membrane can be deflected into the flow path when the sensor is in the sensor second configuration.

A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, a needle insertion mechanism, a fluid flow connection, and a valve in fluid communication with the fluid flow connection and the needle insertion mechanism. The container has an inner volume to contain a medicament which is urged out of the container by the activation mechanism. The needle insertion mechanism is adapted to insert a needle and/or a cannula to deliver the medicament from the container via the fluid flow connection. The valve is in fluid communication with the fluid flow connection and needle insertion mechanism, and is movable between first and second positions. Upon insertion of the needle and/or the cannula, the valve remains in the first position whereby fluid flow is restricted. At a later time, the valve is urged to the second position whereby fluid may flow through the needle or cannula.

A clamp is provided. The clamp includes a flexible uniform body. The flexible uniform body includes an aperture configured to allow a tubing to pass through the flexible uniform body. The aperture is configured to allow unrestricted flow of a fluid within the tubing when the tubing is at a first position of the aperture and restrict the flow of the fluid within the tubing when the tubing is at a second position of the aperture. The flexible uniform body includes an engageable coupling mechanism disposed at a first portion of the flexible uniform body. The coupling mechanism is configured to, when engaged, cover at least a portion of the release point of the aperture such that the tubing is locked in place within the pinch point of the aperture.