An automatic injection device including a generally cylindrical syringe body having an opening, an outlet and an inner cylindrical surface adapted to contain an injectable liquid to be injected at an injection site via the outlet; a piston disposed in the cylindrical syringe body; a driving assembly, including an elongate plunger element having a forward end adapted to be axially inserted into the generally cylindrical syringe body and an at least partial forward sealing element mounted onto the elongate plunger element adjacent the forward end for creating an at least temporary slidable seal between the elongate plunger element and the inner cylindrical surface, whereby axial insertion of the elongate plunger element and the forward sealing element into the generally cylindrical syringe body creates friction between the forward sealing element and the inner cylindrical surface and also creates an at least temporary air spring between the forward sealing element and the piston, wherein the friction and the air spring dampen motion of the elongate plunger element.

A cartridge comprising a generally cylindrical cartridge main body with a proximal edge portion having a circumferential inner surface and a proximal opening surrounded by a circumferential edge, a piston slidable received therein, and a ring-formed code member attached to the circumferential edge portion and comprising an axially extending mounting portion in engagement with the edge portion circumferential inner surface, a flange portion having a distally facing mounting surface in engagement with the circumferential edge and a proximally facing stop surface, and a drive opening allowing a piston rod to engage the piston proximal surface, wherein the flange portion radially extends within the circumferential boundaries of the cartridge main body.

Described herein does a sterile protective cover comprise an intracameral therapeutic agent delivery device in the form of a pen-injector comprising a cartridge container for dispensing multiple doses of a medicament, coupled to an actuation assembly within a housing. A needle assembly is coupled to the distal end of the cartridge container, provided with a removable cap received within the housing will be in optional pre-sterile or no-sterile condition. Use of such device for the prevention or treatment of ocular conditions or diseases is also disclosed. A sterile protective cover comprising ophthalmic device, wherein the sterile protective cover is made of plastic, polythene, polyethylene, resin, rubber, polystyrene, polypropylene, polycarbonate, nylon, or combination thereof. More, particularly the present invention relates to a novel ophthalmic device of reduced length and diameter in the form of a pen-injector for precise and controlled delivery of different doses of a therapeutic agent by introducing a unique Pen grip for the device. The present invention also depicts a novel ophthalmic device comprising a multimode power on-off button that would also work with a Pulse mode to deliver a fixed quantity of medicament and also double up as a speed control to control the rate of injection and might be used with dermal filler.

Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.

An automatic injection device including a reusable driving assembly having a forward injection end and an engagement element and a disposable cassette assembly including an injectable liquid to he injected at an injection site, wherein the disposable cassette assembly is removably insertable into the reusable driving assembly at the forward injection end and is removably retained within the reusable driving assembly by snap fit engagement therewith, the snap fit engagement being effected at least partially by the engagement element, which is displaced rearwardly by insertion of the disposable cassette assembly in the reusable driving assembly.

An auto injector (4) for administering injection of a medicament from a cartridge (700) containing the medicament, the auto injector comprising: a cartridge receiver (300) with a cartridge receiver compartment (302) configured to receive a cartridge assembly (600) with at least one cartridge retention member (808) when inserted through a cartridge receiver opening (302) along a longitudinal axis; and an ejector (200) configured to support the cartridge assembly (600) by being suspended to move along the longitudinal direction and being spring-loaded in the direction opposite of the receiving direction. The cartridge receiver compartment (302) has a first section (310), at a first distance from the cartridge receiver opening (301), with inwardly extending first guide members (312) that extends over first guide member angles (314) and are spaced apart to form a passage (316) at passage angles (318) between the inward first guide members (312); wherein the inward first guide members (312) form a first bore (320) accepting the cartridge assembly (600) when inserted through the cartridge receiver opening (301). The cartridge receiver compartment (302) has a second section (330) with an annular shape, at a second distance from the cartridge receiver opening (301), and with second guide members (322) with first faces (324) that are inclined about a radial axis to the longitudinal axis and angularly arranged to extend at least partly over the passage angles (318) and the first guide member angles (314).

The invention relates to an injection device which includes a handle and a guard which together enclose a movable cartridge which can contain liquid material to be injected, and further enclose a movable injector that includes a needle, the needle being attached to a housing where the housing is attached to the cartridge, the device also including a delivery mechanism whereby the needle is moved from a retracted to an extended position, and independently the volume of the chamber may be adjusted to expel the contents thereof through the needle and into a subject in need thereof. The injection device may be communicatively connected to a control unit so as to provide a dermal injection system.

An automatic injection device including a reusable driving assembly having a forward injection end and an engagement element and a disposable cassette assembly including an injectable liquid to be injected at an injection site, wherein the disposable cassette assembly is removably insertable into the reusable driving assembly at the forward injection end and is removably retained within the reusable driving assembly by snap fit engagement therewith, the snap fit engagement being effected at least partially by the engagement element, which is displaced rearwardly by insertion of the disposable cassette assembly in the reusable driving assembly.

A device for extracting a fluid from an ampoule, comprising a plunger body (2) arranged for enclosing an ampoule (3), and a syringe body (4) movable relative to the plunger body (2). The syringe body (4) comprises a piston member (6) and an outer tubular casing (8) concentrically arranged around the piston member (6). The piston member (6) comprises an insertion end (10), receivable within the plunger body (2) and arranged for insertion in the ampoule (3), an ejection end (12) attached to the outer tubular casing (8), and a lumen (14) extending between the insertion end (10) and the ejection end (12). The plunger body (2) and the syringe body (4) form an actuating arrangement of the device (1) arranged to move the piston member (6) through the ampoule (3) during operation and forcing a fluid from the ampoule (3) through the lumen (14).