A deformable cartridge for an injection device of an injectable solution has a cartridge body having a first containment chamber of a first component of the injectable solution, having a first compression-deformable wall, a second containment chamber of a second component of the injectable solution, having a second compression-deformable wall to allow the second component to be transferred from the second containment chamber to the first containment chamber, a separation device interposed between the first and the second containment chambers and having a device body. A fluidic communication duct is defined in the device body. The deformable cartridge assumes a first operating configuration in which the fluidic communication duct is not crossable by the second component and a second operating configuration in which the fluidic communication duct is crossable by the second component. A needle holder component is fixed to the cartridge body and fluidly connected to the first containment chamber which is interposed between the needle holder component and the separation device.

A device for mixing and delivering a solution includes a tubular barrel that includes a first end, a second end, and interior compartment. A first plunger is positionable at the first end of the barrel, is moveable within the interior compartment of the barrel, and includes a spike protruding into the interior compartment, the spike having an end configured for piercing a membrane. A second plunger is positionable within the barrel, is also moveable within the interior compartment of the barrel, and has a pierceable membrane. The second plunger and the second end form a first area within the barrel for housing a first solution to be mixed and the first and second plungers form a second area within the barrel for housing a second solution to be mixed. The first and second plungers are slidably arranged within the interior area of the tubular barrel such that moving the first plunger toward the second plunger causes the spike to pierce the pierceable membrane and push the second solution through the pierced membrane to mix with the first solution in the first area.

A pre-filled medical delivery assembly assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another.

A needleless injection device is provided that includes a body forming a housing, a gas generator, a tubular reservoir that contains an active ingredient, and a T-shaped elastically deformable membrane having a tubular portion. The reservoir extends axially in the housing from an upper end to a lower end and the tubular portion is configured to extend and lie axially in the reservoir under an effect of a pressure generated by the gas generator. An injection nozzle is arranged at the lower end of the reservoir. The tubular portion is funnel shaped and includes at least an upper segment that decreases along an axial elongation direction of the member and a lower segment that increases along the axial elongation direction. The axial length of the upper segment is greater than that of the lower segment.

A plungerless aspiration and/or injection device and a method of using the same are disclosed herein. The plungerless aspiration and/or injection device includes a housing; a needle portion disposed in the housing, the needle portion configured to be selectively retracted and extended by a user, the needle potion comprising a needle tip configured to be inserted into tissue of a patient for aspiration, injection, and/or implantation; and a bulb portion disposed in the housing, the bulb portion defining a fluid containing cavity that is fluidly coupled to the needle portion, and the bulb portion being elastically deformable so that the user is able to perform the aspiration, the injection, and/or the implantation on the patient by manipulating the bulb portion.

The present disclosure relates to a medicament delivery device comprising a housing, a reservoir for medicament disposed in the housing and a dispensing member. The dispensing member is moveable relative to the housing from a first position to a second position to dispense medicament from the reservoir when the reservoir contains medicament. The medicament delivery device further comprises first and second biasing members. The first biasing member is configured to urge the dispensing member from the first position to an intermediate position. The second biasing member is configured to urge the dispensing member from the intermediate position to the second position.

A device, a method, and a system for non-intrusive percutaneous delivery of analgesia into gingiva is disclosed. The disclosure includes a frame supporting a pressable reservoir filled with liquid anesthetic and has a plurality of hollow needles terminating at or adjacent a base portion. The method may have one or more two modes. This dual modality includes a first mode, wherein a topical anesthetic disposed along or adjacent the base portion may be applied to the gingiva. During a second mode, the pressable reservoir is manually compressed, whereby the needles are urged toward the patient, entering the gingiva and delivering the anesthetic. These two modes provide for an anesthetic process at the beginning of dental procedures in preparation for the final larger dose using a hypodermic needle.

A pre-filled medical delivery system can have a blow-fill-seal (BFS) module and a mixing assembly. The BFS module can have first and second chambers, first and second sealed ports, and first and second actuation members. Each chamber can have a respective liquid agent therein. Each sealed port and each actuation member can be in fluid communication with a respective one of the chambers. The mixing assembly can be constructed for coupling to the BFS module. When coupled to the BFS module, the mixing assembly can breach the seals of the first and second ports and provide fluid communication therebetween. The disclosed systems, when assembled, can combine the liquid agents from the first and second chambers of the BFS component and deliver the combination as a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) to a patient.

This invention is a syringe having a tubular sleeve protector. The syringe has a barrel with an injection needle and a guide pin on an exterior surface of the barrel. The barrel and the injection needle are in an interior of a tubular sleeve has a spiral guide track on an interior wall. The guide pin fits in the spiral guide track and moves the barrel towards a bottom end of the tubular sleeve as the barrel is rotated, thereby extending the injection needle out of the tubular sleeve. A lateral guide track connects the spiral guide track to a vertical guide track. The guide pin moves from the bottom of the spiral guide track through the lateral guide track to the vertical guide track when the syringe barrel is further rotated. The injection needle is retracted into the interior of the tubular sleeve when the guide pin is moved into the vertical guide track and moved upwards in the vertical guide track towards a top end of the tubular sleeve.

A syringe for injecting an injectable solution contained in a deformable cartridge includes a main body provided with a receiving compartment for receiving the deformable cartridge, the main body extending between a first end portion, a first opening being defined/formed in the first end portion, and an opposed second end portion, a second opening being defined/formed in the second end portion, a crushing device having a plunger sliding with respect to the main body between a retracted position and an advanced position and bearing a crushing head sliding with respect to the main body inside the receiving compartment for deforming and crushing the deformable cartridge, a support and fixing element to which the plunger is slidably constrained, and coupling means for removably coupling the support and fixing element to the main body and/or enabling the support and fixing element to be coupled to the main body so as to change a mutual position between the support and fixing element and the main body.