A dispensing device for use with a beneficial agent has a dispensing package, a dispenser disposed on an end portion of the dispensing package, and an actuator movably disposed along at least a portion of the package between a pre-dispensing state and a dispensing state. One arrangement also provides a beneficial agent dispenser having a dispensing port, an elongate portion and a plunger that is movably disposed relative to a tubular wall of the elongate portion during a dispensing stroke to partially penetrate a separable barrier and expel the beneficial agent through the dispensing port.

The invention is a single use delivery device configured to enable reconstitution of a lyophilized agent (e.g., vaccine, drug, medicament, etc.) stored within for subsequent delivery of the reconstituted fluid agent to a patient in a controlled manner and without requiring specialized skill in reconstituting the agent or administering delivery of such agent. The delivery device is prefilled with an individual dose of a lyophilized agent and configured to be filled on-site and in the field with a dose of diluent for reconstitution of the lyophilized agent, while remaining sterile and preventing the potential for contamination during the filling process. The delivery device is further configured to be rendered incapable of reuse followings its intended use of delivering the fluid agent to a patient, thereby preventing reuse of the device and reducing the risk of the spreading blood-borne diseases through reuse.

A syringe assembly (1) having a flexible reservoir (2) containing fluid (3) at a proximal end, which is connected to a needle holding section (5) by a passageway (4) at an exit end of the reservoir. The reservoir has a seal (9) over the exit end to protect the fluid from exposure to air or contamination. The needle-holding section is threadably connected to the passageway so when the needle holding section is rotated inward toward the reservoir an inner portion of the needle (10) can pierce the seal to allow the fluid in the reservoir to pass through the needle into a user’s body when the reservoir is squeezed or depressed. A spring (12) attached to the needle holding section surrounds the length of the needle acts as a cover to help prevent accidental needle pricks.

An injection devices and methods of use are disclosed. The injection devices can be single use disposable injection devices. The injection devices can be pre-loaded with a medicament or be configured to receive a fluid delivery assembly within an aperture. The injection devices are also configurable to communicate with an electronic device and/or a central location.

An auto-injector operable to deliver a drug to a patient. The auto-injector may include a storage assembly with a first compartment and second compartment arranged to transition from an initial state in which the first compartment and the second compartment are separated to a merged state. The auto-injector may include a merging trigger configured for actuation responsive to manipulation and a merging mechanism comprising a compression element. Actuation of the merging trigger may cause movement of the merging mechanism such that the compression element compresses the first compartment.

A device for injecting a reconstitutable liquid mixture is provided. The device has a first containment chamber and a second containment chamber for a first component and a second component of the reconstitutable liquid mixture, respectively, first mechanical and fluidic connection elements between the first and second containment chambers, and second mechanical and fluidic connection elements between the second containment chamber and an injection needle. The first containment chamber has a first upper surface and a first lower surface in the shape of a cone or truncated cone having a common base and opposite extensions forming a non-zero angle β therebetween. The second containment chamber has a second upper surface and a second lower surface in the shape of a cone or truncated cone and having a common base and opposite extensions forming a non-zero angle α therebetween. The first and the second lower surfaces are deformable by compression.

A pre-filled medical delivery assembly can have first and second blow-fill-seal (BFS) modules and first and second connectors. Each BFS module can have a reservoir with a fluid agent and a neck with a seal. Each connector can have a respective recess with a piercing element. The first connector can have an outlet port, and the second connector can have an inlet/outlet (I/O) port. The connectors can be coupled together via the outlet and I/O ports. The neck of each BFS module can be inserted into the recess of the respective connector such that the piercing element breaches the seal, thereby providing a fluid path between the reservoirs. The disclosed assemblies can allow the combination of separate fluid agents via the coupled connectors and subsequently delivery of the combination as a single dose of a therapeutic agent to a patient by replacing the first connector with an administration hub.

The invention provides for a delivery system including a delivery assembly configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient.

A reservoir for a liquid medicament is described. The reservoir includes a first boundary portion and a second boundary portion forming a cavity to receive the medicament. The first boundary portion is substantially opaque and flexible. The second boundary portion is substantially transparent and rigid.

A medicant injection device includes a compressible body, a tip, and an outer luer body. The compressible body has a proximal end, a distal end, and a plurality of bellows, and defines an inner cavity for holding a liquid medicant. The tip is positioned at the proximal end of the compressible body. The outer luer body includes internal threads, and is positioned over and engaged with the tip to form a first fitting therewith. The first fitting is configured to be connected with a second fitting. A medicant injection device includes a compressible body having first and second arms, a receptacle interconnected with the compressible body and defining an inner cavity, and a first fitting configured to engage a second fitting. The compressible body is configured to be compressed by forcing the distal end of the first and second arm toward each other.