An integrated structure of a preparation syringe includes a stretchable piston, a barrel, a needle, an exposed rubber plug, a sealing sheet, a built-in rubber plug, a sealing rubber plug and an engaging rubber plug. One end of the barrel is provided with the stretchable piston, and another end of the barrel is provided with a clamping column. The exposed rubber plug is provided on a side of the stretchable piston away from the barrel. The built-in rubber plug is provided within the barrel. A Scale mark is provided on a circumferential surface of the barrel. The sealing rubber plug is inlaid and sleeved on the clamping column. The sealing sheet is provided on a side of exposed tuber plug away from the barrel. A blunt end is provided at an end of the needle away form a needle tip. The engaging rubber plug is provided outside the blunt end.

A fluid delivery device includes a housing having a bottom surface configured to be coupled to the skin surface. The fluid delivery device includes a cartridge prefilled with a fluid and configured to be inserted into the housing. The cartridge has a septum configured to be generally perpendicular to the bottom surface when the cartridge is inserted in the housing. The fluid delivery device includes a needle assembly that has a needle that includes a fluid coupling end and a delivery end. The fluid coupling end of the needle is fluidly disengaged from the cartridge in an initial position. The delivery end of the needle extends past the plane of the bottom surface and the fluid coupling end of the needle extends through the septum in a deployed position.

A discharger includes a dispensing element and a housing. The housing has a static piston connected to the dispensing element at least in a fluid conducting manner. The static piston has a piercing tip and is arranged within the housing.

A delivery system for delivering medical or pharmaceutical compounds includes a container, a closure element, an attachment element and a penetration element. The container contains the compounds and has a closed container bottom and an open second end. The closure element makes fluid-tight contact with the inner wall of the container. The penetration element has a hollow needle and moves along the longitudinal axis of the container. The penetration element includes a first link motion portion, and the attachment element includes a second link motion portion. One of the link motion portions is a projection, and the other is a guiding groove. As the projection moves in the guiding groove, the hollow needle of the penetration element moves towards the container bottom and penetrates the closure element. The penetration element moves inside the attachment element towards the container bottom based on how the projection travels in the guiding groove.

A self-admixing disposable hypodermic needle (admixing needle) includes a reservoir containing an additive, such as a buffering agent, to facilitate homogeneous mixing of the additive with an injection fluid, such as Lidocaine, contained in a cartridge held within a mechanically conjoined syringe. The admixing needle establishes a fluid communication pathway for hypodermically delivering the injection mixture to a patient preceding a potentially painful dental or medical procedure. Prior to removal, a delivery needle cap is pushed toward the syringe to dispense the additive into the cartridge. The delivery needle is then placed within the patient's tissues and the syringe is operated to force the injection mixture from the cartridge. Mixing surfaces on the male body (reservoir plunger) and the female body (reservoir) and other mechanical features homogeneously combine the injection fluid with the additive as the injection mixture travels through the admixing needle during the hypodermic injection.

Vial dosing systems and methods are disclosed. A vial dosing device includes a connecting body coupleable to a vial, a cannulated plunger having a proximal end coupled to the connecting body, a dose chamber adapted to slidably receive a distal end of the cannulated plunger and to expel medicament through a distal end of the dose chamber, and a plunger tip check valve coupled to the cannulated plunger and adapted for fluid flow from the cannulated plunger through the plunger tip check valve into the dose chamber.

The disclosure relates to a drug delivery device, comprising: an outer needle sleeve; a cartridge containing a dosage of a medicament and sealed with a sealing element that is arranged across an open distal end of the cartridge; a cartridge carrier adapted to hold the cartridge; a needle hub adapted to hold a double ended hollow needle; an inner needle sleeve arranged between the needle hub and the cartridge carrier; a removable cap coupled to the inner needle sleeve and adapted to cover and seal the needle; and a first locking mechanism adapted to lock the inner needle sleeve against axial movement in the proximal direction with respect to the cartridge carrier in an initial state, wherein in the initial state, the needle is spaced from the cartridge in the distal direction, and wherein the first locking mechanism is releasable by a rotational movement of the cap with respect to the outer needle sleeve.

A portable auto-injector configured to store a liquid component in a first chamber separately from a dry medication in a second chamber, wherein a first actuation mechanism opens a valve allowing for the initiation of a mixing step prior to injection. An extendable needle guard is provided over the delivery assembly which prevents premature injection as well as inadvertent sticks or other cross contamination of a needle. The needle guard can also form part of a secondary trigger mechanism which injects the mixed components after the mixing stage is complete.

An autoinjector is described that includes an outer body, a first trigger, an output needle, and a first compartment. The first compartment is positioned within the outer body and includes (i) a main body, (ii) a first biasing member coupled to the first trigger, and (iii) a protrusion positioned at a distal end of the main body. The autoinjector further includes a second compartment positioned in the outer body and in fluid communication with the first compartment and the output needle. The autoinjector also includes a second biasing member coupled to a second trigger. The first biasing member is configured to, upon application of force to the first trigger, automatically move an ampule in a distal direction relative to the main body to force the ampule against the protrusion, so as to break the ampule and allow a medicament to flow from the ampule to the second compartment.

The present disclosure relates to a needle arrangement for a drug delivery device. The needle arrangement includes a distal needle tip and a proximal needle tip. The distal needle tip is held in a distal needle holder and wherein the proximal needle tip is held in a proximal needle holder. The distal needle tip and the proximal needle tip are in fluid communication with each other through a fluid channel. The fluid channel is adapted to allow axial movement of the distal needle tip and relative to the proximal needle tip between a compact state and an extended state. A length of the needle arrangement over the distal needle tip and the proximal needle tip in the extended state is greater than in the compact state.