A discharger for discharging a predetermined amount of fluid from a separate container including a discharge section defining a longitudinal axis and having a proximal end and a distal end and having a discharge passage for the fluid extending between an inlet opening and an outlet opening of the discharge section. The discharger further includes an intermediate section including a distal portion cooperating with the proximal end of the discharge section and a proximal portion defining a receiving space which is adapted to be loaded with the separate container holding an amount of fluid to be discharged by the discharger. The distal portion and the proximal portion are formed in one piece and are interconnected by a breakable section.

An injector may include a container having a wall with an interior surface defining a closed sterile reservoir filled with a medical fluid or drug product. The injector may also include a fluid delivery system comprising a sterile container needle that is in fluid communication with the container in a delivery state, but may or may not be in fluid communication with the container in a storage state. The sterile container needle is attached to a connector, the connector mechanically coupled to the container to secure the sterile container needle to the container with the needle in the storage state. Further, the injector may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

Injection device comprising an elongated body (1) with a hollow needle (8) at a distal end; a reservoir for an injection material to be delivered through the needle; a plunger (3) with a first force element (5) configured to provide an injection force to said injection material, and a distal element (10) attached to the distal end of the device thereby sealing a needle lumen, wherein the distal element comprises a tissue interface and a distal seal (11), and wherein the distal seal is penetrable by a distal tip of the needle by the application of pressure on a tissue surface with the distal end of the device, wherein the penetrated distal element becomes slidable on the needle to allow advancement of the needle into tissue, wherein the penetrated distal seal opens a path for flow or delivery of the injection material from the distal end of the needle.

A medicament delivery device comprising a cannula for delivery of medicament, a cartridge assembly comprising a cartridge having a medicament chamber and a collar adjacent a distal end opening of the chamber, a sealing element for sealing the distal end opening, and a coupling element for retaining the sealing element against a distal end of the cartridge. The device further comprises a hub assembly comprising a hub body and a sealing element release member. The device is switchable from a starting configuration in which the release member is spaced from the sealing element to an activated configuration in which the release member cooperates with the sealing element to connect the medicament chamber to the cannula. The coupling element comprises an annular clamping portion for applying a clamping force to the sealing element to seal the sealing element against the distal end of the cartridge, and a generally tubular engagement portion.

A medicament delivery device is disclosed, comprising a cartridge assembly that comprises a cartridge having a medicament chamber for containing a medicament, a sealing element for sealing a distal end of the medicament chamber and a coupling element attached to the cartridge. The device also includes a sealing element release member, a cannula for delivery of the medicament, and a removable cap. The device is switchable from a starting configuration in which the release member is spaced from the sealing element to an activated configuration in which the release member cooperates with the sealing element to connect the medicament chamber to the cannula. A proximal end of the release member is sealed in a release member chamber defined in part by, the sealing element and in part by the coupling element.

A device for administering a medicinal liquid by injection is provided. The device comprises a dose assembly comprising collapsible reservoir. The device further includes at least one actuator element onto which the user may apply a force to actuate the device, the force having a component along an axis perpendicular to a longitudinal axis; and a housing comprising a septum. The at least one actuator element is configured and arranged to act on at least a portion of a dose assembly and the at least one actuator element and dose assembly are configured and arranged such that the needle is displaceable along the longitudinal axis and/or in an axis parallel to the longitudinal axis in response to an actuation force so that a portion of the needle moves from an interior to an exterior of the housing and device to allow for dispensation of the medicinal liquid.

The present invention relates to an injection device that includes a housing having an axis, and a needle sleeve that is axially movably within the housing. Axial movement of the needle sleeve into the housing is configured to actuate an injection process. The needle sleeve includes a first part that is slidably mounted to the housing, and a second part that protrudes from the housing and is rotationally coupled to the first part. The needle sleeve includes a locking mechanism that is configured to prevent axial movement of the needle sleeve into the housing until the second part of the needle sleeve has been rotated relative to the first part of the needle sleeve.

A discharger for discharging a predetermined amount of fluid includes a housing defining a longitudinal first axis and having a proximal end and a distal end, a discharge section having a discharge passage for the fluid extending between an inlet opening and an outlet opening of the discharge section, a carriage cooperating with the proximal end region of the housing such that the carriage is moveable relative to the housing along the first axis, the carriage including a receiving space for the fluid, and a piercing tip having a flow channel for establishing a flow connection for the fluid from the receiving space to the inlet opening of the discharge section, the piercing tip defining a centrally extending longitudinal second axis and having a shell surface. The shell surface of the piercing tip has an essentially convexly curved.

The present invention relates to an injection device that includes a housing having an axis, and a needle sleeve that is axially movably within the housing. Axial movement of the needle sleeve into the housing is configured to actuate an injection process. The needle sleeve includes a first part that is slidably mounted to the housing, and a second part that protrudes from the housing and is rotationally coupled to the first part. The needle sleeve includes a locking mechanism that is configured to prevent axial movement of the needle sleeve into the housing until the second part of the needle sleeve has been rotated relative to the first part of the needle sleeve.

Systems for piercing a septum of a drug delivery device is disclosed. The drug delivery device may include a needle conduit having an end and a drug container having a septum. The septum piercing mechanism may include a needle support operatively coupled to the needle conduit. The septum piercing mechanism may be movable from a first, unactivated configuration to a second, activated configuration. In the unactivated configuration, the septum seals an interior of the drug container from the end of the needle conduit. In the activated configuration, the end of the needle conduit pierces through the septum placing the needle conduit in fluid communication with the drug container. In one embodiment, activation may cause the needle support to move towards the drug container. In one embodiment, the needle support may be moved by a biasing member. Alternatively, in another embodiment, the needle support may be moved by a cam mechanism.