Devices and methods for sterilizing the outer and inner surfaces of a working end-site of a medical device such as a catheter hub, luer connector, luer component, needleless access site, and/or access port are discussed. The sterilizing device can include a housing, a sterilizing element including an antipathogenic agent configured for sterilizing the working end-site of a medical device, and a cap hingedly coupled to the housing and configured to hermetically seal the sterilizing element within the housing. One or more features on the cap and housing serve to hermetically seal the cap to the housing prior to use.

A syringe includes a barrel, a plunger, and a sealing member creating a seal between the plunger and the barrel. The barrel includes a first portion with a first inner diameter and a second portion with a second inner diameter that is larger than the first inner diameter. The sealing member engages the first portion of the barrel to give rise to a first contact pressure when the barrel is filled with product. The first contact pressure is sufficient to maintain a gas-tight seal over the expected temperature ranges 25 C. to 40 C. A first force is applied to the plunger to overcome the first contact pressure and move the plunger out of the first portion and into the second portion to dispense product. The sealing member engages the second portion of the barrel to give rise to a second contact pressure that is lower than the first contact pressure. A second force lower than the first force is sufficient to overcome the second contact pressure and move the plunger in the second portion to continue dispensing product. The syringe may include a restraining element for accommodating expansion of the product during freezing.

One embodiment of a multifunction aspiration biopsy device includes a hub having a chamber for receiving a collected specimen, a vacuum source in communication with the hub chamber, a needle detachable from the hub and having an outlet in communication with the hub chamber, and a cover extending over a portion of the needle outlet for directing a specimen collected through the needle into the hub chamber in a direction that differs from a longitudinal axis of the needle. The hub chamber with collected specimen may be separated from the vacuum source and the needle and the specimen may be triaged within the hub chamber. Various embodiments of a collection container for receiving used needles are also disclosed.

A connector mountable to a syringe barrel has a proximal barrel-engaging portion, a distal luer fitment portion, and a fluid aperture therethrough. The barrel-engaging portion of the connector includes an axial ledge configured to abut the axial distal edge of a glass syringe barrel. The connector facilitates mounting a luer assembly to the barrel. The luer assembly may be a tip cap having a complementary luer fitment for connection to the luer fitment portion of the connector. The luer assembly may be a luer needle assembly having a complementary luer fitment for connection to the luer fitment portion of the connector. The connector and syringe may further include an immobile, compressible needle seal. The needle seal is adjacent to or engageable with the barrel-engaging portion of the connector. The syringe may be configured with a plunger capable of engaging a retractable needle.

A syringe barrel includes an barrel main body having a cylinder tip at a distal end of the barrel main body; and a cap detachably attached to the cylinder tip by threaded engagement to seal an opening of the cylinder tip. The cylinder tip comprises at least one projection that projects radially from an outer periphery of a proximal end part of the cylinder tip. The cap includes a cylindrical cover that covers an outer periphery of the cylinder tip. A proximal-side inner periphery of the cover comprises a reduced radius portion, and, when the cap is threadedly engaged with the cylinder tip, a distance from a rotation axis of the cap to the reduced radius portion is smaller than a distance from the rotation axis to an outer end of the at least one projection.

Devices and methods for sterilizing the outer and inner surfaces of a working end-site of a medical device such as a catheter hub, luer connector, luer component, needleless access site, and/or access port are discussed. The sterilizing device can include a housing, a sterilizing element including an antipathogenic agent configured for sterilizing the working end-site of a medical device, and a cap hingedly coupled to the housing and configured to hermetically seal the sterilizing element within the housing. One or more features on the cap and housing serve to hermetically seal the cap to the housing prior to use.

Described herein are syringe devices, systems and methods. In general, the syringe may include a first chamber and a cartridge movable within the first chamber. The cartridge may include a cartridge chamber and a valve in fluid communication with the cartridge chamber and the first chamber and having an open configuration and a closed configuration. The valve may allow movement of a liquid out of the cartridge chamber while in a open configuration. The cartridge may also include a second end, movable within the cartridge chamber, and a locking mechanism having a locked configuration and an unlocked configuration, the locking mechanism preventing movement of the second end within the cartridge chamber while in the locked configuration.

According to the present invention, a syringe for cryopreservation of cells, a nucleic acid, or a protein comprising: a barrel having a spout and an opening and for containing cells, a nucleic acid, or a protein; a gasket slidably accommodated in the barrel; a plunger connected to the gasket; and a cap that seals the spout of the barrel, wherein the barrel is formed from a fluororesin, and the gasket is formed from a fluororesin or a polyethylene resin. The syringe is excellent in usability, durability, and safety.

The invention relates to a cap for a medical hollow body, with an engaging element which is configured such that it engages at least partially in a distal opening of the hollow medical body when the cap is arranged on the hollow medical body in the closing position, wherein the engaging element has at least one first groove, wherein a groove direction associated with the at least one first groove is aligned along an axial direction of the medical hollow body when the cap is arranged on the medical hollow body in the closing position.

A fluid path connector assembly for a medical fluid delivery system includes a connector element having a body, a lumen extending through the body, and a pair of flexible legs connected to the body, each of the flexible legs having a flange. The connector assembly further includes a dust cap removably connected to the connector element. The dust cap includes a dust cap body positioned between the flexible legs to enclose the lumen, and an engagement element at a distal end of the dust cap body. The engagement element is in contact with the flanges of the flexible legs to prevent disengagement of the dust cap from the connector element while allowing ready removal of the dust cap by medical personnel. A removable/disconnectable tamper resistant and/or tamper-evident and/or tamper resistant feature connecting the dust cap to the connector element is also disclosed.