A drug injection device includes a housing with a cartridge having a predetermined drug volume, a dose setting mechanism for setting a drug dose, and a dose delivery mechanism. A dose setting service element rotates about a longitudinal axis during the drug dose setting. The dose setting mechanism has a last dose setting device to prevent setting of a drug dose greater than the drug volume remaining in the cartridge. The last dose setting device includes a pinion coaxial with the longitudinal axis that rotates about the longitudinal axis with the dose setting service element during drug dose setting, and a rack engaged with the pinion that moves parallel to the longitudinal axis when the pinion rotates. The pinion and the rack have mutual abutment elements that prevent further rotation of the pinion after the rack has travelled an axial length correlated to the predetermined drug volume.

A medicament delivery device system for delivery of a medicament from a cartridge (10). The system comprises a first container (11) for storage of a first substance, a second container (12) received in the first container (11) for storage of a second substance, and valve means (68) for closing a distal end of the second container (12). The system further comprises a disposable cassette (102) and a reusable firing unit (200). The cassette (102) has a body (104) for receiving the cartridge (10), and a mixing element (148) for displacing the second substance into the first chamber (16) in a mixing stroke, to mix with the first substance to form the medicament. The firing unit (200) comprises a drive element (208) for expelling the medicament from the first chamber (16) in a delivery stroke and a trigger arrangement (240) for initiating the delivery stroke.

The invention discloses a sterile syringe (100) comprising a barrel (1) having internal surfaces (2), a plunger (3) movable within the barrel, a non-sliding seal (7) between the barrel and the plunger defining a sealed volume (8) and at least one filter (9) allowing only filtered gases to enter the sealed volume such that the syringe maintains its sterility even after several uses. The filters could be positioned on different locations on the syringe like on the non-sliding seal, the barrel, the barrel flange or the plunger handle.

A drug delivery device includes a container for storing a drug having a longitudinal axis. A plunger rod aligned with the longitudinal axis of the container has a first end and a second end, where the second end is disposed within the container. A stopper is disposed in and movable relative to the container for expelling the drug, and a drive mechanism is operatively coupled to the first end of the plunger rod. The drive mechanism is configured to deliver a drive force to move the plunger rod along the longitudinal axis and through the container. A chamber disposed between a plunger rod and the stopper is adapted to oppose the drive force of the drive mechanism.

A fat suction and graft syringe includes a negative pressure adjustment mechanism. The negative pressure state in a barrel can be maintained during a procedure only by pulling and releasing a plunger, and only by slightly rotating the plunger. The plunger can be pushed inside the barrel without being constrained by a multi-level holding plate and a single-surface rotation clip, whereby the syringe has enhanced convenience in the use and production thereof so that many practitioners accustomed to using a normal syringe can easily use the syringe without separately learning how to manipulate the syringe.

The present disclosure relates to an assisted injection device for injecting a composition contained in a medical container. The injection device includes a body configured to receive the medical container in a fixed position relative to the body. The injection device includes a spring-loaded piston rod translationally movable inside the body along a spring axis. The injection device includes a lever pivotably mounted on the body about a first pivot axis orthogonal to the spring axis at a first distance form the spring axis. The injection device includes a selective blocking system coupled to the lever by a second pivot axis orthogonal to the spring axis. The lever is pivotable between a rest position. The selective blocking system engages the piston rod to prevent any translation movement of the piston rod and a second position wherein the selective blocking system releases the piston rod.

A device for administering a fluid is provided, with a cylinder (16, 116) which has an open dispensing end (17), a piston (36) which is displaceable between a front and rear end position in the cylinder (16, 116) and is connected to a piston rod (35) that protrudes along a first direction beyond a rear end of the cylinder (16, 116) opposite the open dispensing end (17) and is guided in a receiving block (10), a nonreturn valve (18) closing the open dispensing end (17), and a tensioning device (S) which is connected to the piston rod (35, 135) and is arranged in the receiving block (10). The tensioning device (S) has a ramp (52) which is rotatable by means of a motor (12) and has a ramp track (53) extending along a helical line, wherein the ramp track (53) ascends from a first plateau along a region of inclination (S1, S2) to a second plateau and descends from the second plateau to the first plateau via a transition flank (46). The tensioning device (S) furthermore has a roller (51) which is in contact with the ramp track (53) and is mounted rotatably in a driver (50), which is connected to that end of the piston rod (35, 135) which protrudes out of the cylinder (16, 116), and therefore, upon rotation of the ramp (52), the ramp track (53) runs below the roller (51), which thereby rotates, wherein the roller (51) has a support region (55) which rests on the region of inclination (51, S2) of the ramp track (53), and at least one laterally adjoining side region (56, 57) which has a smaller outside diameter than the support region (55) and which does not rest on the region of inclination (S1, S2) of the ramp track (53), wherein, during rotation of the ramp, both the support region (55) and the side region (56, 57) come into contact with an edge (54) of the ramp track (53), said edge connecting the second plateau to the transition flank (46).

A medicament delivery device is presented having a housing, a delivery member cover slidably arranged in the housing, a medicament container housing arranged in the housing, a forward-biased rotator structure configured to move the medicament container housing in a forward direction in the housing, wherein the delivery member cover is configured to be moved axially from an extended position relative to the housing to a retracted position, thereby causing the rotator structure to rotate from a first rotator position to a second rotator position, and a forward-biased plunger rod extending axially inside the rotator structure and having a first axial engagement position with the rotator structure when the rotator structure is in the first rotator position and the second rotator position, the rotator structure having a first rotator guide track structure configured to cooperate with an inner surface structure of the housing.

A drug delivery device is provided, including a housing, a drug storage container, a plunger, a plunger biasing member, a releaser, and a shock absorber. The housing defines a longitudinal axis and has an opening. The drug storage container includes a barrel, a stopper, and a delivery member, where the stopper is movably positioned within the barrel. The delivery member is positioned at a distal end of the barrel and has an insertion end configured to extend at least partially through the opening during a delivery state. The plunger is moveable toward the distal end of the drug storage container to engage the stopper and expel a drug from the drug storage container through the delivery member. The plunger biasing member is coupled with the plunger and configured to urge the plunger toward the distal end of the drug storage container. The releaser member has a first position wherein the releaser member prevents the plunger from moving into the delivery state and a second position wherein the releaser member does not prevent the plunger from moving into the delivery state. The shock absorber is configured to absorb an impact force and prevent unintended movement of the releaser member.

A gas sterilizable syringe includes an enclosure having walls that define a fluid chamber. A flowable material is disposed within the fluid chamber of the enclosure. A plunger is assembled with the enclosure and is moveable toward a distal end of the enclosure for dispensing the flowable material. One or more apertures are formed in at least one of the walls of the enclosure. A gas permeable barrier covers at least one of the apertures formed in at least one of the walls of the enclosure for enabling sterilization gases to pass through the at least one aperture covered by the gas permeable barrier while preventing the flowable material from passing through the at least one of aperture. The gas permeable barrier is permeable to the sterilization gases and impermeable to the flowable material disposed within the fluid chamber of the enclosure.