A sealant delivery apparatus for use in a lung access procedure to aid in preventing pneumothorax includes a sealant applicator device and an injection needle assembly. The injection needle assembly has a hub and an elongate hollow stylet. The hub is configured for removable connection to the sealant applicator device. The elongate hollow stylet is configured to facilitate fluid communication with at least one output port of the sealant applicator device to receive a multi-component sealant. The elongate hollow stylet has a proximal portion, a distal portion having a closed distal end, and a plurality of side ports proximal to the closed distal end. The plurality of side ports radially extend from a lumen and through a side wall of the elongate hollow stylet in the distal portion. The plurality of side ports are in fluid communication with the at least one output port of the sealant applicator device.

Apparatuses and methods for delivering a fluid, including a viscous fluid. These apparatuses may include a fluid reservoir, two or more piston chambers, a manifold, a delivery port, and a drive assembly and may be configured to inject either a predetermined amount of fluid or a continuous stream of fluid. These apparatuses may also be configured to switch between filling, injection and aspiration modes. These apparatuses may generally be hand-held and lightweight and may provide a significant mechanical advantage to the user.

An injection system includes an injection system body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the injection system body, forming a proximal drug chamber between the proximal and distal stopper members and a distal drug chamber between the distal stopper member and the distal end of the injection system body. The system further includes a plunger member configured to be manually manipulated to insert the proximal stopper member relative to the injection system body. Moreover, the system includes a valve forming an openable barrier between the distal needle interface and at least a portion of the distal drug chamber. The valve is configured to allow flow from the portion of the distal drug chamber to the distal needle interface with increased pressure in the distal drug chamber.

A medicament delivery device (100) for delivery of medicament from a cartridge (10) into an injection site, through a cannula (134). The cartridge has a medicament chamber (14) with an outlet (15), and a sealing element (16) for closing the outlet (15). The device has a housing (102) for receiving the cartridge (10), and a drive mechanism (200) to expel the medicament from the device upon activation of the drive mechanism (200). The device has a connection arrangement (199) comprising a hub (166) and spring means (184) for driving relative movement between the hub (166) and the cartridge (10) upon operation of an operating member (190). The operating member switches the connection arrangement (199) from an unconnected configuration to a connected configuration, in which the hub (166) cooperates with the cartridge (10) to open the outlet (15). When connected, fluid may flow between the chamber (14) and the cannula (134).

A device (200) for mixing first and second substances. The device comprises a first container (100) for storage of the first substance and a second container (150) received in the first container (100) and for storage of the second substance. An outlet (112) is disposed at the distal end of the first container (100). Valve means (180) are provided for closing a distal end of the second container (150) and a proximal end of the first container (100). A stopper means (166) closes a proximal end of the second chamber (152) and is movable with respect to the second container (150). An operating mechanism drives relative movement between the first and second containers for causing displacement of the second substance into the first chamber (102) through the valve means (180) when the outlet (112) is closed, for mixing the first and second substances in a mixing stroke of the device.

Embodiments of a syringe-based device for procuring bodily fluid samples can include a housing having a port that can be coupled to a lumen-defining device for receiving bodily fluids, an actuator mechanism retained at least partially within the housing, the actuator mechanism including a pre-sample reservoir, a plunger operably coupled with pre-sample reservoir, a plunger cap, a plunger tube, a valve, a plunger seal, an a selectively attachable collection vial for capturing a bodily fluid sample.

A female syringe of a syringe kit includes a female syringe barrel including a cylindrical portion into which a nozzle of a male syringe is insertable, a hollow cylindrical packing arranged in the cylindrical portion, and a cap detachably attached to the cylindrical portion. When the cap is detached from the cylindrical portion, the packing remains in the cylindrical portion, a distal end opening is opened, and the nozzle of the male syringe is fitted in a liquid-tight manner to an inner side of the packing.

An apparatus for collecting, diluting and dispensing a predetermined volume of a patient fluid sample, such as blood, into the collection port of a point-of-care diagnostic test. The apparatus is constructed and arranged to collect a predefined volume of fluid sample by wicking, to mix the whole blood with a dilution reagent, and to dispense a predefined volume (within predefined tolerances) of diluted fluid sample into the collection port of the POC test kit. The apparatus has an elongate body with an internal cavity and a capillary tube in fluid connection with the internal cavity. A mixing valve separates the capillary tube and the internal cavity and selectively opens and closes the fluid connection between the capillary tube and the internal cavity. A plunger reciprocates within the valve body between a retracted limit position and a distal limit position for creating negative and positive pressure within the internal cavity.

Mixing/administration systems and methods for preparing an agent for administration to an individual are disclosed. Caps may be included as part of the system, which may include compositions comprising at least one of a cleansing, antiseptic, antimicrobial, or disinfectant agent. The caps may additionally be included that may be used for hemostasis at an injection site. Packaging and/or the mixing/administration system within it may include a tracking mechanism for data tracking regarding many different aspects of the system, including aspects of manufacture and administration.

The present disclosure relates to a syringe including a container, for containing a primary fluid, and at least one secondary fluid chamber configured to contain a secondary fluid. The container comprises a proximal end and a distal end and having a distal end opening at the distal end. The syringe further comprises a stopper, movably arranged within the container; and a plunger engageable with the stopper and configured to apply a force to the stopper to move the stopper within the container towards the distal end of the container, to expel primary fluid from the container through the distal end opening. The plunger is further configured to expel secondary fluid from the at least one secondary fluid chamber towards the distal end opening, to expel at least a portion of a residual volume of primary fluid through the distal end opening. A plunger system and assembly for a syringe and methods of expelling fluid from a syringe are also disclosed.