An infusion base for attachment to a user of an infusion set comprises an adapter having a lower portion, an inner wall portion, and a gap between the lower portion and the inner wall portion. At least one of the lower portion and the inner wall portion is configured to receive an attachment.

A protective cap is presented that is releasably connected to a medicament delivery device, which medicament delivery device is provided with an activator element at a proximal end thereof, the protective cap has first positive holding elements arranged on an inner surface of the protective cap, which first holding elements are designed to interact with second holding elements, arranged on an outer surface of the activator element of the medicament delivery device.

A multi-cartridge injector includes a plunger having a main brace and a pair of stems, each of the pair of stems having a coupler, a pair of stoppers coupled to each coupler of the pair of stems, a containment unit having a pair of barrels, and a Y-shaped conduit having a pair of branches and a common shaft, and a passageway that extends through the common shaft and the pair of branches, each of the pair of branches being in communication with an interior of one of the pair of barrels.

The invention relates to a spring driven multi-use fixed dose injection device with an End-of-Content (EoC) mechanism. A housing structure contains a volume of a liquid drug which is expelled in a predefined number of substantially equally sized dose volumes. Each dose volume is expelled automatically with the assistance of a spring which is loaded with a force sufficient to expel the full number of the predefined plurality of predetermined and equally sized dose volumes. Each dose volume is prepared and released by moving a drive element a predetermined axial distance in the proximal direction away from an initial position, followed by a rotation of the drive element by the force of the spring back to the initial position during which rotation the drive element rotates the piston rod to move helically. The End-of-Content mechanism determines how many times the drive element can be moved proximally and comprises a longitudinal track structure associated with the piston rod which has a free length defined by a proximal stop associated with the piston rod which stop prevents the drive element from moving an additional predetermined axial distance in the proximal direction required to prepare a subsequent predetermined dose volume after the predefined plurality of predetermined and equally sized dose volumes have been selected.

A drug delivery device (100, 200) for delivering a fixed dose, wherein the drug delivery device comprises: a housing assembly, a drug reservoir with a piston and a drive mechanism. The drive mechanism comprises a piston rod (109, 209) for advancing the piston to expel a drug, and a drive tube (180, 280), wherein the drive mechanism is adapted to deliver the predefined fixed dose in response to activation. The drug delivery device further comprises an activation mechanism for activating the drive mechanism, in response to moving the drive tube in an axial direction. The housing assembly comprises a guide structure for guiding the drive tube during activation and delivery of a dose, wherein the guide structure comprises an axial portion (156, 256) providing a sliding surface for guiding the drive tube during activation, and for providing a rotational stop defining an end of dose, and a helical portion (157, 257) providing a sliding surface adapted for guiding the drive tube (180, 280) during dosing. The drive tube (180, 280) comprises a guide structure comprising an axial portion (182, 282) adapted for slidably engaging the axial portion of the housing assembly for activation, and a helical portion (189, 289) for slidably engaging the helical portion of the housing assembly during dosing during dosing.

A container holder assembly for a medicament delivery device is provided having a container holder and a needle assembly, where the container holder has a distal tubular body for receiving a multi-chamber container therein, the distal tubular body comprising a distal body engaging structure on an external surface configured to movably engage an actuator device of the medicament delivery device in order to releasably connect the container holder to the actuator device, and a proximal tubular part having a proximal body engaging structure connected to the needle assembly, where the needle assembly has a hub having an injection needle with a distal needle end and a proximal needle end, the distal needle end being isolated from the multi-chamber container when the multi-chamber container is received in the distal tubular body. A medicament delivery device having a container holder assembly is also provided.

Syringes, assemblies for use in a filling process, and related methods of manufacture are disclosed. A syringe may include a reservoir filled or configured to be filled with a preselected volume of a drug, including, for example, a preselected volume of 3 mL or approximately 3 mL of the drug. The syringe may further include a wall comprising a cylindrical portion. The cylindrical portion of the wall may include: (a) an inner diameter equal to or approximately equal to a standard inner diameter of a 5 mL syringe or a standard outer diameter of any other syringe volume not equal to the preselected volume or 3 mL; and/or (b) an outer diameter equal to or approximately equal to a standard outer diameter of a 5 mL syringe or a standard outer diameter of any other syringe volume not equal to the preselected volume or 3 mL.

Provided is an insertion mechanism with increased reliability and reduced components. The insertion mechanism uses a single engagement and release clip compressed within a housing of the insertion mechanism to engage a needle hub and catheter hub. A button is provided to move the catheter hub and needle hub in a distal direction until the engagement and release clip reaches a firing window in the mechanism housing. The engagement and release clip expands in the release window to release the needle hub from the catheter hub, permitting a return spring to move the insertion needle proximally while leaving the catheter inserted, and also retains the catheter hub in the deployed position.

According to the invention a safety device for a pre-filled syringe comprises a substantially cylindrical and hollow support body and a hollow needle shield slideably arranged relative to the support body. The support body comprises at least one resilient arm and the hollow needle shield or a needle shield assembly comprises at least one curved actuation ramp. The curved actuation ramp protrudes in a lateral direction (L) perpendicular to a central axis (A) of the safety device. The curved actuation ramp comprises a first lateral dimension (L1) at a proximal end of the needle shield and a second lateral dimension (L2) exceeding the first lateral dimension (L1) at a distal end of the needle shield. The resilient arm engages the curved actuation ramp when the needle shield is slid relative to the support body.

A puncture apparatus includes: a needle member having a tubular shape and comprising a flexible portion that is deformable; and a puncture assisting member that is movable or deformable in an axial direction of the needle member between: a restricting position in which the puncture assisting member is located outside the flexible portion of the needle member in a radial direction of the needle member, and thereby restricts deformation of the flexible portion, and a permissive position in which the puncture assisting member is not located outside the flexible portion in the radial direction, and thereby permits deformation of the flexible portion. The puncture assisting member is configured to move or deform from the restricting position to the permissive position in conjunction with an operation of inserting the flexible portion into a living body at a time of puncturing the living body with the needle member.