A lock adapter, a syringe assembly, and a prefilled syringe capable of suppressing variation in position on the tip end side of the lock adapter after being subjected to an autoclave sterilization process. The lock adapter is attached to the periphery of a nozzle portion at the tip end of the prefilled syringe and slidable in an axial direction of the nozzle portion. The lock adapter includes: a cylindrical body portion surrounding the periphery of the nozzle portion; and a claw portion protruding to an inner peripheral side from a base end portion of the cylindrical body portion and configured to determine a tip end position of the lock adapter by being caught in an annular rib extending in a circumferential direction of the nozzle portion, in which the claw portion has a circumferential shape when viewed from the axial direction and is integrally connected in the circumferential direction.

A medical puncture needle is configured to reliably administer a sufficient amount of a liquid medicine to thin tissue. The medical puncture needle includes: a main body having a cylindrical shape and having inside a through hole; a blade surface that has an annular shape and that is cut into a tapered shape so that a thickness of the main body reduces toward a tip part of the main body; and a blade edge that has an annular shape, the blade edge being formed at a tip of the blade surface so as to extend along a plane orthogonal to a central axis of the main body.

A medical puncture needle includes: a metal needle body formed in a tubular shape, the needle body including: a blade surface located at a distal end portion of the needle body, a planar reflection portion located at an inner surface of the needle body and configured to reflect light, and a transmission window located proximal of the blade surface and configured to transmit reflected light reflected by the planar reflection portion.

The embodiments of the present disclosure provide a pierceable stopper, comprising a plug portion, and a disk portion disposed on top of the plug portion and comprising a flange extending radially beyond an outer diameter of the plug portion. The embodiments also provide a lyophilization stopper, comprising a body comprising an integral hinge means, and a flange extending radially beyond an outer diameter of the body. Additionally, the embodiments provide a probe assembly, comprising a first needle comprising a hollow cavity and a pointed tip, and a second needle disposed inside the hollow cavity and comprising a rounded tip. The embodiments further provide a cartridge assembly, comprising a first housing comprising a first set of cavities configured to accommodate one or more containers, and a second housing comprising a second set of cavities corresponding to the first set of cavities when the second housing is coupled to the first housing.

A puncture needle includes: a rod-shaped main body; and a blade surface located at a distal end portion of the main body, which includes: first, second, and third blade surface portions. The first blade surface portion and the second blade surface portion form a blade edge at a ridge line where the first blade surface portion and the second blade surface portion meet, wherein a needle tip is located at a distal end of the blade edge. The third blade surface portion is contiguous with a proximal side of at least the first blade surface portion, and the third blade surface portion is a single flat surface that is inclined with respect to a central axis of the main body. In a side view of the main body, a line extending along the third blade surface portion intersects with the first blade surface portion.

A needle system (10) comprises a needle arrangement and an actuator device (30). The needle arrangement comprises needle (21) and a rod (24). The needle has a proximal end (211) and a distal end (212) and a needle opening (203) at the distal end of the needle. The rod has a proximal end (221) and a distal end (222) and a length that is greater than the length of the needle. The rod comprises an elongated rod shaft portion (26) configured to fit inside the needle and a rod tip portion (23) located at the distal end of the rod. The actuator device comprises an actuator body (39) comprising a cavity (33) and a first opening (61) configured to interface with a fluid transportation device (70) to allow fluid into and/or out of the cavity and thereby allowing fluid to be injected and/or aspirated through the needle. The needle system has a closed state and an open state. The rod tip portion seals, or blocks, the needle opening in the closed state, and the rod tip portion is shifted forward relative to the needle and unseals, or unblocks, the needle opening in the open state. The proximal end of the needle is connected to the actuator body and the proximal end of the needle is open to the cavity. The rod is configured to interact with the actuator device such that at a change of volume of the cavity, a force is exerted on the rod in a distal direction, setting the needle arrangement in the open state.

Devices, systems, and methods are provided herein for delivering medication (e.g., insulin) via a wearable pump having a patch-style form factor for adhesion to a user's body. The reusable pump may be coupled to a disposable cap housing a microdosing system for delivering precise, repeatable doses of medication to a cannula configured to deliver medication to a target infusion area beneath the user's outer skin layer. The system further may include an applicator for inserting the cannula into the user's skin and/or applying an adhesive pad to the skin.

A feedback-type intelligent syringe is provided, which includes a syringe needle and a needle seat, the syringe needle is provided with a first electrode and a second electrode for detecting impedance of a human tissue, the first electrode and the second electrode are electrically connected with a main control device, and the main control device is electrically connected with a displayer or a reminding device.

A needle assembly for medical or surgical use is disclosed, such as for hemodialysis. A representative needle assembly comprises an outer needle assembly and an integral needle tip protector. A representative outer needle assembly comprises: an outer needle comprising: a first lumen; a first aperture with a sharp needle tip at a first distal end of the outer needle; and a second aperture arranged opposite the first aperture. In another embodiment, the outer needle has a longitudinal slot and the integral needle tip protector includes a sliding connector which is slidable in the longitudinal slot. The integral needle tip protector is arranged within the first lumen and moveable between a retracted configuration and an extended configuration, and comprises: a needle tip cover arranged to shield the sharp needle tip in the extended configuration, the needle tip cover having a smooth or beveled distal surface forming a blunt tip.

Described here are systems and methods for accessing Schlemm's canal, for delivering a fluid composition therein, and for tearing the trabecular meshwork. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. The systems described here may be configured to cut or tear the trabecular meshwork with the body of an elongate member located within Schlemm's canal.