A needle hub (10) includes a core mounting structure (27), a first panel (28) and a second panel (29) connected to the core mounting structure (27) with an opening formed between the first panel (28) and the second panel (29), an introducer needle (72) fixedly attached to the core mounting structure (27) for insertion into a patient, and an actuation lever (16, 18) cantilevered longitudinally at a central portion thereof from the core mounting structure (27) and having an actuation button (12, 14) disposed at a proximal free end and a latch (24, 26) disposed at a distal free end.

A method of dispensing a therapeutic fluid from a line includes providing an inlet line connectable to an upstream fluid source. The inlet line is in downstream fluid communication with a pumping chamber. The pumping chamber has a pump outlet. The method also includes actuating a force application assembly so as to restrict retrograde flow of fluid through the inlet while pressurizing the pumping chamber to urge flow through the pump outlet. A corresponding system employs the method.

In an embodiment provided herein, an injection simulation device including a housing having a proximal end and a distal end is provided. The injection simulation device embodiment comprises a plunger having a proximal end, a distal end and being slidable relative to the housing, and a retractable injection simulation member at the distal end of the housing, at least one biasing member associated with the retractable injection simulation member and associated with the plunger, wherein a first force on a distal end of the injection simulation member causes movement of the injection simulation member from an extended position to a retracted position, to compress the first biasing member, and simulate the tactility of an injection to a user; and wherein a second force on the proximal end of the plunger asserts a third force on the first biasing member to facilitate resetting the injection simulation member to the extended position.

A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.

Systems and methods for automatic intravenous injection in accordance with embodiments of the invention are illustrated. One embodiment includes a method for automatically injecting a needle into a vein. The method includes steps for identifying an injection position using a first set of one or more sensors, positioning an injection mechanism at the identified injection position, and vertically inserting a needle until entry in a vein is detected using a second set of one or more sensors.

According to the invention a safety device for a pre-filled syringe comprises a substantially cylindrical and hollow support body and a hollow needle shield slideably arranged relative to the support body. The support body comprises at least one resilient arm and the hollow needle shield or a needle shield assembly comprises at least one curved actuation ramp. The curved actuation ramp protrudes in a lateral direction (L) perpendicular to a central axis (A) of the safety device. The curved actuation ramp comprises a first lateral dimension (L1) at a proximal end of the needle shield and a second lateral dimension (L2) exceeding the first lateral dimension (L1) at a distal end of the needle shield. The resilient arm engages the curved actuation ramp when the needle shield is slid relative to the support body.

A medicament delivery device is presented having a housing with an inner surface structure, a delivery member cover slidably arranged in the housing, a medicament container housing arranged in the housing, a rotator configured to cooperate with the inner surface structure, the rotator being in axial engagement with the medicament container housing, wherein the delivery member cover is configured to be moved axially from an extended position relative to the housing to a retracted position, thereby causing the rotator to rotate from a first rotator position to a second rotator position, a forward-biased plunger rod extending through the rotator and having a first axial engagement position with the rotator when the rotator is in the first rotator position and in the second rotator position, wherein the rotator has an engagement structure configured to engage with the inner surface structure when the rotator is in the first rotator position to prevent forward movement of the rotator, and wherein the rotator is configured to disengage from the inner surface structure when the rotator is rotated from the first rotator position towards the second rotator position, causing the rotator, the plunger rod and the medicament container housing to move forward an auto-penetration distance in the housing.

A puncture device guide includes a body member configured to fixedly attach to an ultrasound probe, a slide member slidingly received within the body member; and a cradle member slidingly received within the slide member and longitudinally fixed relative to the body member. The cradle member is configured to receive a puncture device therein. Longitudinal movement of the slide member causes radial movement of the cradle member relative to the body member.

An injector for delivering a therapeutic product may include a base having a flexible surface that conforms to various body contours of a patient and defines one or more an injection chambers. The injector may have a height that is substantially less than its width, thereby defining a low profile, which provides a larger more stable base that can pinch or stretch the skin in a controlled manner. The larger base can also accommodate larger volumes via multiple injection chambers and/or large combined primary containers.

A drug injection device contains a needle holder, an ejector, a needle member, and an actuation assembly. The needle holder defines a drug delivery direction extending toward the injection end. The ejector contains a fixing segment that is fixed to the needle holder and located in the drug delivery direction, and the abutting segment extending toward the injection end and protruding beyond the needle holder. The needle member is movably arranged relative to the needle holder and contains a needle shaft connected to a needle hub coaxially arranged with the ejector for the abutting segment inserting into the needle shaft. The actuator assembly connects the needle holder and the needle shaft for driving the needle member between a first position and a second position with respect to the needle holder.