There is provided an inhaler article (10) having an upstream end (1) and a downstream end (2). The inhaler article comprises an upstream section (3) which comprises an end plug (5). The inhaler article comprises a downstream section (4) located downstream of the upstream section and spaced apart from the upstream section. The downstream section comprises a filter segment (6). The resistance to draw per unit length of the filter segment is greater than 0 millimetres of water per millimetre and less than about 3 millimetres of water per millimetre. The inhaler article comprises a cavity (7) defined between the upstream and downstream sections, and configured to be in fluid communication with the exterior of the article. The inhaler article comprises a capsule (9) containing an inhalable material, and located in the cavity. There is also provided an inhaler system (100) comprising such an inhaler article and a holder (120).

A dry powder inhaler (1) for pulmonary or nasal use, employing capsules (6) containing a dose of powder for inhalation, comprising four components: a capsule tray (2), a cover (4) and a mouthpiece (8) and an inhaler body (3). Air is drawn by the patient via the mouthpiece (8) which is in communication with the capsule (6) and travels via air paths through the device (1) and through the capsule (6) thereby dispersing and entraining the dose of powder. The capsule (6) is cut by cutting means (18, 19) located on the body (3). The inhaler body (3), the mouthpiece (8) and the cover (4) are provided with hinge segments (20, 35, 42) which when assembled together and the mouthpiece (8) is locked into the body (3), form a single hinge (5) and which allows the cover (4) to freely pivot around the body (3) and the mouthpiece (8).

A holder (150) for an inhaler article (110) includes a housing (151) defining an inhaler article cavity (154). A piercing element (160) is fixed to and extends into the inhaler article cavity. A sleeve (180) is disposed within the inhaler article cavity and is configured to retain an inhaler article. The sleeve is movable along the housing longitudinal axis. A spring element (200) is configured to bias the sleeve toward the open proximal end (156) of the housing.

A vapor-generating system includes a cartridge, a vapor-generating device and a piercing element. The cartridge includes a cartridge housing configured to hold a solid vapor-forming substrate within the cartridge housing interior, a liquid storage housing configured to hold a liquid vapor-forming substrate within the liquid storage housing interior, and a frangible seal on the liquid storage housing. The vapor-generating device includes a device housing at least partially defining a cavity, an electric heater, and a power supply. The piercing element is configured to pierce the frangible seal of the cartridge to expose the liquid storage housing interior to be in fluid communication with the electric heater based on the vapor-generating device coupling with the cartridge such that the device housing at least partially receives the cartridge into the cavity. The electric heater is located externally from the piercing element.

The invention relates to a spray head for a device for dispensing a fluid product, having a body provided with a spray orifice, a central channel being connected to the spray orifice via a spray profile having a vortex chamber arranged directly upstream of the spray orifice, the spray profile having at least two curved channels extending from the central channel to the vortex chamber, each curved channel connected non-radially to the vortex chamber, to form a spray exiting the spray orifice, each curved channel having a convex shape, diverging laterally outwards from the central channel, and then from an inflection point, returning laterally inwards towards the vortex chamber.

Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose.

A device is provided for delivering one or more substances within at least one body cavity. The device includes at least one pierceable vial comprising V.sub.sub [ml or mg] of the substances; the vial having at least one fluid discharging outlet port, configured for placement in proximity to the body cavity. The pierceable vial is configured to interface in a sealable manner with at least one pressurized fluid at volume V.sub.PF [ml] and pressure P.sub.PF [barg]. The device, upon actuation, permits the pressurized fluid to enter into the pierceable vial via the at least one fluid inlet port, entrains the substances, and delivers the substances through the fluid discharging outlet port to within the body cavity in the form of at least one selected from a group consisting of drops, droplets, stream, aerosol and any combination thereof.

A drug delivery device (400) comprises a tip (416) configured to be positioned in a nose of a patient, the tip having an opening (414) therein, a coupling mechanism (402) configured to releasably couple to a first vial (404) containing a first drug therein, to release the first vial therefrom, and to subsequently be releasably coupled to a second vial containing a second drug therein, and a plunger configured to be actuated to cause the first drug to exit through the opening and to be subsequently actuated to cause the second drug to exit through the opening. The same drug delivery device is therefore configured to deliver multiple doses. There are also disclosed various exemplary reloadable drug vials for multi-dose delivery, drug products utilizing the same, and methods of using reloadable drug vials for multi-dose delivery.

Device having a reservoir, a head provided with a dispensing hole, a stopper displaceable in the reservoir between a rest position and an actuation end position to dispense fluid product through the dispensing hole. The reservoir formed by a hollow, blind body having a base and a single opening which, in the rest position, is closed in a fluid-tight manner by the stopper, the device having an insert fixed in the head, the insert supporting a cannula for piercing the stopper and connecting the reservoir to the dispensing hole. The insert has at least one projection provided with a lower surface, the lower surface cooperating at the end of actuation with the reservoir in order to define the actuation end position of the stopper.

A nebulizer for a fluid, includes a container containing the fluid; a housing part which can be detached from the nebulizer for replacing the container; an inner part; a retaining element connected with and not detachable from the inner part, where the housing part is releasable fixed to the inner part by the retaining element; a delivery mechanism for dispensing the fluid; a manually depressible actuator member, which is a separate part from the retaining element and acts on the retaining element, and wherein the actuator member is depressed to elastically deform or flex the retaining element to allow detachment of the housing part.