A stable dry powder composition for inhalation includes acetylsalicylic acid in particles having a mass median aerodynamic diameter (MMAD) in a range of about 1 μm to about 5 μm. The dry powder composition may contain a pharmaceutically acceptable excipient, such as a stearate, in an amount ranging from about 0.04% (w/w) to about 0.06% (w/w), or from about 0.4% (w/w) to about 0.6% (w/w), of the composition.

An inhaler for inhalation of a formulation in powder form includes: a magazine which is rotatable and contains pre-dosed doses of the formulation in capsules, a housing which is substantially round or disc-shaped, the housing having a housing part in which the rotatable magazine is disposed, where the housing part is fixedly coupled to the rotatable magazine, and is removable from the housing in order to facilitate replacement of the magazine by inserting a new magazine.

Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose.

A portable medical spray includes a tubular body having a room defined therein, and a breakable portion is formed to the top end of the body. A connection portion extends from the bottom end of the body. A nozzle is connected to the top end of the body. The nozzle has a passage which is located corresponding to the breakable portion. A medicine cell is located in the room of the body and has medicine received therein. The medicine cell is a compressible bellow cell. A needle is located in the medicine cell. An end part is mounted to the connection portion. The end part is pushed toward the nozzle to compress the medicine cell, and the needle penetrates through the top end of the medicine cell and the breakable portion to release the medicine via the nozzle.

A nebulizer and a storage device are provided. The nebulizer includes a casing, an atomization module fixed to the casing, a rotating module rotatably assembled to the casing, a linking module assembled to the rotating module, and a locking module. The linking module is configured to be connected to a bottom of the container bottle, and the starting module is configured to drive the nebulizer by being pushed, thereby enabling liquid in the container bottle to be atomized toward an outside of the nebulizer through the atomization module in an atomization process. The locking module is configured to be connected to a bottom of the container bottle. When the nebulizer completes a predetermined number of times of the atomization process, the locking mechanism is moved toward the casing and is then limited to restrict an operation of the nebulizer. Accordingly, after the nebulizer completes the predetermined number of times of the atomization process, the locking module can restrict rotation of the rotating module for preventing the nebulizer from using the container bottle arranged therein.

The invention provides a capsule inhaler for administering a single dose of dry powder, comprising a body and a mouthpiece, and a cover, coupled with the body. Additionally, the inhaler comprises a capsule receiving element and press buttons with a capsule piercing mechanism as well as an electronic board comprising a microprocessor, a magnetic field sensor and a light indicator, positioned close to the press button that comprises a piercing element and a magnet. Moreover, the invention provides a method for monitoring intake of a substance by means of a capsule inhaler, comprising steps of controlling intake of a substance and providing feedback to the user during intake of the substance. The invention also provides a computer program and a computer program product capable to execute steps of the method.

The present invention provides a passive inhaler for use in treating a number of diseases. The inventor has shown that the compositions comprised in the inhaler can be delivered to the lungs and to the brain in pharmacological relevant dosages, to treat a number of diseases in the lungs and the brain. Further, the inhaler is also able to deliver substances to the brain which may enhance transport across the blood brain barrier.

The present invention provides a particulate delivery device with an automatic activation mechanism that pierces or cuts a composition capsule when a cap is removed. The cap cannot be replaced once the device is activated for use. The device allows for gas flow through the device from a gas inlet to a gas outlet through a composition receptacle and dispersion chamber to deliver particulate to the airway of a subject.

An aerosol-generating system is provided, including an aerosol-generating device including a heater element, and an aerosol-generating article configured to engage with the aerosol-generating device, the aerosol-generating article including a medicament source, a volatile delivery enhancing compound source, and at least one frangible barrier sealing the medicament source and the volatile delivery enhancing compound source, the aerosol-generating system further including a rupturing portion forming part of the aerosol-generating device or the aerosol-generating article, the aerosol-generating system being configured to allow relative sliding movement between the rupturing portion and the at least one frangible barrier to rupture the at least one frangible barrier.

The invention provides a capsule inhaler for administering a single dose of dry powder from a capsule, and comprising a body and a mouthpiece with a sieve and a mouthpiece base, and a cover having an opening, coupled with the body. Additionally, the inhaler comprises a capsule receiving element and press buttons with a capsule piercing mechanism. In the body of the inhaler an electronic board is arranged with a microprocessor, said board comprising a magnetic field sensor and a light indicator, arranged in the proximity of the press button that comprises a magnet. The magnet is positioned at the piercing element, and in the proximity of the magnet a magnetic field sensor is arranged, and the electronic board of the inhaler is coupled with the mouthpiece base via a coupling element.