A tubular body that includes a plurality of first wires distributed in an annular portion of the tubular body, and a plurality of deformed second wires alternately disposed between each of the plurality of first wires, the plurality of first wires and the plurality of deformed second wires being in an alternately twisted arrangement in a longitudinal direction of the tubular body, where each of the plurality of first wires has a substantially circular shape in a cross section view, and each of the plurality of deformed second wires has a non-circular shape in the cross section view, has an arcuate side portion that receive a part of a side surface of an adjacent wire of the plurality of first wires, and has an annular sector shape protruding in a radial direction in the cross section view of the tubular body.

A medical probe includes a hollow guidewire, a balloon, and a magnetic position sensor. The hollow guidewire is configured for insertion into a channel of an organ of a patient. The balloon is fixed to a distal end of the hollow guidewire, is configured to be inserted into the channel using the hollow guidewire, and is further configured to be inflated by pumping of fluid through the hollow guidewire. The magnetic position sensor is fitted at the distal end of the hollow guidewire.

Attachment of tubes of various constructions for use in a microcatheter, including joining to a multifilar helix. Methods of uses and construction with concentric tubes axially displaceable over one another to control navigability and/or positioning properties of a microcatheter.

A guide wire configured for intravascular insertion includes a core wire having a flattened portion configured to allow the core wire to preferentially bend in at least one plane that passes through a longitudinal axis of the core wire. A distal most end of the flattened portion is spaced from a distal most end of the core wire. The guide wire may further include a sensor element configured to measure a physiological variable in a living body and a coil surrounding a portion of the core wire.

A medical probe includes a hollow guidewire, a balloon, and a magnetic position sensor. The hollow guidewire is configured for insertion into a channel of an organ of a patient. The balloon is fixed to a distal end of the hollow guidewire, is configured to be inserted into the channel using the hollow guidewire, and is further configured to be inflated by pumping of fluid through the hollow guidewire. The magnetic position sensor is fitted at the distal end of the hollow guidewire.

A guide wire that includes a core shaft that is made of a first material, a coil that is provided to cover an outer periphery of the core shaft and is formed by twisting a first wire made of the first material and a plurality of second wires made of a second material different from the first material, and a distal end joint that joints a distal end of the core shaft and a distal end of the coil, and the distal end joint is made of the first material and is continuous from the distal end of the core shaft and the distal end of the first wire, and the distal end joint wraps the distal ends of the plurality of second wires.

A medical guidewire includes a flexible spiral coil, a fiber, and a strengthening element. The coil is configured to guide a medical device into a patient body. The fiber extends along at least part of the coil, is coupled to the at least part of the coil at one or more first predefined locations and is configured to mechanically strengthen the at least part of the coil. The strengthening element is coupled to one or more second predefined locations along a distal section of the coil, and is configured to mechanically strengthen the distal section.

A tubular body that includes a plurality of first wires distributed in an annular portion of the tubular body, and a plurality of deformed second wires alternately disposed between each of the plurality of first wires, the plurality of first wires and the plurality of deformed second wires being in an alternately twisted arrangement in a longitudinal direction of the tubular body, where each of the plurality of first wires has a substantially circular shape in a cross section view, and each of the plurality of deformed second wires has a non-circular shape in the cross section view, has an arcuate side portion that receive a part of a side surface of an adjacent wire of the plurality of first wires, and has an annular sector shape protruding in a radial direction in the cross section view of the tubular body.

Provided herein is a device for advancement of an instrument into an intravenous catheter assembly. The device includes a housing having a proximal end, a distal end, and a sidewall therebetween defining an interior. A displaceable instrument is received within the housing interior and has a proximal end and a distal end, with the instrument being one of a guidewire and a probe. The instrument is advanceable from a first, proximal position in which the distal end does not extend beyond a distal end of a catheter of the intravenous catheter assembly, to a second, distal position in which the distal end extends beyond the distal end of the catheter of the intravenous catheter assembly. The distal end of the instrument includes an antithrombogenic material, the antithrombogenic material being an antithrombogenic coating applied to the instrument or an antithrombogenic composition from which the instrument is formed, in part.

An instrument advancement device includes an access connector configured to be connected to a vascular access device, a primary lumen in fluid communication with the access connector, an instrument received within the primary lumen and having a retracted position and an extended position, an advancement member configured to move the instrument between the retracted position and the extended position, and a lumen seal received within the primary lumen and connected to the instrument. The lumen seal defines a space between the lumen seal and the primary lumen when the instrument is in the retracted portion. The lumen seal engages the primary lumen when the instrument is in the advanced position.