A delivery guidewire (100), comprising: a core wire (110) comprising a first segment (111), a second segment (112) and a third segment (113), which are arranged in sequence and have diameters decreasing in the direction from a distal end to a proximal end of the delivery guidewire (100); a metal ring (130) at least partially disposed at a proximal end of the first segment (111); and a spring (120) at least partially disposed over the outer side of the second segment (112). A distal end of the spring (120) abuts against a proximal end of the metal ring (130), and a distal section of the spring (120) has a diameter smaller than a diameter of a proximal section thereof. The diameter of the distal section of the spring (120) that is smaller than the diameter of the proximal section of the spring (120) results in a smaller clearance between the distal section of the spring (120) and the core wire (110), which enables greater concentricity of the distal section of the spring (120) with the core wire (110). Also provided is a method of making a delivery guidewire (100).

A guide wire is disclosed, which is capable of reducing an unintended deviation in a guide wire position while preventing an occurrence of discomfort with respect to usability. The guide wire has a flexible core wire, and has a distal core portion, a main body portion, and a rigidity changing portion that gradually decreases in rigidity from the main body portion toward the distal core portion. The rigidity changing portion includes a first tapered portion continuous with a distal end of the main body portion, a second tapered portion continuous with a distal end of the first tapered portion, and a third tapered portion continuous with a proximal end of the distal core portion. A boundary portion between the first tapered portion and the second tapered portion is located in a range of 300 to 400 mm from a foremost distal end of the distal core portion.

Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire having a core wire formed of multiple materials. For example, a sensing guide wire is provided that includes a core member having an inner section and an outer section surrounding the inner section, wherein the inner section is formed of a first material and the outer section is formed of a second material that is different than the first material; and a sensing element coupled to a distal portion of the core member. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided.

A medical guidewire includes an electrically conductive core, a polymer tubing that encloses at least a portion of the electrically conductive core, and a trackable electromagnetic element formed in a distal end of the medical guidewire. The trackable electromagnetic element includes a coil. A first end of the coil is electrically coupled to an electrically conductive structure such as a metallic braid in the polymer tubing, and a second end of the coil is electrically coupled to the electrically conductive core.

An access needle includes a hollow shaft having a lumen sized and shaped to slidably receive a guidewire therein and having a distal end including an angled surface extending proximally and transversely from a sharpened distal-most tip of the shaft to a beveled smoothed area of the shaft proximal and transverse to the sharpened tip. The beveled smoothed area is positioned to slidably engage a guidewire extended distally out the distal end of the needle so that, as the guidewire is retracted proximally into the needle, the beveled smoothed area slidably engages the guidewire to minimize abrasion to the guidewire.

The disclosure provides a system and method for a programmable medical wire that can be preprogrammed, and controlled and reshaped upon command. The system can include a power supply, a controller, and a multilayered wire assembly. The wire assembly includes a core conductor, actuator conductors coupled to the core conductor, selective conductors formed adjacent the core conductor and the actuator conductors, and a protective biocompatible shield around the layers. The selective conductors can be energized to activate the actuator conductors and cause the actuator conductors to bend or twist in a preprogrammed manner. By selectively controlling the direction of movement of the actuator conductors, the wire assembly can be remotely guided through body passageways to the target. Auxiliary equipment such as sensors, micro cameras, detectors, cutters, and other equipment can also be coupled to the wire assembly, and controlled and communicated with through one or more of the selective conductors.

A medical guidewire system including an inner member having an outer diameter and an outer member having an inner diameter, the inner diameter being larger than the outer diameter. The inner and outer members are relatively slidable to adjust a stiffness of the guidewire system. The lumen of the outer member forms a gap for fluid flow therethrough. A connector to the inner member and a fluid infusion channel communicating with the gap for injection of fluid through the gap to exit a distal portion of the outer member.

Disclosed are intravascular devices for navigating tortuous vascular environments like the human brain. The disclosed guidewire includes a core wire, a first tube within which the distal section of the core is inserted, and a second tube within which the proximal section of the core is inserted. The first and second tubes have a substantially similar outer diameter such that the guidewire has a uniform outer diameter over its complete length for effective catheter tracking over the guidewire.

In the present disclosure, embodiments of dual-stage syringes are disclosed along with delivery systems incorporating the dual-stage syringes. Embodiments of the dual-stage syringes described herein include sleeved dual-stage syringes, turn-key dual-stage syringes and dual-stage syringes including one or more one-way valves.

The present disclosure relates to guidewire devices with an outer tube and a core. The distal section of the core extends into and is surrounded by the outer tube. One or more centering mechanisms are also disposed within the outer tube and are arranged to fill a portion of the annular space between the core and the inner surface of the tube. The one or more centering mechanisms thereby assist in keeping the distal section of the core axially aligned within the tube, which enables effective control of the device and minimizes undesirable whip movements of the guidewire.