The present disclosure relates to guidewire devices having shapeable tips and effective torquability. A guidewire device includes a core having a proximal section and a tapered distal section. A tube structure is coupled to the core such that the tapered distal section of the core extends into and distally beyond the tube structure. The portion of the core extending distally beyond the tube forms a shapeable tip. One or more coils also extend distally beyond the tube. The tip is configured to reduce the tendency of resilient forces from the tube structure to disrupt a customized shape of the tip.

A medical device includes: an elongated member having a proximal end, a distal end, and a body extending between the proximal end and the distal end; wherein at least a first portion of the elongated member comprises a first segment made from a shape-memory material, and a second segment made from a non-shape-memory material, the first portion being a distal portion of the elongated member; wherein the first segment and the second segment of the distal portion of the elongated member are secured to each other along their respective longitudinal sides; and wherein the first segment is configured to undergo length change to cause the distal portion of the elongated member to bend.

A medical system includes a source of a material, a first tube, and a second tube. The material is configured to expand and form a porous body after the material is deployed into a body lumen. The first tube is configured to deliver the material into the body lumen, and the second tube is configured to apply suction to the porous body.

A method for making a neutral hybrid braided structure may involve positioning a first set of wires on a braiding machine in a first set of positions, positioning a second set of wires on the braiding machine in a second set of positions so that the first set of positions and the second set of positions form a neutral hybrid braiding pattern, and braiding the first set of wires and the second set of wires on the braiding machine to form the neutral hybrid braided structure. Each wire in the first set of wires has a first cross-sectional diameter, and each wire in the second set of wires has a second cross-sectional diameter that is smaller than the first cross-sectional diameter.

A stylet for use in guiding a distal tip of a catheter to a predetermined location within the body of a patient. In one embodiment the stylet is configured for use within a lumen of the catheter and comprises a core wire, an ECG sensor, and a magnetic assembly. The ECG sensor senses an ECG signal of a patient when the stylet is disposed within the lumen of the catheter and the catheter is disposed within the body of the patient. The magnetic assembly includes at least one element capable of producing a magnetic or electromagnetic field for detection by a sensor external to the patient. In another embodiment, the stylet includes a pre-shaped distal segment that is deflected with respect to a more proximal portion of the stylet, which in turn causes a distal segment of the catheter to be deflected when the stylet is received within the lumen.

The present disclosure relates to guidewire devices having shapeable tips and effective torquability. A guidewire device includes a core having a proximal section and a tapered distal section. A tube structure is coupled to the core such that the tapered distal section of the core extends into and distally beyond the tube structure. The portion of the core extending distally beyond the tube forms a shapeable tip. A polymer covering encompasses the tip. The tip is configured to reduce the tendency of resilient forces from the tube structure to disrupt a customized shape of the tip.

A method of treating a patient includes providing a guidewire having an elongate body defining a proximal end and a distal end, the elongate body including a shapeable portion disposed proximate the proximal end, the shapeable portion being malleable so as to be shaped into a shape and remain in the shape until reshaped. The distal end of the elongate body is advanced into a vasculature of the patient. The shapeable portion of the elongate body is shaped into a first shape that prevents advancement of the guidewire further into the vasculature of the patient.

A guide wire configured for use in medical magnetic resonance applications includes a multi-lumen wire composed of an electrically nonconductive plastic material. The wire extends continuously from a proximal end region to a distal end region of the guide wire and has at least two separate, axially extending hollow channels, and/or at least two coaxial wires arranged coaxially one inside another and extending continuously from a proximal end region to a distal end region of the guide wire. An axially alternating sequence of rod-shaped, elastic stiffening pieces composed of an electrically conductive, nonmagnetic material having higher bending stiffness than the plastic material of the multi-lumen wire, and electrically nonconductive spacer pieces, is arranged in at least one of the hollow channels. At least one of the coaxial wires is constructed from an axially alternating sequence of rod-shaped, elastic stiffening pieces composed of an electrically conductive, nonmagnetic material and electrically nonconductive spacer pieces.

Embodiments of the present disclosure can include a system for steering a guidewire comprising: a guidewire tip integrably connected to a guidewire, the guidewire tip comprising a hollow body having first joint and second joints comprising a plurality of asymmetric recesses in the hollow body; a plurality of tendons operably connected to the first and second joints; and a control unit operably connected to the tendons and configured to actuate the tendons to provide multiple degrees of freedom of movement to the guidewire tip.

A delivery system is disclosed which can be used to deliver an ocular implant into a target location within the eye via an ab interno procedure. In some embodiments, the implant can provide fluid communication between the anterior chamber and the suprachoroidal or supraciliary space while in an implanted state. The delivery system can include a proximal handle component and a distal delivery component. In addition, the proximal handle component can include an actuator to control the release of the implant from the delivery component into the target location in the eye.