A split dilator aspiration system is disclosed. The system includes a catheter, having an elongate, flexible tubular body with a proximal end, a distal end, a side wall defining a central lumen, and a handle on the proximal end. A dilator is advanceable through the central lumen, the dilator having an elongate body, cannulated to receive a guidewire, and an axially extending split along at least a portion of the elongate body, configured to allow removal of a portion of the dilator laterally from the guidewire.

A flow control device may include a housing having a primary valve body defining a primary inlet and an outlet of the flow control device, a secondary valve body defining a secondary inlet of the flow control device, and a chamber defined by an inner circumferential surface of the housing. The primary and secondary inlets may share a common central axis, and a central axis of the outlet may be perpendicularly disposed relative to the common central axis. The chamber may extend between the primary and secondary valve bodies for fluidly connecting the primary and secondary inlets with the outlet. The flow control device may further include a valve member reciprocally mounted in the chamber to (i) block fluid communication between the secondary inlet and the outlet when fluid pressure into the primary inlet is higher than fluid pressure into the secondary inlet, and (ii) block fluid communication between the primary inlet and the outlet when fluid pressure into the secondary inlet is higher than fluid pressure into the primary inlet.

A system for intravascular oxygenation may include a catheter shaft, a vibratory member, and an oxygen source. The catheter shaft may have a wall that extends from a proximal end to a distal end along a longitudinal axis to form a lumen. The distal end may terminate in an atraumatic tip that seals off an interior space of the lumen from an adjacent exterior space. The distal end may include a coiled spring whose coils are tightly disposed against adjacent coils. The vibratory member may be configured to produce and transmit via the wall, to the coiled spring, mechanical vibration or high-frequency acoustic energy. The oxygen source may be configured to be coupled to the proximal end and to deliver a flow of oxygen to an interior space for communication to the exterior space, through gaps that exist or are created between adjacent coils of the coiled spring.

The present disclosure relates to a subcutaneous fixation system for fixing medical devices, in particular catheters, and keeping them in position with respect to an access point on the skin of a patient.

A treatment system for applying negative pressure therapy and fluid instillation treatment to a tissue site, particularly an abdominal tissue site, is disclosed. In some embodiments, the treatment system may include a dressing member, a plurality of fluid removal pathways, a fluid instillation matrix, a drape, a negative-pressure source, and a fluid instillation source. Instillation fluid may be delivered from the fluid instillation source to the tissue site through the fluid instillation matrix, and negative pressure may be communicated and fluid withdrawn from the tissue site through the plurality of fluid removal pathways.

A vacuum aspiration system may be used to treat thromboembolic disease, such as deep vein thrombosis or pulmonary embolism. The system includes a housing, and a fluid flow path extending through the housing. A first catheter is in fluid communication with the flow path, and a connector is configured to place a source of aspiration in communication with the flow path. A clot container is carried by the housing. A hemostasis valve is provided in the housing, and configured to receive a second catheter and direct the second catheter through the first catheter.

An aspiration system exhibits an accelerated drop in negative pressure at the distal end of an aspiration catheter from the time of opening a valve. The system includes an aspiration pump in communication with a first chamber, and an aspiration catheter configured for placement into fluid communication with the first chamber by way of an elongate aspiration tube. A second chamber is provided between the aspiration tube and the catheter, and a valve is provided between the second chamber and the aspiration catheter. Upon opening of the valve with negative pressure at equilibrium in the first and second chambers, resistance to fluid flow between the second chamber and the distal end of the catheter is less than the resistance to fluid flow between the second chamber and the first chamber, causing a rapid aspiration into the second chamber.

A methods of placing large bore aspiration catheters is disclosed. The method of removing a vascular obstruction includes the steps of transvascularly advancing a distal end of an aspiration catheter into proximity with an obstruction, activating a low flow, detection mode of aspiration through the catheter, and thereafter activating a momentary control to activate a high flow, aspiration mode of operation and draw obstructive material into the distal end of the access catheter.

A hemostasis valve may be used with a catheter such as an aspiration catheter. The hemostasis valve comprises a support, and at least a first lever, pivotably carried with respect to the support. A collapsible tubular sidewall defining a valve lumen is carried by the support. A filament is formed into a loop around the tubular sidewall, the filament having at least a first tail portion extending away from the loop to the first lever. A first spring may be configured to move the first lever in a direction that pulls the first tail portion away from the tubular sidewall, reducing the diameter of the valve lumen in response to reducing the diameter of the loop. A second tail portion may extend away from the loop to a second lever. Each tail portion may be attached to its respective lever, or may be slidably advanceable around a fulcrum on the lever and attached with respect to the support.

A split dilator aspiration system is disclosed. The system includes a catheter, having an elongate, flexible tubular body with a proximal end, a distal end, a side wall defining a central lumen, and a handle on the proximal end. A dilator is advanceable through the central lumen, the dilator having an elongate body, cannulated to receive a guidewire, and an axially extending split along at least a portion of the elongate body, configured to allow removal of a portion of the dilator laterally from the guidewire.