Three groups of biocompatible implants were created, to leverage physiological impairment caused by (i) cardiovascular, (ii) renal, and (iii) neuronal diseases. Each group of implants is subdivided into three categories according to extra functionality added plus integrated additions. The first generation contains basic functionality and the second and third generations contain extra functions. Finally, further additions can be combined and integrated. Therefore, the first group comprises of the “First Generation of Cardiovascular Implants” plus the “Second Generation of Cardiovascular Implants” plus the “Third Generation of Cardiovascular Implants” plus additional integrations named “Additions”. Equally, the second group comprises of the “First”, the “Second” and the “Third” Generation of Renal Prosthetics plus Additions. The same categorisation applies to Neural Implants, which are three generations plus additions. This can be found in the description of claims presented in the Austrian Prio (provisional patent application) number A 60273/2019, from 11 Dec. 2019.

Three groups of biocompatible implants were created, to leverage physiological impairment caused by (i) cardiovascular, (ii) renal, and (iii) neuronal diseases. Each group of implants is subdivided into three categories according to extra functionality added plus integrated additions. The first generation contains basic functionality and the second and third generations contain extra functions. Finally, further additions can be combined and integrated. Therefore, the first group comprises of the “First Generation of Cardiovascular Implants” plus the “Second Generation of Cardiovascular Implants” plus the “Third Generation of Cardiovascular Implants” plus additional integrations named “Additions”. Equally, the second group comprises of the “First”, the “Second” and the “Third” Generation of Renal Prosthetics plus Additions. The same categorisation applies to Neural Implants, which are three generations plus additions. This can be found in the description of claims presented in the Austrian Prio (provisional patent application) number A 60273/2019, from 11 Dec. 2019.

The invention relates to a container (1, 1′, 1″) for a heart pump device (4, 8, 12, 17, 18, 19, 26) with a first receiving space (3) for a compressible and expandable heart pump (4), wherein the first receiving space is delimited on several sides, in particular on all sides, by one or more closure elements (5, 5′, 6, 6′ 6″) and is closed off to the outside for preventing a contacting of the heart pump, wherein the closure elements (5, 5′, 6, 6′ 6″) leave free an opening (7) for the passage of a catheter (8) from the outside into the first receiving space (3), wherein the diameter of the opening (7) is dimensioned such that the heart pump can pass this exclusively in a condition which is at least partly compressed compared to the expanded condition. For implantation, the heart pump in the container (1, 1′, 1″) can firstly be operated by trial in the container (1, 1′, 1″) whilst feeding a rinsing fluid and can then be pulled through the opening (7) amid simultaneous compression, into a sheath element (11).

A device, a kit and a method is presented for permanently augmenting the pump function of the left heart. The mitral valve plane is assisted in a movement along the left ventricular long axis during each heart cycle. The very close relationship between the coronary sinus and the mitral valve is used by various embodiments of a medical device providing this assisted movement. By means of catheter technique an implant is inserted into the coronary sinus, the device is augmenting the up and down movement of the mitral valve and thereby increasing the left ventricular diastolic filling when moving upwards and the piston effect of the closed mitral valve when moving downwards.

An implantable pump system is provided, suitable for use as a left ventricular assist device (LVAD) system, having an implantable pump, a battery, a controller, and a programmer. The implantable pump includes a flexible membrane coupled to an actuator assembly via a skirt that extends toward the inlet of the pump and curves to guide blood toward the outlet. The actuator assembly is magnetically engageable with electromagnetic coils, so that when the electromagnetic coils are energized, the actuator assembly causes wavelike undulations to propagate along the flexible membrane to propel blood from the inlet, across the skirt, and through the outlet of the implantable pump. The controller may be programmed by a programmer to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while operating in an efficient manner that avoids thrombus formation, hemolysis and/or platelet activation.

An implantable pump system is provided, suitable for use as a left ventricular assist device (LVAD) system, having an implantable pump, a battery, a controller, and a programmer. The implantable pump includes a flexible membrane coupled to an actuator assembly via a skirt that extends toward the inlet of the pump and curves to guide blood toward the outlet. The actuator assembly is magnetically engageable with electromagnetic coils, so that when the electromagnetic coils are energized, the actuator assembly causes wavelike undulations to propagate along the flexible membrane to propel blood from the inlet, across the skirt, and through the outlet of the implantable pump. The controller may be programmed by a programmer to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while operating in an efficient manner that avoids thrombus formation, hemolysis and/or platelet activation.

A blood pump for causing blood to flow in one direction is used for a blood oxidation system that circulates blood in a body to an oxidizer so as to supply oxygen into the body from outside the body. The blood pump includes an outer wall having a gas outlet port formed through a lateral surface thereof; a blood chamber having a pouch which is inserted into the outer wall and of which opposite ends are connected to opposite ends of the outer wall, respectively; a pump injection valve fluid-communicably coupled to one end of the blood chamber and blocking blood from flowing to the blood chamber; and a pump discharge valve fluid-communicably coupled to the other end of the blood chamber and blocking blood from flowing from the blood chamber.

A method for influencing cerebral perfusion in a patient by modifying a volume of a volume adaptor introduced into a cerebral ventricle of the patient, the method comprising identifying a timing of a cerebral blood inflow and/or outflow in a cardiac activity of the patient, modifying a volume of the volume adaptor in synchronization to the identified timing of the cerebral blood flow, to an amount sufficient to modify an intracranial pressure in the cerebral ventricle, such that a flow of the cerebral blood flow is enhanced. In some exemplary embodiments of the invention, the inflation duration of the volume adapter is short relative to the cardiac cycle.

A pump system is provided comprising a diaphragm fluid pump which can be fluidically connected to a heart and/or at least one blood vessel by means of an inlet cannula and an outlet cannula and is adapted for generating a pulsatile fluid flow for supporting a cardiac activity of the heart, a working pressure source connected to the diaphragm fluid pump by means of a pressure line and adapted for providing a working pressure for driving the diaphragm fluid pump, a control unit adapted for controlling the working pressure, a first flow sensor adapted for detecting a first cannula flow signal corresponding to an inlet flow in the inlet cannula or an outlet flow in the outlet cannula, a working pressure sensor adapted for detecting a working pressure signal corresponding to the working pressure in the pressure line.

A pump system is provided comprising a diaphragm fluid pump which can be fluidically connected to a heart and/or at least one blood vessel by means of an inlet cannula and an outlet cannula and is adapted for generating a pulsatile fluid flow for supporting a cardiac activity of the heart, a working pressure source connected to the diaphragm fluid pump by means of a pressure line and adapted for providing a working pressure for driving the diaphragm fluid pump, a control unit adapted for controlling the working pressure, a first flow sensor adapted for detecting a first cannula flow signal corresponding to an inlet flow in the inlet cannula or an outlet flow in the outlet cannula, a working pressure sensor adapted for detecting a working pressure signal corresponding to the working pressure in the pressure line.