A blood flow assist system can include an impeller assembly including an impeller shaft and an impeller on the impeller shaft, a primary flow pathway disposed along an exterior surface of the impeller. The system can include a rotor assembly at a proximal portion of the impeller shaft. A secondary flow pathway can be disposed along a lumen of the impeller shaft. During operation of the blood flow assist system, blood can be pumped proximally along the primary flow pathway and the secondary flow pathway. The system can include a sleeve bearing distal the impeller. The system can include a drive unit having a distal end disposed distal a proximal end of the second impeller. The drive unit comprising a drive magnet and a drive bearing between the drive magnet and the impeller assembly.

A blood flow assist system can include an impeller assembly including an impeller shaft and an impeller on the impeller shaft, a primary flow pathway disposed along an exterior surface of the impeller. The system can include a rotor assembly at a proximal portion of the impeller shaft. A secondary flow pathway can be disposed along a lumen of the impeller shaft. During operation of the blood flow assist system, blood can be pumped proximally along the primary flow pathway and the secondary flow pathway. The system can include a sleeve bearing distal the impeller. The system can include a drive unit having a distal end disposed distal a proximal end of the second impeller. The drive unit comprising a drive magnet and a drive bearing between the drive magnet and the impeller assembly.

A catheter pump assembly is provided. The catheter pump assembly includes a proximal portion, a distal portion, a catheter body having a lumen extending along a longitudinal axis between the proximal and distal portions, an impeller disposed at the distal portion, and a stator disposed at a downstream location of the impeller to straighten flow downstream from the impeller. The stator is collapsible from a deployed configuration to a collapsed configuration.

A catheter pump assembly is provided. The catheter pump assembly includes a proximal portion, a distal portion, a catheter body having a lumen extending along a longitudinal axis between the proximal and distal portions, an impeller disposed at the distal portion, and a stator disposed at a downstream location of the impeller to straighten flow downstream from the impeller. The stator is collapsible from a deployed configuration to a collapsed configuration.

In various embodiments, a catheter pump is disclosed herein. The catheter pump can include an elongated catheter body having a distal portion including an expandable cannula having an inlet and an outlet. The expandable cannula can have a delivery profile and an operational profile larger than the delivery profile. An impeller assembly can include an impeller shaft, and an impeller body can include one or more blades. The impeller blades can draw blood into the cannula when rotated. Further, an expandable support can have a mounting portion disposed on the impeller shaft distal of the impeller body and a cannula contact portion for reducing a change in tip gap due to bending of the cannula. The cannula contact portion can be disposed distal of the mounting portion.

This invention relates to an intravascular blood pump, comprising a pumping device with a pump section and a drive section, wherein the pump section comprises a pump casing having a primary blood flow inlet and a primary blood flow outlet hydraulically connected by a primary passage and the drive section comprises a stator and a rotor rotatable about an axis of rotation and configured to rotate a primary impeller, the primary impeller being configured to convey a primary blood flow from the primary blood flow inlet to the primary blood flow outlet along the primary passage, the drive section further comprises an ancillary blood flow inlet and an ancillary blood flow outlet hydraulically connected by an ancillary passage extending through an axial gap between the rotor and the stator and an ancillary impeller arranged at a drive section end (DSE) of the rotor and rotatable about the axis of rotation along with the rotor, the ancillary impeller comprising one or more ancillary impeller vanes configured to convey an ancillary blood flow (ABF) from the ancillary blood flow inlet to the ancillary blood flow outlet along the ancillary passage in a direction toward a pump section end (PSE) of the pumping device, and the rotor is mounted in a blood-purged radial sliding rotor bearing with an inner rotor bearing surface and an outer rotor bearing surface, and the ancillary impeller forms the inner rotor bearing surface of the radial sliding rotor bearing.

This invention relates to an intravascular blood pump, comprising a pumping device with a pump section and a drive section, wherein the pump section comprises a pump casing having a primary blood flow inlet and a primary blood flow outlet hydraulically connected by a primary passage and the drive section comprises a stator and a rotor rotatable about an axis of rotation and configured to rotate a primary impeller, the primary impeller being configured to convey a primary blood flow from the primary blood flow inlet to the primary blood flow outlet along the primary passage, the drive section further comprises an ancillary blood flow inlet and an ancillary blood flow outlet hydraulically connected by an ancillary passage extending through an axial gap between the rotor and the stator and an ancillary impeller arranged at a drive section end (DSE) of the rotor and rotatable about the axis of rotation along with the rotor, the ancillary impeller comprising one or more ancillary impeller vanes configured to convey an ancillary blood flow (ABF) from the ancillary blood flow inlet to the ancillary blood flow outlet along the ancillary passage in a direction toward a pump section end (PSE) of the pumping device, and the rotor is mounted in a blood-purged radial sliding rotor bearing with an inner rotor bearing surface and an outer rotor bearing surface, and the ancillary impeller forms the inner rotor bearing surface of the radial sliding rotor bearing.

To provide biotechnological filtration possibilities with which the danger of contamination is low and at the same time an optimum flow profile can be achieved, the use of a filter module 100 is proposed, the latter having, in a filter housing 110, a filter, with a bundle of hollow fibres 114, and a centrifugal pump rotor 132, for a biotechnological production method, and a filter module 100 for the filtration of a biotechnological liquid L, having a filter housing 110, a filter arranged in the filter housing 110 with a bundle of hollow fibres 114, a centrifugal pump rotor 132 arranged in the filter housing 110 such that it is fluidically connected to the interior of the hollow fibres 114, wherein the centrifugal pump rotor 132 is able to be magnetically driven such that it can force a liquid L through the hollow fibres 114, a first port 102 for the supply of a biotechnological liquid L to be filtered, which first port 102 is fluidically connected to the interior of the hollow fibres 114 of the filter, a second port 104 for the removal of a biotechnological liquid L to be filtered, which second port 104 is fluidically connected to the interior of the hollow fibres 114 of the filter, and a third port 107 for the removal of precipitated waste liquid, which third port 107 is fluidically connected to the exterior of the hollow fibres 114, and a filtration device 1100, 1200, 1300 having a filter module 100, which is able to be coupled to a drive unit, and a drive unit for magnetically driving the centrifugal pump rotor 132 of the filter module 100, which drive unit can generate dynamic magnetic fields for magnetically driving and magnetically supporting the centrifugal pump rotor 132 when the filter module 100 is coupled to the drive module.

To provide biotechnological filtration possibilities with which the danger of contamination is low and at the same time an optimum flow profile can be achieved, the use of a filter module 100 is proposed, the latter having, in a filter housing 110, a filter, with a bundle of hollow fibres 114, and a centrifugal pump rotor 132, for a biotechnological production method, and a filter module 100 for the filtration of a biotechnological liquid L, having a filter housing 110, a filter arranged in the filter housing 110 with a bundle of hollow fibres 114, a centrifugal pump rotor 132 arranged in the filter housing 110 such that it is fluidically connected to the interior of the hollow fibres 114, wherein the centrifugal pump rotor 132 is able to be magnetically driven such that it can force a liquid L through the hollow fibres 114, a first port 102 for the supply of a biotechnological liquid L to be filtered, which first port 102 is fluidically connected to the interior of the hollow fibres 114 of the filter, a second port 104 for the removal of a biotechnological liquid L to be filtered, which second port 104 is fluidically connected to the interior of the hollow fibres 114 of the filter, and a third port 107 for the removal of precipitated waste liquid, which third port 107 is fluidically connected to the exterior of the hollow fibres 114, and a filtration device 1100, 1200, 1300 having a filter module 100, which is able to be coupled to a drive unit, and a drive unit for magnetically driving the centrifugal pump rotor 132 of the filter module 100, which drive unit can generate dynamic magnetic fields for magnetically driving and magnetically supporting the centrifugal pump rotor 132 when the filter module 100 is coupled to the drive module.

An interventional ventricular assist device (100), including: an interventional tube (10). a motor assembly (30), a perfusion cylinder (40), and an impeller assembly (20). The interventional tube (10) has a liquid inlet (11) and a liquid outlet (12). The impeller assembly (20) includes an impeller (21), accommodated within the interventional tube (10) and rotatable to enable a liquid to flow into the interventional tube (10) via the liquid inlet (11) and out therefrom via the liquid outlet (12). The motor assembly (30) is configured to generate a rotating magnetic field to drive the impeller (21) to rotate and generate an attraction to the impeller (21). A perfusate injected from the perfusion cylinder (40) is adapted to provide a thrust to the impeller assembly (20), whereby the impeller (21) is suspendedly rotatable in the interventional tube (10) under a combined action of the thrust and the attraction.