An extension cannula for use with a conventional ECMO return cannula is provided. The extension cannula includes a flexible conduit transitionable between a collapsed insertion state and an expanded deployed state when in communication with blood flow from an ECMO machine via the ECMO return cannula. The extension cannula may be positioned through a conventional ECMO return cannula such that the proximal end of the flexible conduit is disposed within and proximal to the end of the ECMO return cannula, while the distal end of the flexible conduit is disposed in a patient's thoracic aorta to deliver oxygenated blood directly to the patient's thoracic aorta via one or more pores at the distal region of the flexible conduit to improve cerebral oxygenation, maintain systemic arterial pulsatility, and reduce the potential for end-organ injury.

An aortic adapter assembly is provided, including a T-shaped flow connector, including: an inserted conduit portion, having a blood-contacting surface which is smooth; an extruded neck portion, wherein the inserted conduit portion is joined with the extruded neck portion; and a truss, disposed in the inserted conduit portion; wherein the T-shaped flow connector has a polymeric elastomer reinforced by the truss having a Nitinol material; wherein the inserted conduit portion has an inner wall which is gradually thinning at two conduit ends of the inserted conduit portion, with a proper distance of a tip of the conduit end to the outmost boundary of the truss, and the conduit end possesses a compliance-matching effect to an implant site artery; wherein a proximal end of the extruded neck portion is configured to be joined with an inlet adapter of a blood pump. The aortic adapter assembly is accompanied with a quick-connector type coupler and a deployment method to accomplish an insertion type flow communication between a ventricular assist device and the human circulation.

An aortic adapter assembly is provided, including a T-shaped flow connector, including: an inserted conduit portion, having a blood-contacting surface which is smooth; an extruded neck portion, wherein the inserted conduit portion is joined with the extruded neck portion; and a truss, disposed in the inserted conduit portion; wherein the T-shaped flow connector has a polymeric elastomer reinforced by the truss having a Nitinol material; wherein the inserted conduit portion has an inner wall which is gradually thinning at two conduit ends of the inserted conduit portion, with a proper distance of a tip of the conduit end to the outmost boundary of the truss, and the conduit end possesses a compliance-matching effect to an implant site artery; wherein a proximal end of the extruded neck portion is configured to be joined with an inlet adapter of a blood pump. The aortic adapter assembly is accompanied with a quick-connector type coupler and a deployment method to accomplish an insertion type flow communication between a ventricular assist device and the human circulation.

A device for circulatory support of the heart with holding means implanted intracardially in the left or right ventricular outflow of the hea by catheter, using an endovascular method, through a femoral access or a percutaneous transventricular, transseptal, transapical or transvenous access, the holding means comprises anchoring means fixed in the subcommissural triangle underneath the aortic valve and the pulmonary valve, in the flow direction of the blood on the ventricular side of the aortic valve and the pulmonary valve, a pump fixed in the holding means by a catheter, using an endovascular method, through a femoral access or a percutaneous transventricular, transseptal, transapical or transvenous access, the pump could be inserted releasably into the holding means after the holding means has been fixed by the anchoring means in the subcommissural triangles underneath the aortic valve and the pulmonary valve, or is connected to the collapsible and expandable anchoring means.

A cannula system is provided. The system may comprise: a cannula having a hose element having front and rear end regions, wherein a channel extends from the front end region to the rear end region, a hollow body having a front end region, and a connector which, in a connected state of the cannula system in which the front end region of the hollow body is introduced into the channel of the hose element, receives the front end region of the hose element and the front end region of the hollow body in an inner region of the connector. The connector may exert clamping forces on the front end region of the hose element and clamp the front end region of the hose element between the front end region of the hollow body and the connector. Also provided is a blood pump system including such a cannula system.

A cannula system is provided. The system may comprise: a cannula having a hose element having front and rear end regions, wherein a channel extends from the front end region to the rear end region, a hollow body having a front end region, and a connector which, in a connected state of the cannula system in which the front end region of the hollow body is introduced into the channel of the hose element, receives the front end region of the hose element and the front end region of the hollow body in an inner region of the connector. The connector may exert clamping forces on the front end region of the hose element and clamp the front end region of the hose element between the front end region of the hollow body and the connector. Also provided is a blood pump system including such a cannula system.

An implantable cardiovascular blood pump system is provided, suitable for use as a left ventricular assist device (LVAD) system, having an implantable cardiovascular pump, an extracorporeal battery and a controller coupled to the implantable pump, and a programmer selectively periodically coupled to the controller to configure and adjust operating parameters of the implantable cardiovascular pump. The implantable cardiovascular blood pump includes a coaxial inflow cannula and outflow cannula in fluid communication with one another and with a pumping mechanism. The pumping mechanism may be a vibrating membrane pump which may include a flexible membrane coupled to an electromagnetic actuator assembly that causes wavelike undulations to propagate along the flexible membrane to propel blood through the implantable cardiovascular pump. The implantable cardiovascular pump may be programmed to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while avoiding thrombus formation, hemolysis and/or platelet activation.

An implantable cardiovascular blood pump system is provided, suitable for use as a left ventricular assist device (LVAD) system, having an implantable cardiovascular pump, an extracorporeal battery and a controller coupled to the implantable pump, and a programmer selectively periodically coupled to the controller to configure and adjust operating parameters of the implantable cardiovascular pump. The implantable cardiovascular blood pump includes a coaxial inflow cannula and outflow cannula in fluid communication with one another and with a pumping mechanism. The pumping mechanism may be a vibrating membrane pump which may include a flexible membrane coupled to an electromagnetic actuator assembly that causes wavelike undulations to propagate along the flexible membrane to propel blood through the implantable cardiovascular pump. The implantable cardiovascular pump may be programmed to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while avoiding thrombus formation, hemolysis and/or platelet activation.

A connecting device is provided for connecting a pipe or tube-shaped element to the heart or a blood vessel of a patient, comprising a suture ring that has an opening, which can be closed by means of a closure element and through which said pipe or tube-shaped element is guided in the axial direction. The closure element is secured to the suture ring by means of at least one elastic securing element. A radially-expandable sealing element can also be provided in order to establish a sealing placement of the closure element against the suture ring.

A connecting device is provided for connecting a pipe or tube-shaped element to the heart or a blood vessel of a patient, comprising a suture ring that has an opening, which can be closed by means of a closure element and through which said pipe or tube-shaped element is guided in the axial direction. The closure element is secured to the suture ring by means of at least one elastic securing element. A radially-expandable sealing element can also be provided in order to establish a sealing placement of the closure element against the suture ring.