An implantable pump includes a rigid housing with an oblate spheroid shape and having an inner chamber divided by a movable elastomeric membrane into a gas sub-chamber which is connectible through a drive line to an external pneumatic source, and a blood sub-chamber which is connectible through a graft assembly to an anatomical heart. The housing includes a blood port opening oriented at an angle and at the upper apex of the housing and connected to the blood sub-chamber, and a gas port opening to the gas sub-chamber that is situated at a lower apex of the housing. The pump is provided with a drive line that includes a gas conduit and a heart sensor, the drive line connectible to a drive system that is capable of delivering gas flow through the drive line gas conduit in response to signals driven by the heart sensor.

An implantable pump includes a rigid housing with an oblate spheroid shape and having an inner chamber divided by a movable elastomeric membrane into a gas sub-chamber which is connectible through a drive line to an external pneumatic source, and a blood sub-chamber which is connectible through a graft assembly to an anatomical heart. The housing includes a blood port opening oriented at an angle and at the upper apex of the housing and connected to the blood sub-chamber, and a gas port opening to the gas sub-chamber that is situated at a lower apex of the housing. The pump is provided with a drive line that includes a gas conduit and a heart sensor, the drive line connectible to a drive system that is capable of delivering gas flow through the drive line gas conduit in response to signals driven by the heart sensor.

A connecting device is provided for connecting a pipe or tube-shaped element to the heart or a blood vessel of a patient, comprising a suture ring that has an opening, which can be closed by means of a closure element and through which said pipe or tube-shaped element is guided in the axial direction. The closure element is secured to the suture ring by means of at least one elastic securing element. A radially-expandable sealing element can also be provided in order to establish a sealing placement of the closure element against the suture ring.

A connecting device is provided for connecting a pipe or tube-shaped element to the heart or a blood vessel of a patient, comprising a suture ring that has an opening, which can be closed by means of a closure element and through which said pipe or tube-shaped element is guided in the axial direction. The closure element is secured to the suture ring by means of at least one elastic securing element. A radially-expandable sealing element can also be provided in order to establish a sealing placement of the closure element against the suture ring.

An extension cannula and in-line connector for use with a conventional ECMO return cannula is provided. The extension cannula includes a flexible conduit transitionable between a collapsed insertion state and an expanded deployed state when in communication with blow flow from an ECMO machine via the ECMO return cannula. The extension cannula may be positioned through a conventional ECMO return cannula such that the proximal end of the flexible conduit is disposed within and proximal to the end of the ECMO return cannula, while the distal end of the flexible conduit is disposed in a patient's thoracic aorta to deliver oxygenated blood directly to the patient's thoracic aorta via one or more pores at the distal region of the flexible conduit to improve cerebral oxygenation, maintain systemic arterial pulsatility, and reduce the potential for end-organ injury.

Disclosed is a cannula (CA1 to CA7) for endovascular and/or jugular blood circuit support, comprising: —a proximal portion (PP1 to PP6), —a distal portion (DP1 to DP7) that comprises at least one distal opening (DO1 to DO7), —a lumen portion (LP) that extends from the proximal portion (PP1 to PP6) to the at least one distal opening (DO1 to DO7), and—at least one intermediate portion (IP1 to IP7) that is arranged between the proximal portion (PP1 to PP6) and the distal portion (DP1 to DP7), wherein the intermediate portion (IP1 to IP7) comprises at least one intermediate opening (IO1 to IO7), and wherein the intermediate portion (IP1 to IP7) is configured such that more than 90 volume percent of the fluid flow are drained from the intermediate opening (IO1 to IO7) if a fluid flow within the proximal portion (PP1 to PP6) is directed proximally and such that more than 90 volume percent of the fluid flow are delivered through the at least one distal opening (DO1 to DO7) if a fluid flow within the proximal portion (PP1 to PP6) is directed distally.

An arrangement (200 to 1200) is provided for transporting a liquid (B) through a cannula system (CS), comprising: a liquid guiding system (LGS) comprising at least three separated portions (SP2a, SP2b, SP3c) which define separate liquid guiding portions of the liquid guiding system (LGS), and a connecting portion (CP2 to CP12) which fluidically connects the at least three separated portions (SP2a, SP2b, SP3c) and which comprises a lumen that branches out into at least two lumens, wherein the liquid guiding system (LGS) is configured to be connected to a pump arrangement (Arr2 to An12) which drives a flow of the liquid (B), and wherein the liquid guiding system (LGS) is configured to be connected to a cannula system (CS) which is adapted to be inserted into a body of a human or of an animal and which comprises an inflow opening and an outflow opening of the liquid guiding system (LGS).

An arrangement (200 to 1200) is provided for transporting a liquid (B) through a cannula system (CS), comprising: a liquid guiding system (LGS) comprising at least three separated portions (SP2a, SP2b, SP3c) which define separate liquid guiding portions of the liquid guiding system (LGS), and a connecting portion (CP2 to CP12) which fluidically connects the at least three separated portions (SP2a, SP2b, SP3c) and which comprises a lumen that branches out into at least two lumens, wherein the liquid guiding system (LGS) is configured to be connected to a pump arrangement (Arr2 to An12) which drives a flow of the liquid (B), and wherein the liquid guiding system (LGS) is configured to be connected to a cannula system (CS) which is adapted to be inserted into a body of a human or of an animal and which comprises an inflow opening and an outflow opening of the liquid guiding system (LGS).

Embodiments of the present invention provide an extra corporeal membrane oxygenation circuit, wherein a pump communicates blood from a patient to an oxygenator and thence back to the patient, comprising: (a) a medium diameter venous line configured to accept blood from the patient and communicate the blood to the pump; (b) a medium diameter arterial line configured to accept blood from the oxygenator and communicate the blood to the patient; (c) one or more shunts connected in a series, where each shunt comprises a medium diameter input connected to a medium diameter output, where the medium diameter output is configured to connect to a medium diameter input of a successive shunt; a small diameter outlet between the medium diameter input and the medium diameter output; and a stopcock connected to the small diameter output such that flow out of the small diameter outlet can be controlled by the stopcock; wherein a first of such shunts is connected to accept blood from the venous line in parallel with the pump and wherein a last of such shunts is connected to communicate blood to the arterial line.

An inflow cannula assembly intended for connecting a ventricular assist device (VAD) to a heart chamber without suturing anastomosis is provided. The inflow cannula assembly includes a deformable flow cannula with funnel-shaped bellmouth intake at a first end and a second end interfaced to the inlet of a VAD with minimal interface discontinuity; also includes is a pair of male and female fasteners that can be screw locked to fix and seal the cannula bellmouth against the endocardium for hemostasis purpose; as well as a VAD coupler and a VAD inlet adapter that enable a quick connection of the cannula with the VAD.