An access device for a heart chamber, a removable hemostatic valve unit, and a system including a cardiac assist unit are disclosed. In examples, the access device) includes an apical base plate and a sealing unit configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.

An access device for a heart chamber, a removable hemostatic valve unit, and a system including a cardiac assist unit are disclosed. In examples, the access device) includes an apical base plate and a sealing unit configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.

An apical cuff axial compression assembly including a ring member for coupling an apical cuff of a Ventricular Assist Device pump, to left ventricular apical tissue. Tissue anchors are employed to engage with the ring member and the apical cuff to exert direct or axial compression of the ring member to the apical cuff and to the left ventricular apical tissue. A first variant includes an axial compression ring and a plurality of openings to accommodate the tissue anchors. A second variant includes a segmented axial compression ring composed of a plurality of arcuate members, which may be contiguous or joined to each other or not. Each of the plurality of arcuate members has at least one tissue anchor opening passing there through.

An apical cuff axial compression assembly including a ring member for coupling an apical cuff of a Ventricular Assist Device pump, to left ventricular apical tissue. Tissue anchors are employed to engage with the ring member and the apical cuff to exert direct or axial compression of the ring member to the apical cuff and to the left ventricular apical tissue. A first variant includes an axial compression ring and a plurality of openings to accommodate the tissue anchors. A second variant includes a segmented axial compression ring composed of a plurality of arcuate members, which may be contiguous or joined to each other or not. Each of the plurality of arcuate members has at least one tissue anchor opening passing there through.

An inflow cannula assembly intended for connecting a ventricular assist device (VAD) to a heart chamber without suturing anastomosis is provided. The inflow cannula assembly includes a deformable flow cannula with funnel-shaped bellmouth intake at a first end and a second end interfaced to the inlet of a VAD with minimal interface discontinuity; also includes is a pair of male and female fasteners that can be screw locked to fix and seal the cannula bellmouth against the endocardium for hemostasis purpose; as well as a VAD coupler and a VAD inlet adapter that enable a quick connection of the cannula with the VAD.

A para-aortic blood pump device includes a blood pump, an aortic adapter, a driveline, and a driver. The blood pump includes a blood sac, a pump housing and a pressure sensor, whereas the pressure sensor is installed in the pump housing for monitoring the blood pressure inside the blood pump. The aortic adapter is a T-manifold shaped conduit connected to the blood pump and is used for connecting the blood pump with human aorta to facilitate circulatory support. The driveline allows a pneumatic communication to the blood pump in addition to transmitting the electrical blood pressure signal to the driver. The driver receives and processes the electrical blood pressure signal, decides the timing, speed and duration of blood pump fill and eject actions so as to provide counter-pulsatile circulatory support to assist human circulation.

An implantable circulatory support system, configured to connect a ventricular chamber of a heart, including a valveless displacement blood pump, a deformable polymeric flow cannula, a pair of male and female fasteners, a coupler, a driveline assembly, and a co-pulsatile driver. Forward and backward flow communication between the blood pump and the heart chamber is accomplished using the present flow cannula invention which is anastomosed to the heart chamber in a sutureless manner. When providing circulatory support, the co-pulsatile driver ejects blood out of the blood pump during systolic ventricular contraction and fills the blood pump with blood during diastolic ventricular relaxation.

An implantable circulatory support system, configured to connect a ventricular chamber of a heart, including a valveless displacement blood pump, a deformable polymeric flow cannula, a pair of male and female fasteners, a coupler, a driveline assembly, and a co-pulsatile driver. Forward and backward flow communication between the blood pump and the heart chamber is accomplished using the present flow cannula invention which is anastomosed to the heart chamber in a sutureless manner. When providing circulatory support, the co-pulsatile driver ejects blood out of the blood pump during systolic ventricular contraction and fills the blood pump with blood during diastolic ventricular relaxation.

In one general aspect, a cuff for attachment to a heart includes an attachment component configured to engage a blood pump to attach the cuff to the blood pump and a sewing ring for attachment to the heart. The sewing ring is coupled to the attachment component, and the attachment component and the sewing ring each define a central opening configured to admit an inflow cannula of a blood pump. The sewing ring comprises a member that provides rigidity to flatten a portion of a myocardium of the heart when the cuff is attached to the heart.

Methods, systems, and devices for a mechanical circulatory support system are disclosed herein. An implantable power supply can be part of a mechanical circulatory support system. The implantable power supply can include one or several energy storage components, a power source, a voltage converter, and an output bus. Power can be provided to the voltage converter from one or both of the power source and the first energy storage component. The voltage converter can convert the voltage of the power from a first voltage to a second voltage and can power the output bus.