A method of providing vagus nerve stimulation to a user is provided. The method includes the step of prompting, via a first audio cue emitted by an earpiece worn by a user, the user to inhale at a first point in time. The method may further include the step of prompting, via a second audio cue emitted by the earpiece, the user to exhale at a second point in time. The method may further include the step of stimulating a vagus nerve of the user with a first electrical signal generated by the earpiece at the second point in time. The first electrical signal may be applied to a concha of an ear of the user. The first electrical signal may be applied to an ear canal of the user. The first electrical signal may be applied to a tragus of the user.

A patch for a therapeutic electrical stimulation device includes a shoe connected to the first side of the patch, the shoe including a body extending in a longitudinal direction from a first end to a second end, and having first and second surfaces, the first end of the shoe defining at least two ports, and the first surface of the shoe defining a connection member. The patch also includes at least one conductor positioned in the ports of the first end of the shoe. The shoe is configured for sliding insertion into a receptacle defined by a controller so that the conductor is connected to the controller to deliver electrical current from the controller, through the conductor, and to the electrodes, and the connection member is at least partially captured by a detent defined by the controller in the receptacle to retain the shoe within the receptacle.

A method and system for providing stimulation to a user, the method including: transitioning a stimulation device from a baseline state to a first impedance monitoring state; during the first impedance monitoring state, guiding, an adjustment of a position of the stimulation device at a head region of the user to satisfy a first impedance criterion; upon satisfaction of the first impedance criterion, transitioning the stimulation device from the first impedance monitoring state to a stimulation regime that comprises a second monitoring state having a second criterion; upon detection of failure to satisfy the second criterion, transitioning the stimulation device from the stimulation regime to the first impedance monitoring state; and upon detecting that a third impedance criterion of the first impedance monitoring state is satisfied, transitioning the stimulation device from the first impedance monitoring state to the stimulation regime.

Disclosed are methods and devices utilizing bioelectrodynamics for the therapeutic treatment of disorders in a subject in need thereof with an electric field or electromagnetic field therapy. The methods and devices provide an inhibitory effect on growth of cancer cells that are exposed to an electromagnetic field generated by a CETS unit. Cancer cells may arrest proliferation and enter apoptosis by activation of the unfolded protein response (UPR), TNF/TRAIL, and p53 oncogene activation. The methods and devices may be used to enhance wound healing with exposure to an electromagnetic field generated by a CETS unit. Noncancerous cells may show a significant increase in cell migration with no activation of apoptosis pathways.

An implantable medical device (IMD) can include a cardiac pacemaker or an implantable cardioverter-defibrillator (ICD). Various portions of the IMD, such as a device body, a lead body, or a lead tip, can be provided to reduce or dissipate a current and heat induced by various external environmental factors. According to various embodiments, features can be incorporated into the lead body, the lead tip, or the IMD body to reduce the creation of an induced current, or dissipate the induced current and heat created due to an induced current in the lead. For example, an IMD can include at least one outer conductive member and a first electrode. The first electrode can be in electrical communication with the at least one outer conductive member. The first electrode can dissipate a current induced in the at least one outer conductive member via a first portion of the anatomical structure.

A multi-functional integrated skin beauty device according to the present invention is formed by comprising a mist treatment part generating sterilization water by electrolyzing water in a water tank and spraying the generated sterilization water in a mist shape, a temperature stimulation treatment part applying a temperature stimulation to skin, an EP treatment part applying an electric signal to an EP electrode; and a light treatment part outputting a light for skin care. A housing forming an exterior appearance of the multi-functional integrated skin beauty device includes a pillar-type handle part graspable by a user with one hand, and a first head part and a second head part protruded from an upper end of the handle part toward both lateral surfaces.

A device for applying electrical stimulation to a surface of the human body utilizes a calibrated, pre-arranged pattern of conducting, current emitting elements to distribute current throughout an entire surface at once, such as human face, without needing to alter the device to accommodate various are sizes, including varying face sizes.

Hand-controlled physiotherapy equipment contains: a first electrode and a second electrode which are connected with living creatures so as to form a closed loop, an electrical stimulation system, a signal receiving unit, and a signal identification unit. The electrical stimulation system includes a sensing unit. The signal receiving unit is connected with the sensing unit in a wired manner or a wireless manner, the signal identification unit is configured to transform loop signals into time series signals, wherein when each of the time series signals has a specific interruption signal and a specific recovery signal, each time series signal triggers a mode adjustment signal in a control module. The control module includes a predetermined comparison database, and the comparison database has multiple set modes, wherein the multiple set modes respectively have multiple interruption signals and multiple recovery signals.

A method and system for providing stimulation to a user, the method including: transitioning a stimulation device from a baseline state to a first impedance monitoring state; during the first impedance monitoring state, guiding, an adjustment of a position of the stimulation device at a head region of the user to satisfy a first impedance criterion; upon satisfaction of the first impedance criterion, transitioning the stimulation device from the first impedance monitoring state to a stimulation regime that comprises a second monitoring state having a second criterion; upon detection of failure to satisfy the second criterion, transitioning the stimulation device from the stimulation regime to the first impedance monitoring state; and upon detecting that a third impedance criterion of the first impedance monitoring state is satisfied, transitioning the stimulation device from the first impedance monitoring state to the stimulation regime.

This disclosure provide a nanopillar electrode device, comprising a substrate patterned with a plurality of metal pads. The device may further comprise a plurality of nanopillars electrode arrays, wherein each nanopillar electrode array is attached to the substrate above a metal pad and electrically connected to the pad. The device may further comprise and a chamber surrounding the nanopillar electrodes, which can be used for culturing cells of interest for recording action potentials. The nanopillar electrode device may be configured to apply a voltage through the nanopillar electrodes from a voltage source. Nanopillar electroporation may be used to increase the permeability of cell membranes to allow intracellular recording. Also provided are methods of device fabrication, and methods of use.