A method for identifying reversible cardiac dyssynchrony (RCD) of a patient and treating the RCD measures an event relating to a rapid increase in the rate of pressure increase within the left ventricle. The method calculates a first time delay between the event and a first reference time. If the first time delay is longer than a set fraction of electrical activation of the heart, then the presence of cardiac dyssynchrony in the patient is identified. Pacing is applied to the heart, and a second time delay between the event following pacing and a second reference time following pacing is calculated. If the second time delay is shorter than the first time delay, the method identifies a shortening of a delay to onset of myocardial synergy, OoS, thereby identifying the presence of RCD in the patient. Treatment of the RCD is performed.

A preferred method to obtain painless or near painless needle 8 penetration is disclosed to be in the following manner: Applying electric current using a TENS device simultaneously with tapping the injection site for 30 to 60 seconds at a rate of about one strike per second, followed by a rapid needle 8 penetration into the skin 2.

A kit for removing an embedded wire from tissue includes a dissector instrument for dissecting tissue surrounding an embedded wire and a pulling instrument for pulling the embedded wire from the tissue. The dissector instrument includes a proximal portion with a first and second handle and a distal portion. The distal portion of the dissector instrument includes a tubular section for surrounding an embedded wire. The pulling instrument includes a proximal portion with a first and second handle and a distal portion. The distal portion of the pulling instrument includes an elongated clamp for coupling to the embedded wire for extraction. The dissector instrument and pulling instrument may be used together as a kit, or separately to extract embedded wire from tissue.

Systems, devices and methods are disclosed related to shapeable lead assemblies. Such lead assemblies can be configured to be shaped in a desired manner before and/or during a procedure, such as, for example, after the lead assembly has been at least partially placed within the anatomy of a subject. The shapeable lead assembly can be shaped during a neuroregenerative procedure to contact and/or otherwise interface with a targeted nerve.

An acupuncture stimulation system comprises a skin overlaying component and a strap having hook-and-loop fastener material, the strap can be wrapped around the skin overlaying component to snugly secure a portion of the system. The skin overlaying component includes: a first electromagnetic form for providing electromagnetic stimulation to a first acupuncture point “Spleen 10”, a second electromagnetic form for providing electromagnetic stimulation to a second acupuncture point “Heting (S 156)”, a third electromagnetic form for providing electromagnetic stimulation to a third acupuncture point “Stomach 34”, a fourth electromagnetic form for providing electromagnetic stimulation to a fourth acupuncture point “Hsiyen (S 145)”, a fifth electromagnetic form for providing electromagnetic stimulation to a fifth acupuncture point “Stomach 35”, and a sixth electromagnetic form for providing electromagnetic stimulation to a sixth acupuncture point “Bladder 40”, to achieve analgesia, cartilage repair and regeneration in the knee joint.

Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a subject. The present disclosure comprises apparatus for the controlled administration of the therapeutic agent through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.

In certain variations, systems and/or methods for electromagnetic induction therapy are provided. One or more ergonomic or body contoured applicators may be included. The applicators include one or more conductive coils configured to generate an electromagnetic or magnetic field focused on a target nerve, muscle or other body tissues positioned in proximity to the coil. One or more sensors may be utilized to detect stimulation and to provide feedback about the efficacy of the applied electromagnetic induction therapy. A controller may be adjustable to vary a current through a coil to adjust the magnetic field focused upon the target nerve, muscle or other body tissues based on the feedback provide by a sensor or by a patient. In certain systems or methods, pulsed magnetic fields may be intermittently applied to a target nerve, muscle or tissue without causing habituation.

Systems and methods for providing a trial neurostimulation to a patient for assessing suitability of a permanently implanted neurostimulation are provided herein. In one aspect, a trial neurostimulation system includes an EPG affixation device that secures the EPG to the patient when connected to a lead extending through a percutaneous incision to a target tissue location, while allowing for ready removal of the EPG for charging or bathing. In another aspect, the system includes an EPG provided with a multi-purpose connector rectacle through which the EPG can deliver neurostimulation therapy to an implanted lead or the EPG can be charged. In yet another aspect, the EPG can include a multi-purpose connector receptacle that is alternatingly connectable with a plurality of differing connector to facilitate differing types of therapies with one or more neurostimulation devices, ground patches or various other devices, such as charging or testing devices.

It has been discovered that pain felt in a given region of the body can be treated by stimulating a peripheral nerve at a therapeutically effective distance from the region where pain is felt to generate a comfortable sensation (i.e., paresthesia) overlapping the regions of pain. A method has been developed to reduce pain in a painful region following limb joint replacement by stimulating a peripheral nerve innervating the painful region with an electrode inserted into tissue and spaced from the peripheral nerve. This method may be used to help alleviate postoperative pain in patients following total knee arthroplasty surgery or other limb joint replacement surgeries.

Disclosed is a skin treatment needle by which energy is supplied into skin tissue to increase the speed of skin regeneration. The skin treatment needle includes a needle body that is formed of a conductive material and inserted into skin, starting from a front end thereof. A region of an outer circumferential surface of the needle body includes a conductive portion which is a region inducing an electric field different from those formed at other portions of the needle body, and the conductive portion includes a plurality of corrugations to cause an electric field formed via the conductive portion to have a uniform distribution without being biased and concentrated to a side.