A catheter system comprises an elongate catheter body including a distal end, a cannulation lumen extending through the catheter body and terminating at the distal end of the catheter body, and a steering element extending through the catheter body for steering the distal end. The catheter system also comprises an imaging element secured to a distal end portion of the catheter body and configured to obtain optical images of an area located distally of the distal end of the catheter body. The catheter body includes a ridge extending axially along an outer surface of the distal end portion, wherein a width of the ridge measured about a circumference of the catheter body is less than a length of the ridge measured along the longitudinal axis, and the imaging element is radially aligned with the ridge with at least a portion of the imaging element disposed within the ridge.

Systems and methods for treating congestive heart failure with high frequency stimulation are disclosed. A representative method for treating a patient includes applying an electrical signal having a frequency of from about 1 kHz to about 100 kHz to the patient via a treatment system that includes a signal delivery element in electrical communication with the patient's vagus nerve at a portion of the vagus nerve located at or proximate to the anterior interventricular junction of the patient's heart. The method can further include automatically detecting at least one physiological parameter of the patient, automatically determining at least one of an ejection fraction of the patient's heart and a correlate of the ejection fraction based on the detected parameter, and automatically adjusting the applied signal based on the determined ejection fraction.

In some examples, a computing apparatus may determine information corresponding to a data structure and indicating delays associated with an atrium lead, a left ventricle (LV) lead, and a right ventricle (RV) lead based on one or more input variables. The computing apparatus may determine a plurality of individualized characteristics based on the information corresponding to the data structure. The computing apparatus may receive, from the plurality of measurement electrodes, a plurality of second sets of electrical measurements indicating second electrical signals applied to the patient's heart based on the plurality of individualized characteristics. The computing apparatus may determine cardiac resynchronization index (CRI) values using a first set of electrical measurements (e.g., native measurements) and the plurality of second sets of electrical measurements. The computing apparatus may generate a graphical representation based on a populated data structure and cause display of the graphical representation.

Various embodiments of an implantable medical device and a system that includes such device are disclosed. The device includes a housing that includes a polymeric material, a sealed container disposed within the housing, and an electronic assembly disposed within the container. The device also includes a battery disposed within the container and electrically connected to the electronic assembly.

A leadless cardiac pacemaker device is configured to provide HIS bundle pacing and contains a housing having a tip, a first electrode arranged on the housing in the vicinity of the tip, the first electrode being configured to engage with intra-cardiac tissue, and a second electrode arranged on the housing at a distance from the tip of the housing. A processor is enclosed in the housing and operatively connected to the first electrode and the second electrode. The processor is configured to process a reception signal received by at least one of the first electrode and the second electrode and to generate a pacing signal to be emitted using at least one of the first electrode and the second electrode.

An implant tool system includes an implantable medical lead and a delivery catheter. The implantable medical lead is configured to be delivered through an access point on a body of a patient. The delivery catheter is configured to deliver the implantable medical lead along an implantation path in the body of the patient. A visual marker is positioned on a body of the implantable medical lead. The visual marker is positioned proximal a distal end of the implantable medical lead by a distance indicative of a length of lead to introduce into the body of the patient. The visual marker may be positioned such that introduction of the length of lead into the body of the patient provides lead slack that reduces the likelihood of one or more of dislodgment of the implantable medical lead from the implant point or damage to a tissue of the patient.

In some examples, a method comprises sensing one or more left-ventricular activations via one or more electrodes of a left-ventricular lead, wherein each of the one or more left-ventricular activations are in response to delivery of an electrical stimulation to a heart of a patient; determining one or more left-ventricular activation metrics based on the sensed one or more left-ventricular activations; and determining whether the electrical stimulation provided conduction system pacing based on the one or more ventricular activation metrics.

Improvements to intracardiac devices such as intracardiac blood pump assemblies, and associated methods. In one example, the present technology includes systems and methods for pacing the heart, and/or performing cardiac ablation using electrodes mounted on a portion of the intracardiac device. In another example, the present technology includes systems and methods for detecting mural thrombi in a patient's heart using electrical sensors or ultrasonic phased arrays mounted on the intracardiac device. In another example, the present technology includes systems and methods for detecting tissue changes and reactions in heart tissue during treatment using one or more temperature sensors. In another example, the present technology includes an improved distal tip for use with an intracardiac device. In another example, the present technology includes systems and methods for maintaining an intracardiac device in a desired position within a patient's heart using magnets or ultrasonic phased arrays mounted on the intracardiac device.

A partially-masked electrode includes a conductive material and an insulated coating having an outer surface. The insulated coating defines a contoured opening that exposes or reveals an area of the conductive material, wherein the contoured opening has an upper perimeter at the outer surface of the insulated coating. When the upper perimeter of the insulated surface coating is placed in contact with a tissue of interest, wherein the tissue of interest is proximate a blood pool, the insulated coating creates a seal between the blood pool and the contoured opening so that no blood in the blood pool can contact the conductive material. This seal reduces or eliminates the reception of far field effects in the blood pool by the electrode, making it easier to locate and diagnose unhealthy tissue.

The present invention relates to an electrode assembly system for treatment of internal organ oedema by electro-osmosis and/or electrophoresis by delivering an electric field, the system comprising a first electrode, a second electrode, and a control unit, wherein the first electrode and second electrode are electrically connected to the control unit, the control unit being adapted to charge the first electrode negatively and the second electrode positively, and to directly control a strength of an electric field induced by the first electrode and the second electrode to a preset value for generating a treatment-specific electric flux. The present invention also relates to the use of such system, as well as a process of treatment of internal organ oedema using such system.