Systems and methods are disclosed to stimulate tissue to treat medical conditions involving tissues such as the bone, spine, stomach, nerves, brain and the cochlea. The disclosed invention uses electrical stimulation of the tissue, where vibrational (or acoustic) energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined tissue sites. The vibrational energy is generated by a controller-transmitter, which could be either implanted or located externally. The vibrational energy is received by a receiver-stimulator, which could be located at or close to the stimulation site.

A device for performing electrotherapeutic massage on the human head, neck, and shoulders includes an inner core structure, at least four protruding nodules, plural electrical wires, and an outer covering. The inner core structure has a central horizontal accommodating opening for accommodating the neck and plural horizontal cushion openings. The horizontal accommodating opening matches the curvature and alignment of the human cervical spine and the kyphotic curvature of the thoracic vertebrae. Each protruding nodule is made of an electrically conductive fabric and sewn to the wall of the corresponding horizontal cushion opening in order to deliver the electrical nerve stimulation pulses generated by an electrotherapeutic signal generator to the corresponding body portion, thereby relaxing the nerve and muscle groups therein. The electrical wires electrically connect the protruding nodules to the electrotherapeutic signal generator. The outer covering encloses the inner core structure while exposing the protruding nodules.

An implantable pulse generator (IPG) is disclosed having a plurality of electrode nodes, each electrode node configured to be coupled to an electrode to provide stimulation pulses to a patient's tissue. The IPG includes a digital-to-analog converter configured to amplify a reference current to a first current specified by first control signals; a first resistance configured to receive the first current, wherein a voltage across the first resistance is held to a reference voltage at a first node; a plurality of branches each comprising a second resistance and configured to produce a branch current, wherein a voltage across each second resistance is held to the reference voltage at second nodes; and a switch matrix configurable to selectively couple any branch current to any of the electrode nodes via the second nodes.

The present invention concerns a method for treating osteoarthritis and/or one of its symptoms in a human or animal subject, which comprises the application of a portable device for transmitting electromagnetic waves to said human or animal subject, wherein said portable device is capable, when it is affixed at a surface, of transmitting waves having a power flux density of at least 0.5 mW/cm.sup.2 of surface and a frequency value of between 3 and 120 gigaHertz (GHz), the device being further capable of simultaneously exposing at least 2.5 cm.sup.2 of the surface to the waves.

An implantable pulse generator (IPG) is disclosed having a plurality of electrode nodes, each electrode node configured to be coupled to an electrode to provide stimulation pulses to a patient's tissue. The IPG includes a digital-to-analog converter configured to amplify a reference current to a first current specified by first control signals; a first resistance configured to receive the first current, wherein a voltage across the first resistance is held to a reference voltage at a first node; a plurality of branches each comprising a second resistance and configured to produce a branch current, wherein a voltage across each second resistance is held to the reference voltage at second nodes; and a switch matrix configurable to selectively couple any branch current to any of the electrode nodes via the second nodes.

A method includes receiving monitoring data from at least one sensing device coupled to a subject and analyzing the monitoring data to identify one or more physiologic parameters of the subject. The method also includes providing signaling to at least one stimulating device in response to the identified physiologic parameters, the signaling comprising instructions to apply a stimulus to the subject. The method further includes receiving additional monitoring data from the at least one sensing device, analyzing the additional monitoring data to identify one or more changes in the one or more physiologic parameters of the subject after application of the stimulus to the subject, and providing additional signaling to the at least one stimulating device, the additional signaling comprising instructions to modify the stimulus applied to the subject based on the identified changes in the one or more physiologic parameters.

A method includes receiving monitoring data from at least one sensing device coupled to a subject and analyzing the monitoring data to identify one or more physiologic parameters of the subject. The method also includes providing signaling to at least one stimulating device in response to the identified physiologic parameters, the signaling comprising instructions to apply a stimulus to the subject. The method further includes receiving additional monitoring data from the at least one sensing device, analyzing the additional monitoring data to identify one or more changes in the one or more physiologic parameters of the subject after application of the stimulus to the subject, and providing additional signaling to the at least one stimulating device, the additional signaling comprising instructions to modify the stimulus applied to the subject based on the identified changes in the one or more physiologic parameters.

Devices, systems, and techniques for calibrating posture state definitions are described. In one example, a system includes a memory configured to store a plurality of posture state definitions defining a plurality of posture states. The system may also include processing circuitry configured to receive a request to update the plurality of posture state definitions, responsive to receiving the request, and obtain sensor data for one posture state of the plurality of posture states, wherein the sensor data generated while a patient is in the one posture state. The processing circuitry may also determine a difference between the sensor data and a posture state definition of the posture state definitions corresponding to the one posture state, update, based on the difference, the plurality of posture state definitions, and store the updated plurality of posture state definitions in the memory.