An optical stimulation system includes a light source configured to produce light for optical stimulation; a light monitor; an optical lead coupled, or coupleable, to the light source and the light monitor; and a control module coupled, or coupleable, to the light source and the light monitor. The control module includes a memory, and a processor coupled to the memory and configured for receiving a request for verification or measurement of a light output value; in response to the request, receiving, from the light monitor, a measurement of light generated by the light source; and, based on the measurement, reporting a response to the request.

A wireless power transfer system that employs a form of conductively coupled power transfer to transfer energy to deeply implanted devices.

A method includes receiving, with one or more processors, a first ambulatory velocity information of a patient while electrical stimulation with a first set of stimulation parameters is being delivered to the patient; adjusting, based on the first ambulatory velocity information and by a predetermined amount, one or more of the first set of stimulation parameters to generate an adjusted set of stimulation parameters by a predetermined amount; receiving, with the one or more processors, a subsequent ambulatory velocity information of the patient while the electrical stimulation with an adjusted set of stimulation parameters is being delivered to the patient; and generating, with the one or more processors and based on the subsequent ambulatory velocity, one or more recommended electrical stimulation parameters the patient.

A system includes at least one medical device (7), a remote monitoring server (RMS, 1) and at least one patient remote device (PR, 5). The the PR is configured to establish a first bidirectional communication connection (12, 14) of the PR and the RMS and a second bidirectional communication connection (13, 14) of the PR and one chosen medical device, wherein the PR is further configured to manage remote processes associated with the chosen medical device comprising remote interrogation of the chosen medical device and remote programming of the chosen medical device using the second bidirectional communication connection as well as data exchange with the RMS concerning interrogation data and/or program data with regard to the chosen medical device using the first bidirectional communication connection.

An electrical stimulation system includes at least one electrical stimulation lead having stimulation electrodes; and a processor coupled to the at least one electrical stimulation lead to perform actions, including: directing delivery of at least one stimulation pulse to tissue of a patient during each charge injection phase, where each consecutive pair of the charge injection phases is separated by a charge recovery phase; and, for at least one stimulation pulse: during delivery of the stimulation pulse, directing application of at least one charge recovery pulse to interrupt the delivery of the stimulation pulse, where each one of the at least one charge recovery pulse has a relative amplitude that is larger in magnitude than an amplitude of the stimulation pulse; and, after application of the charge recovery pulse, directing resumption of delivery of the stimulation pulse at the amplitude of the stimulation pulse.

An example of a system for delivering neurostimulation may include a programming control circuit and a stimulation control circuit. The programming control circuit may be configured to generate stimulation parameters controlling delivery of the neurostimulation according to a stimulation configuration. The stimulation control circuit may be configured to specify the stimulation configuration, and may include volume definition circuitry and stimulation configuration circuitry. The volume definition circuitry may be configured to determine one or more test volumes, determine a clinical effect resulting from the one or more test volumes each being activated by the neurostimulation, and determine a target volume using the determined clinical effect. The stimulation configuration circuitry may be configured to generate the specified stimulation configuration for activating the target volume.

A prosthetic device includes a closed loop system for maintaining a predetermined concentration of a target ion in a region in proximity to a cell, such as a nerve cell. The device includes a controller and an ion-selective electrode assembly operatively connected to the controller, wherein the ion-selective electrode configuration is configured to sense the concentration of the target ion by potentiometric measurement and to convey the concentration to the controller. The controller is configured to modulate the current to the ion-selective electrode assembly based on the concentration of the target ion to control the concentration of the target ion so as to maintain the predetermined concentration of the target ion.

The invention provides systems and methods for monitoring electrical biosignals of one or more biological cells, tissues, and/or organs of a patient and assessing a condition of the patient based on the electrical biosignals.

An implantable medical device comprising a sealed flat housing enclosing an electronic circuitry; a plurality of feedthrough conductors, each feedthrough conductor comprising a proximal end part connected to the enclosed electronic circuitry and a distal end part extending from a side surface of the housing and cumulated on said side surface; a tubing that houses a plurality of wires connected to said feedthrough conductors and that is arranged on the housing; and a longitudinal slit through the wall of the tubing through which the wires extend out of the tubing.

An electrical stimulation lead includes a cuff having a cuff body having an exterior surface, an interior surface, and a circumference; longitudinally elongated electrodes disposed on the interior surface of the cuff body and helically arranged with each of the longitudinally elongated electrodes longitudinally offset relative to any adjacent longitudinally elongated electrodes; and a longitudinal slit extending through the cuff body and further extending along an entire length of the cuff body, the longitudinal slit operable to receive a portion of a target nerve from a region outside of the cuff to within the cuff body. The lead also includes a lead body coupled to the cuff and conductors extending through the lead body and the cuff with the conductors electrically coupled to the longitudinally elongated electrodes.