Methods, implantable devices, and systems for treating a cancer or inhibiting cancer growth or recurrence in a subject are described herein. Such methods can include electrically stimulating a thoracic splanchnic nerve (such as a greater splanchnic nerve) of the subject with a plurality of electrical pulses emitted from one or more electrodes m electrical communication with the splanchnic nerve, wherein the plurality of electrical pulses triggers one or more action potentials in the splanchnic nerve to increase circulating natural killer (NK) cells in the subject. An implantable device may include one or more electrodes configured to be in electrical communication with a thoracic splanchnic nerve of a subject with cancer, and be configured to operate the one or more electrodes to electrically stimulate the splanchnic nerve with a plurality of electrical pulses that triggers one or more action potentials in the splanchnic nerve that increase circulating NK cells.

Examples disclosed herein are relevant to selectively bypassing a verification stage in controlling a device based on a received command. Verification can be bypassed when certain conditions are met, such as the occurrence of one or more scenarios. Disclosed techniques can be applied to any of a variety of devices, such as those that use a verification stage in addition to a command stage.

Examples disclosed herein are relevant to selectively bypassing a verification stage in controlling a device based on a received command. Verification can be bypassed when certain conditions are met, such as the occurrence of one or more scenarios. Disclosed techniques can be applied to any of a variety of devices, such as those that use a verification stage in addition to a command stage.

An apparatus includes a body configured to be at least partially implanted on or within a recipient and a plurality of electrodes positioned along the body. The plurality of electrodes includes a first set of electrodes configured to apply electrical stimulation signals to at least a portion of the recipient. The plurality of electrodes further includes a second set of electrodes configured to apply an electric field to cell membranes of the recipient, the electric field configured to increase a permeability of the cell membranes to a substance.

The embodiments described herein relate to a self-positioning, quick-deployment low profile transvenous electrode system for sequentially pacing both the atrium and ventricle of the heart in the “dual chamber” mode, and methods for deploying the same.

An apparatus is provided for remotely powering an implantable medical device (IMD) positioned at a target treatment location within a patient. The apparatus is configured to be positioned at or near an external skin surface of the patient in proximity to the target treatment location. The apparatus includes an induction coil which, when placed in proximity to the IMD, forms an inductive transcutaneous power link with the IMD such that when the induction coil is supplied with a current, the induction coil inductively and transcutaneously delivers power to the IMD. An aerogel layer is disposed between the induction coil and the patient's skin surface. The aerogel layer is configured to receive heat generated from the induction coil and regulate heat dissipation from the aerogel layer to minimize heat transfer to the patient.

Cochlear implant systems can include a cochlear electrode and a stimulator in electrical communication with the cochlear electrode. The stimulator can be in communication with a controller, which is in communication with a testing circuit and a switching network. The stimulator can include a plurality of source elements. The controller can control the switching network to place the plurality of source elements into communication with the testing circuit. The controller can further cause one of the plurality of source elements to emit an electrical current and can determine an amount of electrical current emitted from the source element using the testing circuit. The controller can compare the determined amount of electrical current emitted by the source element with a prescribed current. The controller can adjust the output of each of the plurality of source elements based on the determined amount of electrical current emitted by the stimulator.

A stimulation system for delivery of a stimulation signal to a hypoglossal nerve of a patient to treat obstructive sleep apnea. The stimulation system includes an implantable receiver coil configured to be implanted under a mandible of the patient; a nerve electrode coupled to the implantable receiver coil, the nerve electrode configured to deliver the stimulation signal to the hypoglossal nerve of the patient; an external pulse generator configured to generate the stimulation signal; and an external transmitter coil configured to wirelessly transmit the stimulation signal from the external pulse generator to the implantable receiver coil, the external transmitter coil being carried by an adhesive patch configured to be placed on the skin adjacent the implantable receiver coil under the mandible of the patient.

A trial stimulation system includes a trial electrical stimulator. Additionally, systems for securing a disposable trial stimulator to the body of a patient are described, which may function to improve the durability of the system during the trial period and reduce the risk of damage or malfunction to the system due to lead/electrode dislocation and/or off-label uses like showering or bathing with the trial stimulator still secured to the body.

An example of a system may include a processor, and a memory device comprising instructions, which when executed by the processor, cause the processor to access at least one of patient input, clinician input, or automatic input, use the patient input, clinician input, or automatic input in a search method, the search method designed to evaluate a plurality of candidate neuromodulation parameter sets to identify an optimal neuromodulation parameter set, and program a neuromodulator using the optimal neuromodulation parameter set to stimulate a patient.