A light irradiating medical device 1 includes a catheter shaft 2 extending in a longitudinal direction; a balloon 5 disposed at a distal portion of the catheter shaft 2; a light guiding tool 10 disposed in a lumen of the catheter shaft 2 and movable in the longitudinal direction, the light guiding tool 10 including an optical fiber 11 extending in the longitudinal direction and a tubular member 15 covering the optical fiber 11 and having light transparency, the optical fiber 11 including a core 12, a cladding 13 and a cladding absent portion 14 disposed at a part of a distal portion of the core 12; a first radiopaque marker 21 disposed at the distal portion of the catheter shaft 2; and a second radiopaque marker 22 disposed at the tubular member 15 at a position distal to a distal end 12a of the core 12.

A process that provides protective therapy for biological tissues or fluids includes applying a pulsed energy source to a target tissue or a target fluid having a chronic progressive disease or a risk of having a chronic progressive disease to therapeutically or prophylactically treat the target tissue or target fluid. The pulsed energy source has energy parameters selected so as to raise the target tissue or bodily target fluid temperature up to a predetermined temperature for a short period of time to achieve a therapeutic or prophylactic effect, while the average temperature rise of the target tissue or target fluid over a longer period of time is maintained at or below a predetermined level so as not to permanently damage the target tissue or target fluid.

A process for preventing or treating myopia includes applying a pulsed energy, such as a pulsed laser beam, to tissue of an eye having myopia or a risk of having myopia. The source of pulsed energy has energy parameters including wavelength or frequency, duty cycle and pulse train duration, which are selected so as to raise an eye tissue temperature up to eleven degrees Celsius to achieve therapeutic or prophylactic effect, such as stimulating heat shock protein activation in the eye tissue. The average temperature rise of the eye tissue over several minutes is maintained at or below a predetermined level so as not to permanently damage the eye tissue.

A treatment method and a treatment system for irradiating the antibody-photosensitive substance bound to the tumor cell membrane in the tumor cell with the near-infrared ray includes: intravenously administering the antibody-photosensitive substance; inserting an endoscope from a mouth, a nose, or an anal and allowing the endoscope to reach a vicinity of a tumor; making a tubular elongated tube, in which a lumen is formed, protrude from the endoscope; bringing the elongated tube into contact with the tumor while checking an image obtained by the endoscope; allowing an optical fiber inserted into the lumen of the elongated tube to reach an inside or the vicinity of the tumor; and irradiating the antibody-photosensitive substance bound to the tumor cell membrane with the near-infrared ray from the optical fiber after 12 hours to 36 hours from the intravenous administration.

A treatment method and a treatment system capable of effectively irradiating an antibody-photosensitive substance bound to a tumor cell with a near-infrared ray. The treatment method for irradiating the antibody-photosensitive substance bound to the tumor cell membrane in the tumor cell with the near-infrared ray includes: intravenously administering the antibody-photosensitive substance; percutaneously puncturing a tumor or a vicinity of the tumor with a hollow outer needle, while percutaneously acquiring and checking an ultrasound image; making an inner needle having a plurality of sharp inner needle tips protrude from the outer needle, and puncturing the tumor or the vicinity of the tumor with the inner needle tips; and irradiating the antibody-photosensitive substance bound to the tumor cell membrane with the near-infrared ray from an optical fiber inserted into the inner needle after 12 hours to 36 hours from the intravenous administration.

Low-level light therapy (LLLT) can be applied to a subject suffering from gut dysbiosis in order to restore the subject's gut microbiota to a state of heath. A subject can be placed proximal to a light source device. The light source device can be configured to apply LLL with wavelengths from the red to infrared part of the spectrum. The LLL can be applied at a power density and for a time sufficient to restore the subjects gut microbiota to a state of health.

Systems and methods are provided for performing a treatment of a lesion within a subject using an endoscopic device. The endoscopic device comprises an endoscope and a catheter. The endoscope is configured to be inserted into the subject and includes a working channel. The catheter is configured to pass through the working channel of the endoscope. The catheter further comprises a sheath, an expandable device, and a light source. The sheath has a lumen and the expandable device may include an inflatable balloon. The light source is configured to be controllable through the lumen of the sheath. The light source is configured to selectively apply light to the lesion within the subject when the endoscope is inserted into the subject.

An ingestible capsule arranged, in use, to cross a human stomach for carrying out a phototherapeutic treatment arranged to combat an infection due to the presence of the bacterium Helicobacter pylori, the ingestible capsule comprising at least one primary light source arranged to emit an electromagnetic phototherapeutic wave having a wavelength λ.sub.1, at least one auxiliary light source arranged to emit an electromagnetic phototherapeutic wave having a wavelength λ.sub.2, a wrapper arranged to contain the or each primary light source and the or each auxiliary light source, the wrapper being at least partially transparent to the wavelengths λ.sub.1, and λ.sub.2, a control unit arranged to selectively activate the or each primary light source and/or the or each auxiliary light source.

The present invention is directed to a method for treating a bowel disease in a subject in need thereof, the method comprising inhibiting the activity of neurons of the insular cortex of the subject. Further provided is a system comprising a transcranial stimulation transducing coil for transcranial stimulation configured to provide a series of pulses to neurons of the insular cortex.

Systems and method relate to administering phototherapy. A device includes a hollow structure having at least a first open end. The hollow structure includes a rotatable member, one or more coherent light generators, and, for each coherent light generator, one or more lenses or mirrors optically connected to the coherent light generator and configured to alter at least one aspect of a beam of coherent light. The device further includes a processing circuit including a processor and a memory storing instructions. The instructions, when executed by the processor, cause the processor to accept an input from an operator and generate one or more beams of coherent light according to a plurality of settings configured to produce a therapeutic effect at a targeted treatment site. Additionally, the rotatable member is configured to be rotated to direct the one or more beams of coherent light to the targeted treatment site.