A stimulation device includes an energy source; an electronics unit; an actuator that is coupled with the electronics unit and/or the energy source. The electronics unit includes a controller. The energy source, the electronics unit and the actuator are arranged in a housing. A fixing unit which is coupled with the housing and affixes the stimulation device on a heart or in a heart. The actuator emits electromagnetic waves for the stimulation of genetically manipulated tissue, and the controller controls the stimulation of the tissue by way of the electromagnetic waves of the actuator.

A therapeutic light delivery apparatus and method are disclosed. The apparatus includes a light source, a plurality of light emitting devices paired with a plurality of light detecting devices, wherein each of the light emitting devices is in optical communication with a channel of a delivery optical switch and each of the plurality of light detection devices is in optical communication with a channel of a detection optical switch. The plurality of light emitting devices are fixedly positioned within an applicator light flap. The system further includes an optical detector in optical communication with the detector optical switch. The system further includes an opto-electronic controller that controls delivery optical switch, the detector optical switch and the light source.

At least one pulsed light beam is applied to eye tissue to raise the temperature of the eye tissue to photostimulate the tissue. The at least one light beam has parameters of wavelength, duty cycle, power and pulse train duration selected to achieve a therapeutic or prophylactic effect while not permanently damaging the eye tissue. The eye tissue photostimulation improves ocular health and function and slows or prevents disorders associated with a normally aging eye.

Systems and methods are described for treatment of neurological conditions in which transcranial illumination using infrared, near-infrared and/or red wavelengths of light are delivered into the brain of a patient using a portable head wearable device. Arrays of light emitters are simultaneously controlled to provide a selected power density and distribution during a therapeutic session to treat a condition of the patient. An external controller such as a touchscreen tablet or laptop computer can be used to select illumination parameters for each patient. The system can be used to provide treatment to children such as those having autism spectrum disorder (ASD).

An optical stimulation system includes a light source configured to produce light for optical stimulation; a light monitor; an optical lead coupled, or coupleable, to the light source and the light monitor; and a control module coupled, or coupleable, to the light source and the light monitor. The control module includes a memory, and a processor coupled to the memory and configured for receiving a request for verification or measurement of a light output value; in response to the request, receiving, from the light monitor, a measurement of light generated by the light source; and, based on the measurement, reporting a response to the request.

A light therapy system is made up of a pressure cuff system having a cuff that is positionable on or near a body part of a user and that can receive pressurized air to selectively pressurize and depressurize the cuff and a light emitting system having a supporting structure and a light emitter positioned on the supporting structure, the light emitter being controllably powerable. The supporting structure is positionable on an interior surface of the cuff so that the light emitter can direct light onto the body part. The light therapy system can further include a controller capable of controllably powering the light emitter, wherein controller can adjust the intensity or duration of the light directed onto the body part in response to an input or measurement related to a condition of the body part. A photometer can be provided separately or integrally to measure the condition of the body part. A method of providing light therapy is also provided.

A phototherapy method comprising: irradiating an affected area that is administered with a phototherapeutic agent with therapeutic light in a first period; and irradiating the affected area with the therapeutic light in a second period after the first period, wherein the second period is a period after the intensity of a first light that is emitted from the phototherapeutic agent has significantly decreased by irradiation with the therapeutic light in the first period, and an irradiation energy dose of the therapeutic light in the second period is determined based on a state of the affected area.

The present disclosure relates to systems, methods, and uses of systems for treating a skin condition with phototherapy. A system comprises (a) a phototherapy device comprising a phototherapy light source; (b) a patient computing device comprising a processor and a memory, the patient computing device configured to: transmit a first signal to the phototherapy device enabling operation of the phototherapy device according to one or more conditional prescription parameters, activate the phototherapy light source, and transmit a second signal reporting operation of the phototherapy device; and (c) a server configured to communicate with the patient computing device and receive the second signal. Also disclosed are systems, methods and compositions for controlling phototherapy treatments of the skin comprising (a) incorporating sun exposure into a prescribed phototherapy treatment; (b) quantitative measurement of erythema using digital image processing; (c) computer aided guidance for administration of targeted phototherapy; (d) treatment recommendations from outcome based analytics of a population of connected phototherapy devices; (e) an emollient with UV fading dye to visibly identify treated areas in the administration of targeted phototherapy.

The present disclosure describes a wellness application for digital usage comprising at least one software program that identifies the level of high energy visible light reduction provided by the thin film; and a dosimeter for sending data about ionizing radiation to the software. The software tracks the total time of device usage and determines wherein the software, based on a dosimeter measurement received from the dosimeter, communicates with at least one processor to execute at least one of: determine a notification for reducing exposure to high energy visible blue light about divide user interface, and adjust the display output by at least one of adjusting a color contrast and brightness, taking into account the level of visible light coverage and total time of device usage.

A phototherapy device includes: a treatment light emitter configured to emit treatment light for causing a reaction of a drug; a narrow band light emitter configured to emit narrow band light having part of wavelength band of a visible light range; an excitation light emitter configured to emit excitation light for causing excitation of the drug; a first imager configured to obtain a narrow band light image which is formed using the narrow band light applied onto an application position of the treatment light; a second imager configured to obtain a fluorescence image which is formed using the excitation light emitted onto the application position of the treatment light; and a display image generator configured to generate a superimposed image in which the narrow band light image and the fluorescence image are superimposed.