The invention relates generally to methods of using a thiol-Michael addition hydrogel for providing intracavitary brachytherapy and/or displacing tissue and organs. The thiol-Michael addition hydrogel may be used as a packing material and an attenuation material for intracavitary brachytherapy applications. The invention also relates generally to a brachytherapy applicator, which may be used in conjunction with the thiol-Michael addition hydrogel and methods thereof. The invention also relates to a kit comprising at least one container containing the precursor materials of the thiol-Michael addition hydrogel.

A brachytherapy ring applicator, kit, and method of use is provided. The brachytherapy ring applicatory includes a tandem, ring colpostat, and a bracket assembly. The tandem has a connector on a proximal end of the tandem and a treatment end on a distal end. The ring colpostat includes a ring member on a distal end of the ring colpostat. The bracket assembly is configured to be locked to both a shaft of the tandem and to a shaft of the ring colpostat such that the distal end of the tandem is firmly maintained in a fixed position relative to the distal end of the ring colpostat, and each of the tandem and the colpostat are entirely self-supporting from the bracket assembly to their distal ends.

A design, quality assurance, and clinical use procedures are provided for real-time tracking of a custom MRI/CT-compatible brachytherapy applicators. A real-time tracking system is used for applicator implantation, repositioning and tracking during treatment delivery.

Exemplary applicator(s), devices, systems and methods can be provided for delivering high dose rate radiation therapy, e.g., to patients with cervical cancer. For example, an intrauterine channel can be provided for or with such applicator(s), system(s), device(s) and methods. Further, at least a part of the device should be fixable within the uterus, and be configured and sized to be able to easily inserted and/or removed from the uterus, while be able to easily affix the exemplary device, applicator, etc. in the cavity of the uterus, and hold the channel anchored to the uterus, as it is larger from the cervical canal.

The present invention relates to a body insertable device having an outer body being bent; and an inner body positioned inside the outer body, having an accommodation space in which the resource soured is accommodated, and being capable of rotating inside the outer body, wherein a radiation emission direction is continuously adjusted by rotation of the inner body.

Exemplary brachytherapy applicators may include an interstitial tube having a body with a proximal end and a distal end and a central conduit extending from the distal end of the body, wherein the central conduit includes a proximal opening, a distal opening, and a channel extending from the proximal opening to the distal opening, and wherein the proximal opening is offset from an axis of the body. The proximal opening may be configured to fluidly connect to a brachytherapy guide tube, and the channel of the central conduit may be dimensioned to receive at least one of a needle or a catheter therethrough.

A real-time applicator position monitoring system (RAPS) measures brachytherapy applicator displacement in real-time by computing the relative displacement between two infrared reflective targets, one attached to the applicator and the other to the patient's skin. In an aspect, RAPS can be used with any brachytherapy application. RAPS measures the applicator motion during HDR brachytherapy treatment, as well as during the transfer of the patient from the imaging room (e.g., where the CT and MR scanners are located) to the HDR BT operating/treatment room.

The present application relates to a catheter apparatus including a tubular member, and four or more fluid-flow pipe members, each having a proximal end and a distal end, and each being disposed around a periphery of the tubular member along an axial direction thereof. Each of the four or more fluid-flow pipe members is provided with an independent positioning member at the distal end thereof, and the number of positioning members is four or more. A brachytherapy system and a method of reducing area of radiation exposure of normal tissue in a brachytherapy treatment using the catheter apparatus are also disclosed.

Devices and methods for brachytherapy treatment are disclosed. One aspect is a poly(methyl methacrylate) apparatus for brachytherapy treatment at the vaginal apex. Another aspect is a poly(methyl methacrylate) apparatus for brachytherapy treatment in the distal two-thirds of the vagina. Another aspect is a poly(methyl methacrylate) apparatus for brachytherapy treatment of cancers that are offset from the vaginal apex. Other aspects include methods for guiding needles for treatment of cancers at the vaginal apex, in the distal two-thirds of the vagina, and that are offset from the vaginal apex.

A system includes a device associated with an endoscopy guided procedure including a housing defining a housing channel with at least a portion of the housing configured for deployment within a cavity. The device further includes a plurality of bodies defining respective channels defined within the housing. The housing defines a longitudinal axis, and the plurality of channels extends throughout the housing around the longitudinal axis. Each of the plurality of channels accommodates selective activation of radiation emittance from a predetermined different position along the housing via one or more radiation elements such that the plurality of channels collectively provides a predetermined spatial distribution of a radiation treatment to a target area along the cavity.