A system and method of performing prospective and retrospective on-line adaptive radiotherapy. The method includes performing, during a treatment delivery session, delivery of a dose of radiation to an anatomical volume. The method includes detecting, during the treatment delivery session, a current state of the anatomical volume. The method includes predicting a future change in the current state of the anatomical volume during the treatment delivery session. The method includes adjusting, while the anatomical volume is in the current state, the treatment delivery to anticipate the future change in the anatomical volume.

A system and method of performing prospective and retrospective on-line adaptive radiotherapy. The method includes performing, during a treatment delivery session, delivery of a dose of radiation to an anatomical volume. The method includes detecting, during the treatment delivery session, a current state of the anatomical volume. The method includes predicting a future change in the current state of the anatomical volume during the treatment delivery session. The method includes adjusting, while the anatomical volume is in the current state, the treatment delivery to anticipate the future change in the anatomical volume.

Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.

Systems and methods for shuttle mode radiation delivery are described herein. One method for radiation delivery comprises moving the patient platform through the patient treatment region multiple times during a treatment session. This may be referred to as patient platform or couch shuttling (i.e., couch shuttle mode). Another method for radiation delivery comprises moving the therapeutic radiation source jaw across a range of positions during a treatment session. The jaw may move across the same range of positions multiple times during a treatment session. This may be referred to as jaw shuttling (i.e., jaw shuttle mode). Some methods combine couch shuttle mode and jaw shuttle mode. Methods of dynamic or pipelined normalization are also described.

A system for supporting a brachytherapy treatment includes a medical imaging system and a processing unit. The medical imaging system includes a SPECT unit and/or a CT unit. The processing unit is configured to receive a planning dataset, and determine a brachytherapy treatment plan based on the planning dataset. The treatment plan includes a planned dose distribution for a radiation source. The medical imaging system is configured to acquire a supervision dataset that includes an intra-procedural representation of the radiation source that, in an operating state of the system, has been positioned at a treatment site within a treatment region via a medical guide instrument. The processing unit is configured to register the supervision dataset and the planning dataset, determine an actual dose distribution based on the supervision dataset, and provide supervision information based on a comparison between the planned and actual dose distribution.

This application relates to methods for delivering radiation to a positron-emitting target within a subject under continuous PET guidance. Instead of directing radiation at a collinear path along each detected positron line-of-response (LOR), the methods generally include detecting a pattern of LORs that intersect the target. In response to the pattern, radiation may be delivered along paths that are not necessarily collinear to any of the LORs. Methods for further modifying radiation delivery as well as the detected LOR population are also described.

A boron neutron capture therapy system includes a neutron capture therapy device, a photon emission detection device and a treatment bed. The photon emission detection device includes a detecting portion surrounding the periphery of the treatment bed and detecting gamma rays generated after irradiating a boron-containing drug with neutrons; the detecting portion includes a first detecting portion and a second detecting portion moving away from or close to the first detecting portion so that the detecting portion forms a ring with the radius being increased or decreased; and the ring surrounds the treatment bed. The photon emission detection device for use in the boron neutron capture therapy system can change the radius of the ring, surrounding an irradiated object, of the detecting portion according to the actual condition in the boron neutron capture therapy so as to improve the detection precision of the photon emission detection device.

A method may include obtaining a first acquisition time period related to a scan of a first modality performed on an object. The method may also include obtaining one or more second acquisition time periods related to a scan of a second modality performed on the object. The method may also include obtaining, based on the first acquisition time period and the one or more second acquisition time periods, target data of the object acquired in the scan of the first modality. The method may also include generating one or more target images of the object based on the target data.

Provided is a method for treating a target tissue in a subject by using a particle beam, or further in combination with a reactant. The method includes irradiating the target tissue with the particle beam by scanning under a controlled path in the target tissues.

The disclosure provides a system for EGRT. The system may include a radiotherapy device for treating a subject. The radiotherapy device may include a scintillation camera that is directed at an ROI of the subject. The subject may be injected with a radioactive tracer or implanted with a radioactive marker before treatment. The ROI may undergo a physiological motion during the treatment. The system may deliver a treatment session to the subject by the radiotherapy device. During the treatment session, the system may acquire a target image of the ROI indicative of a distribution of the radioactive tracer or the radioactive maker in the ROI by the scintillation camera, and adapt a radiation beam to be delivered to the subject with respect to the physiological motion of the ROI by adjusting the radiation beam based on the target image.