An image guiding device includes a gantry, an imaging source, an imager, and an image server. The imaging source, the imager and the image server are all mounted on the gantry. The imager is connected to the image server. The imaging source is arranged to face the imager. The imaging source emits X-rays. The imager receives X-rays passing through an affected part of a patient, generates projection data based on the received X-rays, and sends the projection data to the image server. The image server processes the projection data to obtain an image of the affected part.

Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enough information to determine the location of a target region due to, for example, poor or low contrast and/or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images.

A computer based method of obtaining a 3D image of a part of a patient's body is disclosed, based on a fraction image having a limited field-of-view and extending the field of view with information from an image of the patient's outline, obtained from a surface scan of the patient. Anatomical data from the planning image are preferably used to fill in the outline image, by means of a contour-guided deformable registration between the planning image and contour.

A radiotherapy device and a control driving method thereof are provided. The radiotherapy device includes a radiation source apparatus having a plurality of radiation sources, a source carrier and a collimator. The source carrier includes a source box and a source box region conforming to a shape of the source box, the source box is detachably fixed at the source box region, the plurality of radiation sources are mounted in the source box, the source box is provided with a first connecting part, the source carrier is provided with a second connecting part, and the first connecting part is configured to connect the second connecting part.

The invention relates to a system for detecting, obtaining images and treating or eliminating tumours, diseases or other anomalies, which is excited by means of X-rays biomarked with metallic nanoparticles and which comprises an external support structure (600) with a shield, which comprises: a confocal system (1000) comprising a shielded external structure (67, 75) that contains a convergent scan X-ray device (100), a detection system (200) for X-ray photons with collimators that are solidly connected to and confocal with the first device, a second convergent treatment device (300) solidly connected to the confocal structure (100 and 200), and a supporting structure (400) that contains the convergent scan X-ray device (100), the detection system (200) and the second convergent treatment device (300), which project to a single focal point, and which ensures that same are confocal; a controlled 3D scanning structure (500) that moves a bed and/or focal point onto which ionising radiation is concentrated; an electronic control system comprising programmable electronics (700) that allow the operation of the convergent beam device, the operation of the sensors (2) and the movements of the 3D scanning system; and a computed tomography (CT) device (2000) comprising collimators, an X-ray tube and sensors and which is incorporated into the structure (600). The invention further relates to an associated method.

A system and method for delivering microbeam radiation therapy (MRT) includes a computed tomography scanner (“CT”) configured to generate tomographic images of a subject, or patient, the scanner including an imaging apparatus, a gantry with an opening for positioning the patient therein, an axis of rotation around which the gantry rotates, and an x-ray source mounted to and rotatable with the gantry. The system includes a bed for patient positioning within the gantry opening and a multi-slit collimator removably mounted downstream of the x-ray source for delivering an array of microbeams of MRT to a targeted portion of the patient. Switching between MRT and CT is provided, and MRT modes of operation include a stationary mode, and continuous and step-wise rotational modes.

A tumor positioning method includes obtaining projection images of a tumor at different angles; and registering the projection images with an initial reference image to obtain a first offset. If it is determined that a virtual reacquisition operation needs to be performed according to the first offset, the method further includes generating a first reference image according to the first offset; and registering the projection images with the first reference image to obtain a second offset. If it is determined that the operation does not need to be performed according to the second offset, the method further includes outputting a first accumulated offset being a sum of the first and second offsets. The method may solve problems of long time consuming and the service life of a treatment couch and acquisition devices being reduced due to repeatedly moving the treatment couch and repeatedly acquiring the X-ray projection images.

The present invention makes it possible to provide a radiation therapy system capable of not only inhibiting treatment time from increasing more effectively than before but also reducing the loads of fluoroscopic radiation photographing apparatuses. The radiation therapy system has: a therapeutic radiation irradiation apparatus to irradiate a target with therapeutic radiation; two fluoroscopic radiation photographing apparatuses to photograph the target simultaneously from two directions; a target position computation apparatus to compute a three-dimensional position of the target on the basis of photographed fluoroscopic images; a therapeutic radiation irradiation control apparatus to control the irradiation of the therapeutic radiation on the basis of the computed three-dimensional position of the target; and a fluoroscopic radiation photographing control apparatus to control irradiation quantities per unit time of the fluoroscopic radiation photographing apparatuses on the basis of the three-dimensional position of the target.

The present invention relates to a radiotherapy apparatus and a method for determining target positions using a radiotherapy apparatus, so as to accurately detect the motion of the tumor position. The method includes: a ray source locating in a first position, and emitting a radiation beam; a detector receiving the radiation beam emitted by the ray source at the first position, and generating first image data of the target according to the radiation beam emitted by the ray source at the first position; the ray source moving to a second position and emitting a radiation beam, wherein an interval at which the ray source moves from the first position to the second position is a positive integer multiple of a preset breathing cycle of a patient; the detector receiving the radiation beam emitted by the ray source at the second position, and generating second image data of the target according to the radiation beam emitted by the ray source at the second position; and determining position information of the target according to the first image data and the second image data.

Systems and methods are provided for registering images. The systems and methods perform operations comprising: receiving, at a first time point in a given radiation session, a first imaging slice corresponding to a first plane; encoding the first imaging slice to a lower dimensional representation; applying a trained machine learning model to the encoded first imaging slice to estimate an encoded version of a second imaging slice corresponding to a second plane at the first time point to provide a pair of imaging slices for the first time point; simultaneously spatially registering the pair of imaging slices to a volumetric image, received prior to the given radiation session, comprising a time-varying object to calculate displacement of the object; and generating an updated therapy protocol to control delivery of a therapy beam based on the calculated displacement of the object.