A computer-implemented method of performing a treatment fraction of radiation therapy comprises: determining a current position of a target volume of patient anatomy; based on the current position of the target volume, computing an accumulated dose for non-target tissue proximate the target volume; determining that the accumulated dose is less than a current value for a dose budget of the non-target tissue; and in response to the accumulated dose being less than the current value for the dose budget, applying a treatment beam to the target volume while the target volume is in the current position.

A radiotherapy device, a method and a computer readable medium are disclosed. The radiotherapy device includes a radiation source and a controller. The radiation source is configured to apply radiation to a subject. The controller is configured to determine an overlap between a defined volume of the subject and an isodose surface and to instruct the radiation source to halt application of the radiation based on the determination.

Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.

A method of and apparatus for operating a radiation treatment delivery system. The method includes generating, by a processing device, a set of instructions for a volumetric imager based on a set of directionalities for a radiation beam of a linear accelerator (LINAC) to avoid a collision between the volumetric imager and the LINAC, wherein the set of instructions comprises physical locations of the volumetric imager and timing values corresponding to the physical locations. The method further includes operating the volumetric imager during the radiation treatment delivery according to the set of instructions.

There is disclosed a method for estimating the position of a target in a body of a subject. The method includes, receiving an external signal that is related with motion of the target; and using a model of a correlation between the external signal and the motion of the target to estimate the position of the target, wherein said position estimation includes an estimate of three dimensional location and orientation of the target. The method further includes periodically receiving a 2-dimensional projection of the target; and updating the model of correlation between the external signal and the motion of the target based on a comparison of the estimated position of the target and the 2-dimensional projection of the target. The method is used in guided radiation therapy.

Systems and methods are provided for single isocenter radiotherapy of multiple targets. Conformal arc information may be used in a Conformal Arc Informed Volumetric Modulated Arc Therapy (CAVMAT) method that includes single isocenter radiotherapy of multiple targets where conformal multi-leaf collimator (MLC) trajectories may be used as the starting point for limited inverse optimization. Single isocenter radiotherapy of multiple targets may provide flexibility with less complex MLC trajectories, and fully block between targets with the MLC.

A computer-implemented method of performing a treatment fraction of radiation therapy comprises: determining a current position of a target volume of patient anatomy; based on the current position of the target volume, computing an accumulated dose for non-target tissue proximate the target volume; determining that the accumulated dose is less than a current value for a dose budget of the non-target tissue; and in response to the accumulated dose being less than the current value for the dose budget, applying a treatment beam to the target volume while the target volume is in the current position.

Systems, devices, and methods for quality assurance for verification of radiation dose delivery in arc-based radiation therapy devices using a 3D gamma evaluation method.

Devices, systems, and methods for planning radiosurgical treatments for neuromodulating a portion of the renovascular system may be used to plan radiosurgical neuromodulation treatments for conditions or disease associated with elevated central sympathetic drive. The renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as preganglionic positions. Target regions include the renal plexus, celiac ganglion, the superior mesenteric ganglion, the aorticorenal ganglion and the aortic plexus. Planning of radiosurgical treatments will optionally employ a graphical representation of a blood/tissue interface adjacent these targets.

Provided are a method for tracking tumor location and a radiotherapy apparatus, relating to the field of medical equipment technology. The method is applied to a radiotherapy apparatus comprising a first detector and at least one radiation source, and comprises emitting, from the radiation source, ray beams having a predetermined intensity, the ray beams being partially scattered after passing through a body lesion; receiving, by the first detector, a portion of scattered ray beams to acquire scattering data of the lesion; determining a relative location relationship between the lesion and a target region according to the acquired scattering data; and adjusting at least one of the ray beam intensity, lesion location and target region location according to the determined relative location relationship, such that the lesion receives irradiation of the ray beams having an adjusted predetermined intensity at the target region location.