A device for obtaining physiological information including plethysmographs of a medical patient and detecting a condition of pneumonia. The portable pneumonia screening device may include one or more sensors configured to obtain physiological information. The pneumonia screener may provide for methods of selecting and interfaces to assist selecting a patient's age group. The screener may match a selected age group from a set of programmed threshold level of oxygen saturation, respiratory, pulse rate, or other physiological parameters to assist pneumonia diagnosis. The pneumonia screener may provide one or more visual and/or audio stimuli, such as an animation, sound or music. The visual and/or audio stimuli may indicate initialization, diagnostic in progress, completion, or other events or progress of events. In some embodiments, the visual and/or auditory stimuli may be used to soothe or intrigue the patient such that patient agitation is reduced during the screening process.

The present disclosure relates to a device, method and system for calculating, estimating, or monitoring the blood pressure of a subject. At least one processor, when executing instructions, may perform one or more of the following operations. A first signal representing heart activity of the subject may be received. A second signal representing time-varying information on at least one pulse wave of the subject may be received. A first feature in the first signal may be identified. A second feature in the second signal may be identified. A pulse transit time based on a difference between the first feature and the second feature may be computed. The blood pressure of the subject may be calculated according to a first model based on the computed pulse transit time and a first set of calibration values, the first set of calibration values relating to the subject.

Embodiments herein relate to systems and methods for rapidly calibrating optical medical sensors. In an embodiment, a method can include placing a reflective optical medical sensor device on or in a patient. The reflective optical medical sensor device can include one or more optical emitters; one or more optical detectors; and a measurement circuit having one or more transimpedance amplifiers (TIA). The method can include setting the TIA to a fixed gain value and then turning on the optical emitter associated with each spatially unique measurement vector and receiving reflected light with the associated optical detector for each spatially unique measurement vector at the same fixed gain value. The method can include assessing the signal-to-noise (SNR) for each spatially unique measurement vector and selecting the spatially unique measurement vector having the highest SNR. Other embodiments are also included herein.

A wearable assembly has a pulse plethysmography (PPG) sensor and a piezoelectric pressure sensor and is attachable to a patient's finger or other area corresponding to a peripheral vascular region, and further includes a signal processor configured to monitor blood flow dependent measurements and pressure measurements over time, comparing these measurements to determine properties of the vascular region, such as vascular resistance of a blood vessel, vascular radius of the blood vessel, vascular stiffness of the vascular region, blood pressure, and/or cardiac vascular power. The signal processor may apply a hysteresis comparison of the sensor outputs, e.g., using an elliptical model, and in some examples may apply an extended Kalman filter for optimizing output of the vascular region properties.

The present invention provides a method (100) for determining at least one parameter related to the microcirculation function of a person, said method comprising the steps of a) determining (101) an arrival time (AT) of a pulse wave, wherein the AT is the time between the onset of an activity of the heart producing said pulse wave and the arrival of said pulse wave in a part of the body of said person; b) varying (102) an applied pressure (P) on said part of the body over time and determining said AT as a function of applied pressure and time; and c) assessing (103) said at least one parameter related to the microcirculation function based on said determination of AT and said AT as a function of applied pressure and time in steps a) and b). The present invention further provides a system (1) for determining at least one parameter.

The present disclosure relates to a device, method and system for calculating, estimating, or monitoring the blood pressure of a subject based on physiological features and personalized models. At least one processor, when executing instructions, may perform one or more of the following operations. A first signal representing a pulse wave relating to heart activity of a subject may be received. A plurality of second signals representing time-varying information on a pulse wave of the subject may be received. A personalized model for the subject may be designated. Effective physiological features of the subject based on the plurality of second signals may be determined. A blood pressure of the subject based on the effective physiological features and the designated model for the subject may be calculated.

Systems and methods for acquiring photoplethysmographic (PPG) signals for measuring blood pressure can include a computing device acquiring a sequence of images representing transdermal optical data of a subject, and generating a corresponding sequence of downsampled color frames. The computing device can identify, in each downsampled color frame, a respective central image block representing a central image region of the downsampled color frame and having a first size smaller than a second size of the downsampled color frame. The computing device can generate, for each downsampled color frame, a corresponding color intensity value based on the respective central image block. The computing device can generate, using color intensity values corresponding to the sequence of downsampled color frames, a PPG signal to determine a blood pressure value of the subject.

A measurement system and method of manufacture can include: a pressure resistant structure; a pressure inducer coupled to the pressure resistant structure, the pressure inducer having an engaged configuration, the engaged configuration of the pressure inducer increasing pressure exerted on a portion of a user in contact with the pressure resistant structure; a light source coupled to the pressure resistant structure; an optical sensor coupled to the pressure resistant structure and configured to detect a signal from the light source; a pressure sensor coupled to the pressure resistant structure, the pressure sensor configured to detect the pressure exerted on the portion of the user in contact with the pressure inducer; and a processor coupled to the optical sensor and the pressure sensor, the processor configured to correlate volumetric data from the optical sensor with pressure data from the pressure sensor and to provide a blood pressure measurement.

A wearable device for blood pressure monitoring, which includes an armband with an inner surface and an outer surface, an inflatable bladder within the armband, a pumping element for inflating and deflating the inflatable bladder, an optical sensor and a pressure sensor. The optical sensor is at least partially exposed at the inner surface of the armband.

Systems and methods for assessing PPG signals generated based on transdermal optical data can include a computing device generating a color intensity signal using an acquired sequence of transdermal images of a subject. The computing device can compute a signal quality metric of the color intensity signal. The computing device can provide an indication of a quality of the color intensity signal for display on a display device associated with the computing device. The indication of the quality of the color intensity signal can be determined based on the signal quality metric.